This study introduces a self‑supervised, physics‑guided deep‑learning framework that converts standard clinical T1‑, T2‑, and FLAIR MRIs into quantitative T1, T2, and proton‑density maps. Trained on 4,121 scan sessions from four different 3 T scanners over six years, the method produces maps whose white‑ and gray‑matter values fall within literature ranges and shows minimal variation across scanner hardware and acquisition protocols (coefficients of variation ≤ 1.1 %). Voxel‑wise reproducibility is high, with Pearson and concordance correlation coefficients above 0.82 for T1 and T2 and mean relative differences below 6 % for T2.
arXiv:2604. 27277v3 Announce Type: replace-cross Abstract: Brain MRI underpins a wide range of neuroscientific and clinical applications, yet most learning-based methods remain task-specific and require substantial labeled data.
arXiv:2606. 00100v1 Announce Type: cross Abstract: Self-supervised deep learning-based methods have shown great promise for accelerated magnetic resonance imaging (MRI) reconstruction, achieving high image quality without requiring fully sampled data for training.
arXiv:2607. 17782v1 Announce Type: cross Abstract: Foundation models pretrained using self-supervised learning have transformed computer vision by learning transferable representations from large-scale unlabeled data.
The paper introduces SIMS-MRI, a self‑supervised framework that performs single‑subject multi‑view MRI super‑resolution using implicit neural representations. It processes anisotropic multi‑view scans without pre‑ or post‑processing, employing a multi‑resolution hash‑encoded representation and learned inter‑view alignment to produce isotropic reconstructions. The method is validated on simulated brain and clinical prostate MRI datasets, and the code will be publicly released.
arXiv:2607. 20136v1 Announce Type: cross Abstract: Slice-to-volume reconstruction (SVR) is the standard method for obtaining high-resolution (HR) 3D fetal brain volumes from motion-corrupted 2D MRI slice stacks acquired in multiple orientations.
arXiv:2608.28787v1 Announce Type: new Abstract: Joint-embedding predictive architectures (JEPAs) have primarily been developed for self-supervised representation learning. Denoising JEPA (D-JEPA) rec...
Brain tissue microstructure estimation with machine learning provides higher computational efficiency than conventional fitting. However, machine learning still presents important limitations that hamper its clinical utility.
arXiv:2608.29246v1 Announce Type: cross Abstract: Late gadolinium enhancement (LGE) cardiac magnetic resonance (MR) imaging is the modality of choice to assess myocardial infarction (MI) lesions. Now...
The study presents a multimodal BrainAGE framework that fuses structural T1-weighted MRI with DeepCBV maps—vascular information synthesized from non‑contrast MRI—to estimate brain age more accurately. Using two separate 3D convolutional neural networks, the combined model achieved a mean absolute error of 3.95 years on cognitively normal controls, outperforming single‑modality models. Saliency analyses showed MRI highlighted white matter and cortical atrophy, while DeepCBV emphasized vascular‑rich regions, and the integrated approach revealed stronger differentiation between stable and progressive MCI, indicating sensitivity to early vascular changes.
Magnetic resonance imaging (MRI) super-resolution is vital for improving diagnostic accessibility, yet most methods treat it as a deterministic mapping from a fixed low-resolution input to a high-resolution target. This overlooks a key property of MRI acquisition physics: spatial resolution and signal-to-noise ratio (SNR) are inherently coupled, making any given low-resolution scan merely one of many possible realizations under varying acquisition trade-offs.
arXiv:2605. 24609v2 Announce Type: replace-cross Abstract: Artificial intelligence is increasingly integrated into radiotherapy workflows, yet such pipelines remain vulnerable to out-of-distribution image data that may introduce unexpected behavior in clinical tasks.
arXiv:2601. 20503v2 Announce Type: replace-cross Abstract: White matter hyperintensities (WMH) and ischaemic stroke lesions (ISL) are key imaging biomarkers of cerebral small vessel disease (SVD) detectable on magnetic resonance imaging (MRI).