arXiv AI

Reduced NEXI protocol for the quantification of human gray matter microstructure on the Connectome 2.0 scanner

arXiv:2509. 09513v3 Announce Type: replace-cross Abstract: Biophysical diffusion MRI models like Neurite Exchange Imaging (NEXI) are essential for probing gray matter microstructure, estimating compartment diffusivities, neurite fraction, and exchange time.

arXiv AI
Jun 2

A physics-informed foundation model for quantitative diffusion MRI

arXiv:2606. 00156v1 Announce Type: cross Abstract: Understanding the human brain requires access to its microscopic tissue architecture.

By Zihan Li, Jialan Zheng, Ziyu Li, Xun Yuan, Kasidit Anmahapong, Ziang Wang, Mingxuan Liu, Hongjia Yang, Yifei Chen, Zhuhao Wang, Yuhang He, Fang Chen, Rui Li, Huaiqiang Sun, Yi Liao, Congyu Liao, Yang Yang, Haibo Qu, Xue Zhang, Hongen Liao, Qiyuan Tian
arXiv Computer Vision
6d ago

Cross-Modality Structural Guidance in 3D Latent Diffusion for Robust FLAIR Super-Resolution

The paper introduces MR‑DiffuSR, a 3‑D latent diffusion framework that uses high‑resolution T1w structural priors to guide super‑resolution of thick‑slice FLAIR MRI scans. By applying cross‑modality structural swin attention and a mixed‑scale degradation strategy, the method avoids hallucinations and remains robust across varying slice thicknesses. On ADNI datasets, MR‑DiffuSR outperforms CNN and 2‑D diffusion baselines, achieving high PSNR, SSIM, and low LPIPS, and maintains strong white‑matter hyperintensity segmentation performance even at 7 mm equivalent slice thickness.

By Haoyu Lan, Jiazhen Zhang, John Onofrey, Bino Varghese, Nasim Sheikh-Bahaei, Arthur W. Toga, Jeiran Choupan
arXiv Statistics ML
6d ago

Bayesian Uncertainty Quantification for fMRI Functional Connectivity via Simulation-Based Inference

The paper introduces a Bayesian framework that models BOLD dynamics as coupled Ornstein‑Uhlenbeck processes and uses Sequential Neural Posterior Estimation to produce connectivity posteriors while accounting for measurement noise. Applied to 28 healthy controls scanned at 7T, the method quantifies uncertainty from scanner noise, subject variability, and scan length, revealing that about 46 voxels per ROI and 7 minutes of 7T data suffice for 90% of asymptotic precision. It also shows that 7T achieves within‑session precision 40% faster than 3T and requires roughly 37 times less per‑subject scan time to reach population‑level convergence, offering concrete, scanner‑specific guidance for protocol optimization.

By Simon Carter, Zeming Kuang, Lilianne R. Mujica-Parodi, Helmut H. Strey
arXiv AI
Aug 3

Dense Temporal Contrast Synthesis via Conditioned Latent Transport

arXiv:2607. 29394v1 Announce Type: cross Abstract: Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is essential for breast cancer management, but reliance on gadolinium-based contrast agents (GBCAs) restricts use in contraindicated populations, prolongs scan protocols, and presents environmental toxicity concerns.

By Smriti Joshi, Apostolia Tsirikoglou, Daniel M. Lang, Richard Osuala, Noah M\'arquez Varaa, Alejandro Guzman, Grzegorz Skorupko, Sebastian Ibarra Arregui, Lidia Garrucho, Akane Ohashi, Dimitra Ntoula, Eugen Divjak, O\u{g}uz Lafc{\i}, Jan C. Peeken, Julia A. Schnabel, Fredrik Strand, Oliver Diaz, Karim Lekadir
arXiv AI
Jul 9

Heterogeneity-Adaptive Diffusion Schrodinger Bridge for PET-Guided Whole-Body MRI Translation

arXiv:2607. 07401v1 Announce Type: cross Abstract: While whole-body multimodal medical imaging scanners have been increasingly recognized for more effective medical applications, the excessive long acquisition time in PET-MR scanning is a major obstacle in more efficient clinical practice.

By Chengbo Wang, Jiacheng Yu, Linjie Bian, Ming Qi, Xiaosheng Liu, Tongtong Che, Jichang Zhang, Shuyu Li, Shaoli Song, Xiuying Wang
arXiv Computer Vision
Sep 2

Prior-Guided Implicit Neural Representations for Single-Subject Diffusion MRI Super-Resolution

The paper introduces a transfer‑learning framework that pre‑trains an implicit neural representation (INR) on a high‑resolution diffusion MRI template and then adapts it to individual subjects through registration and fine‑tuning. This approach enables native single‑subject super‑resolution, achieving a 4× through‑plane up‑sampling from 5 mm to 1.25 mm on Human Connectome Project data. Compared to a recent baseline, the method reduces NRMSE by 36–49 % and increases FSIM by 24–43 %, while training 6× faster and outperforming other INR‑based techniques on both image quality and domain‑specific metrics.

By Abdulkader Ghandoura, Marsil Zakour, William Consagra, Yogesh Rathi
arXiv Machine Learning
Aug 28

Quantitative mapping from conventional MRI using self-supervised physics-guided deep learning: applications to a large-scale, clinically heterogeneous dataset

This study introduces a self‑supervised, physics‑guided deep‑learning framework that converts standard clinical T1‑, T2‑, and FLAIR MRIs into quantitative T1, T2, and proton‑density maps. Trained on 4,121 scan sessions from four different 3 T scanners over six years, the method produces maps whose white‑ and gray‑matter values fall within literature ranges and shows minimal variation across scanner hardware and acquisition protocols (coefficients of variation ≤ 1.1 %). Voxel‑wise reproducibility is high, with Pearson and concordance correlation coefficients above 0.82 for T1 and T2 and mean relative differences below 6 % for T2.

By Jelmer van Lune, Stefano Mandija, Oscar van der Heide, Matteo Maspero, Martin B. Schilder, Jan Willem Dankbaar, Cornelis A. T. van den Berg, Alessandro Sbrizzi
Hugging Face Trending Papers
Jul 8

Heterogeneity-Adaptive Diffusion Schrodinger Bridge for PET-Guided Whole-Body MRI Translation

While whole-body multimodal medical imaging scanners have been increasingly recognized for more effective medical applications, the excessive long acquisition time in PET-MR scanning is a major obstacle in more efficient clinical practice. Deep learning-based MRI translation provides a potential solution to reduce scan duration.

arXiv Machine Learning
Aug 11

A continually expandable foundation model for brain MRI

arXiv:2608. 08319v1 Announce Type: cross Abstract: Brain magnetic resonance imaging (MRI) is central to neuroscience and clinical assessment, but models are commonly developed for individual diseases, populations or imaging protocols.

By Michail Mamalakis, Carmen Jimenez-Mesa, Yonghao Li, Hao Chen, Chao Li, Antonios Mamalakis, John Suckling, Richard Bethlehem, Stephen J. Price, Richard J. Gilbertson, Pietro Lio