arXiv Machine Learning

LTR-ICD: A Ranking-Aware Framework for Automatic ICD Coding

The paper introduces LTR-ICD, a ranking‑aware framework that treats automatic ICD coding as a combined classification and ranking problem rather than a pure classification task. By incorporating the order of diagnostic codes, the method improves the identification of high‑priority codes, achieving a 47% accuracy in correctly ranking primary diagnoses versus 20% for existing classifiers. The model also outperforms prior work on micro‑ and macro‑F1 scores, reaching 0.6065 and 0.2904 respectively.

arXiv AI
Sep 1

CoLa-ICD: A Knowledge-Enhanced Framework for Long-Tail Automated Medical Coding

CoLa-ICD is a knowledge‑enhanced framework designed to improve automatic medical coding of ICD codes in long, imbalanced clinical documents. It enriches ICD labels with external terms, models dependencies among related codes, and strengthens the alignment between label semantics and clinical evidence, particularly for rare codes. Experiments demonstrate that CoLa-ICD achieves state‑of‑the‑art performance in AUC, F1, and P@k, with larger gains in larger and sparser label spaces.

By Yihang Cheng, Veronica Liesaputra, Andrew Trotman
arXiv Machine Learning
Aug 4

xMICD: Explainable Representation of Multiple ICD Codes

arXiv:2608. 00935v1 Announce Type: new Abstract: Electronic Health Records (EHRs) are widely used for clinical risk prediction using machine learning.

By Pat Vatiwutipong, Kumkup Keeratisiwakul, Albert Phuoc Kien Van Truong, Nutcha Yodrabum, Wasin Pansiritanachot, Marvin N. Wright, Thanapon Noraset
arXiv Machine Learning
Jun 15

Automatic identification of diagnosis from hospital discharge letters via weakly supervised Natural Language Processing

arXiv:2410. 15051v3 Announce Type: replace-cross Abstract: Identifying patient diagnoses from hospital discharge letters is essential for large-scale cohort selection and epidemiological research, but traditional supervised approaches require extensive manual annotation, which is often impractical for large textual datasets.

By Vittorio Torri, Elisa Barbieri, Anna Cantarutti, Carlo Giaquinto, Francesca Ieva
arXiv AI
Aug 20

Key Coverage Matters: Semi-Structured Extraction of OCR Clinical Reports

The paper presents a method for extracting key information from OCR‑digitized clinical reports, addressing challenges posed by heterogeneous documents and noisy OCR output. It introduces an open key space that is iteratively mined, normalized, clustered, and verified to build a canonical key inventory, and defines key coverage as a metric for inventory completeness. Experiments on reports from over 20 hospitals using a 0.2B BERT model show that performance improves steadily with key coverage, achieving high F1 scores when the top 90 keys are covered and outperforming a fine‑tuned Qwen3‑0.6B baseline.

By Yu Wang, Yingyun Li, Ying Qin, Haiyang Qian
arXiv AI
Aug 19

Foundation Agents Meet Agentic Deep Research: Evidence-Grounded Clinical Code Forecasting

The paper introduces ICD-Deepresearch, a workflow that combines foundation models for electronic health records (EHR) and language models with medical search and ICD dictionaries to forecast future ICD codes for upcoming clinical encounters. It evaluates candidate code transitions by linking patient evidence, external clinical relations, and exact code semantics within a fixed top‑K budget, using SparseEHR for initial priors, GPT‑5 for complementary forecasts, and a final selection step that validates, deduplicates, and ranks candidates. The method achieves patient‑averaged precision/recall of 24.60/35.09% on MIMIC‑III and 25.14/48.32% on MIMIC‑IV, with physicians rating 51–68% of its retrieved documents as useful, outperforming standalone GPT‑5 web search and Medical Deep Research.

By Junda Wang, Meysam Ghaffari, Akshat Choube, Mohsen Sharifi Renani, Hong Yu, Carlos Morato
arXiv AI
Jul 13

Evaluating Retrieval-Augmented Generation vs. Long-Context Input for Clinical Reasoning over EHRs

arXiv:2508. 14817v2 Announce Type: replace-cross Abstract: Objective: To evaluate whether retrieval-augmented generation (RAG) can serve as an efficient alternative to long-context prompting for clinical reasoning over electronic health records (EHRs).

By Skatje Myers, Dmitriy Dligach, Timothy A. Miller, Samantha Barr, James Landefeld, Yanjun Gao, Matthew Churpek, Anoop Mayampurath, Majid Afshar