arXiv AI

Longitudinal Lesion Inpainting in Brain MRI via 3D Region Aware Diffusion

arXiv:2603. 05693v2 Announce Type: replace-cross Abstract: Accurate longitudinal analysis of brain MRI is often hindered by evolving lesions, which bias automated neuroimaging pipelines.

arXiv Computer Vision
Aug 21

4DLoG: Generative Modeling of Neurodegenerative Brain Anatomy with 4D Longitudinal Diffusion Model

arXiv:2604. 22700v2 Announce Type: replace Abstract: Modeling and predicting neurodegenerative disease progression from medical images remains a major challenge in medical AI, with significant implications for early diagnosis, disease monitoring, and treatment planning.

By Nivetha Jayakumar, Swakshar Deb, Bahram Jafrasteh, Qingyu Zhao, Miaomiao Zhang
arXiv AI
Aug 24

Consistency Models for Fast MRI Reconstruction Using Regularization by Denoising

The paper introduces CM-RED, a fast MRI reconstruction method that combines a pretrained consistency model with the regularization by denoising framework. By integrating controlled noise injection into accelerated proximal gradient updates, CM-RED achieves high‑quality reconstructions on fastMRI knee and brain datasets with only four network function evaluations. It consistently outperforms existing diffusion‑ and consistency‑based approaches in quantitative metrics, visual fidelity, and robustness to hyperparameter changes.

By Merve G\"ulle, Junno Yun, Ya\c{s}ar Utku Al\c{c}alar, Mehmet Ak\c{c}akaya
arXiv Machine Learning
Jun 18

Structural MRI Synthesis for Alzheimer's Disease via Conditional Diffusion on Anatomical Masks

arXiv:2606. 18354v1 Announce Type: cross Abstract: Recent advances in generative machine learning models have significantly improved medical imaging, offering promising solutions for data augmentation, privacy preservation, and improved model generalization.

By Muge Zhang, Muhammad Ali Khaliq, Jamal Alsakran, Byeong Kil Lee, Jeeho Ryoo
arXiv Computer Vision
Sep 23

Uncertainty-Aware 3D Residual Wavelet Diffusion for Ultra Low-Field MRI Super-Resolution

The paper introduces a 3D residual wavelet diffusion model for super‑resolving ultra low‑field MRI scans. By using a lossless wavelet reparameterisation, residual shifting, and domain randomisation, the method fits whole‑brain data on a single GPU, speeds up sampling, and generalises across scanners. It achieves volumetric accuracy comparable to leading regression approaches while producing per‑voxel uncertainty maps that reveal under‑determined regions and preserves disease‑relevant atrophy in cognitively impaired subjects.

By Rui W. Yeow, Millie Beament, Fred Dick, Raha Razin, Martina Bocchetta, David L. Thomas, Henry F. J. Tregidgo, Daniel C. Alexander, James H. Cole
arXiv Machine Learning
Jun 16

Lesion-DDPM: Lesion-Enhanced 3D Diffusion for MS MRI Synthesis

arXiv:2606. 15457v1 Announce Type: cross Abstract: 3D FLAIR MRI is widely recommended as one of the standard MRI sequences for brain imaging in multiple sclerosis (MS), but publicly available MS datasets remain relatively small and vary across scanners, acquisition protocols, and lesion patterns.

By Weidong Zhang, Yongchan Jung, Shafayat Mowla Anik, Furen Xiao, Vasudevan Janarthanan, Enkhzaya Chuluunbaatar, Byeong Kil Lee, Jeeho Ryoo
arXiv Computer Vision
6d ago

Cross-Modality Structural Guidance in 3D Latent Diffusion for Robust FLAIR Super-Resolution

The paper introduces MR‑DiffuSR, a 3‑D latent diffusion framework that uses high‑resolution T1w structural priors to guide super‑resolution of thick‑slice FLAIR MRI scans. By applying cross‑modality structural swin attention and a mixed‑scale degradation strategy, the method avoids hallucinations and remains robust across varying slice thicknesses. On ADNI datasets, MR‑DiffuSR outperforms CNN and 2‑D diffusion baselines, achieving high PSNR, SSIM, and low LPIPS, and maintains strong white‑matter hyperintensity segmentation performance even at 7 mm equivalent slice thickness.

By Haoyu Lan, Jiazhen Zhang, John Onofrey, Bino Varghese, Nasim Sheikh-Bahaei, Arthur W. Toga, Jeiran Choupan
arXiv AI
Sep 4

RARF: Region-Aware Rectified Flows for 3D Brain MRI Inpainting

RARF is a task‑agnostic, region‑aware rectified flow framework designed for 3D brain MRI inpainting. It limits stochastic interpolation to the inpainting region while keeping observed voxels fixed, using a 3D neural network that processes a partially voided image, Gaussian noise, a mask, and a timestep. The model is trained with masked flow‑matching and reconstruction‑consistency objectives, and during inference it transports noise toward a plausible reconstruction that preserves anatomical consistency, achieving competitive results on the BraTS Inpainting Challenge 2026.

By Tomas Guija-Valiente, Blanca Rodriguez-Gonzalez, Norberto Malpica, Angel Torrado-Carvajal
Hugging Face Trending Papers
Jun 23

Prob-BBDM: a Probabilistic Brownian Bridge Diffusion Model for MRI sequence image-to-image translation

AI-driven image-to-image synthesis is rapidly advancing, with growing applications in medical imaging. Multi-modal image analysis plays a crucial role in optimizing examination quality, yet acquiring multiple imaging modalities in clinical settings remains resource-intensive and time-consuming, especially for 3D imaging.

arXiv AI
Sep 16

MUMINS: Metadata-conditioned Uncertainty-aware Medical Image Next-state Synthesis

arXiv:2609.17169v1 Announce Type: cross Abstract: Forecasting anatomical changes such as tumor growth and neurodegeneration is a challenging generative vision task. Morphological evolution is subtle...

By Anna Oliveras, Roger Mar\'i, Rafael Redondo, Oriol Guardi\`a, Cynthia Ifeyinwa Ugwu, Ana Tost, Bhalaji Nagarajan, Carolina Migliorelli, Vicent Ribas, Petia Radeva
arXiv AI
Jul 9

Heterogeneity-Adaptive Diffusion Schrodinger Bridge for PET-Guided Whole-Body MRI Translation

arXiv:2607. 07401v1 Announce Type: cross Abstract: While whole-body multimodal medical imaging scanners have been increasingly recognized for more effective medical applications, the excessive long acquisition time in PET-MR scanning is a major obstacle in more efficient clinical practice.

By Chengbo Wang, Jiacheng Yu, Linjie Bian, Ming Qi, Xiaosheng Liu, Tongtong Che, Jichang Zhang, Shuyu Li, Shaoli Song, Xiuying Wang