arXiv Computer Vision
MVC-Bench is a new benchmark designed to evaluate the calibration of vision‑language models (VLMs) and medical VLMs (Medical‑VLMs) for medical image classification. It tests calibration across robustness to modality, backbone, and domain shift; effectiveness of calibration strategies and prompt‑tuning methods; and stability under prompt‑template and random‑seed variations. The benchmark includes eight backbones, three medical modalities (fundus imaging, histopathology, chest X‑ray), and compares post‑hoc, train‑time, and zero‑shot calibration approaches, reporting accuracy, Expected Calibration Error (ECE), Maximum Calibration Error (MCE), and Adaptive Calibration Error (ACE) over 1,638 experiments, while also proposing a Multi‑Class Margin (MCM) regularization technique that improves ECE in most settings.
MVC-Bench is a calibration-focused benchmark for medical vision‑language models, evaluating how well these models express confidence across different modalities, backbones, and domain shifts. It tests robustness to modality, backbone, and domain changes, the effectiveness of calibration and prompt‑tuning strategies, and stability under prompt‑template and random‑seed variations. The benchmark includes 1638 experiments, reporting accuracy and Expected Calibration Error (ECE) along with other calibration metrics, and introduces a simple train‑time calibration method, Multi‑Class Margin (MCM) regularization, that achieves the lowest ECE in most settings.
arXiv:2606. 27023v1 Announce Type: new Abstract: Multimodal large language models (MLLMs) applied to Medical Visual Question Answering (VQA) tend to produce overconfident outputs regardless of actual correctness, and existing verbalized confidence calibration methods, developed primarily for text only LLMs, do not account for the multimodal nature of medical image understanding.
By Eren Senoglu, Federico Toschi, Nicolo Brunello, Andrea Sassella, Mark James Carman
arXiv:2607. 01902v1 Announce Type: cross Abstract: Reliable confidence estimates are essential in semantic segmentation, especially in safety-critical settings where overconfident errors can mislead downstream decisions.
By Tristan Kirscher (ICube), Kim-Celine Kahl (DKFZ), Balint Kovacs (DKFZ), Maximilian R. Rokuss (DKFZ), Klaus Maier-Hein (DKFZ), Xavier Coubez (ICube), Philippe Meyer (ICube), Sylvain Faisan (ICube)
Reliable confidence estimates are essential in semantic segmentation, especially in safety-critical settings where overconfident errors can mislead downstream decisions. Yet modern segmentation models often remain miscalibrated.
arXiv:2608.21300v1 Announce Type: new
Abstract: Foundation models for medical image segmentation, like prompt-based MedSAM, generalize well across domains and modalities, often in zero or few-shot se...
By Marko Haralovi\'c, Sounic Akkaraju, Carlo Baretta, Vasil Zapryanov, Alexia Briassouli
arXiv:2605. 18419v2 Announce Type: replace-cross Abstract: Vision-language models (VLMs) can couple visual perception with open-ended clinical reasoning, making them attractive for computational histopathology.
By Franciskus Xaverius Erick, Johanna Paula M\"uller, Bernhard Kainz
arXiv:2607. 05310v1 Announce Type: new Abstract: Model editing promises a fast, targeted way to correct post-deployment mistakes in medical vision-language models (VLMs) without costly retraining.
By Guli Zhu, Chenwei Wu, Liyue Shen
arXiv:2606. 23487v2 Announce Type: replace Abstract: Medical vision-language models (VLMs) such as BiomedCLIP generalize broadly, but adapting them to a clinical service is as much a safety problem as an accuracy one.
By Rishabh Jha, Amrita Singh, Prashanna Chudal
arXiv:2605. 30188v2 Announce Type: replace-cross Abstract: Reliable probability estimates are critical in many machine learning applications, yet modern classifiers are often poorly calibrated.
By Eug\`ene Berta, David Holzm\"uller, Francis Bach, Michael I. Jordan
arXiv:2606. 15910v2 Announce Type: replace Abstract: A vision-language model can answer a question about a chest radiograph or a pathology slide fluently and confidently while barely using the image, relying instead on language priors.
By Reza Khanmohammadi, Kundan Thind, Mohammad M. Ghassemi
arXiv:2608.22059v1 Announce Type: cross
Abstract: Pretrained image encoders are central to medical image classification, where expert annotation is costly and task-specific cohorts are often limited....
By Xingtao Lin, Hangqi Ren, Caiwan Sun, You Chen
arXiv:2511. 18676v2 Announce Type: replace-cross Abstract: Current vision-language models (VLMs) in medicine are primarily designed for categorical question answering (e.
By Yongcheng Yao, Yongshuo Zong, Raman Dutt, Yongxin Yang, Sotirios A Tsaftaris, Timothy Hospedales