arXiv Machine Learning

LTR-ICD: A Ranking-Aware Framework for Automatic ICD Coding

The paper introduces LTR-ICD, a ranking‑aware framework that treats automatic ICD coding as a combined classification and ranking problem rather than a pure classification task. By incorporating the order of diagnostic codes, the method improves the identification of high‑priority codes, achieving a 47% accuracy in correctly ranking primary diagnoses versus 20% for existing classifiers. The model also outperforms prior work on micro‑ and macro‑F1 scores, reaching 0.6065 and 0.2904 respectively.

arXiv AI
Sep 1

CoLa-ICD: A Knowledge-Enhanced Framework for Long-Tail Automated Medical Coding

CoLa-ICD is a knowledge‑enhanced framework designed to improve automatic medical coding of ICD codes in long, imbalanced clinical documents. It enriches ICD labels with external terms, models dependencies among related codes, and strengthens the alignment between label semantics and clinical evidence, particularly for rare codes. Experiments demonstrate that CoLa-ICD achieves state‑of‑the‑art performance in AUC, F1, and P@k, with larger gains in larger and sparser label spaces.

By Yihang Cheng, Veronica Liesaputra, Andrew Trotman
arXiv Machine Learning
Aug 4

xMICD: Explainable Representation of Multiple ICD Codes

arXiv:2608. 00935v1 Announce Type: new Abstract: Electronic Health Records (EHRs) are widely used for clinical risk prediction using machine learning.

By Pat Vatiwutipong, Kumkup Keeratisiwakul, Albert Phuoc Kien Van Truong, Nutcha Yodrabum, Wasin Pansiritanachot, Marvin N. Wright, Thanapon Noraset
arXiv Machine Learning
Jun 15

Automatic identification of diagnosis from hospital discharge letters via weakly supervised Natural Language Processing

arXiv:2410. 15051v3 Announce Type: replace-cross Abstract: Identifying patient diagnoses from hospital discharge letters is essential for large-scale cohort selection and epidemiological research, but traditional supervised approaches require extensive manual annotation, which is often impractical for large textual datasets.

By Vittorio Torri, Elisa Barbieri, Anna Cantarutti, Carlo Giaquinto, Francesca Ieva
arXiv AI
1d ago

Instruction-Tuning Large Language Models with Medical Classification Data Improves ICD Coding of German Tumor Diagnoses

The study demonstrates that instruction‑tuning open‑weight large language models (LLMs) with over 500,000 public question‑answer pairs derived from ICD‑10‑GM, ICD‑O‑3, and OPS catalogues markedly improves ICD coding accuracy for German tumor diagnoses. After fine‑tuning, ICD‑10‑GM exact accuracy rose from 1.4–24 % to 41–58 %, and partial accuracy from 31–74 % to 73–83 %. The approach also eliminated malformed code outputs and achieved 99 % tumor‑diagnosis recognition, with performance scaling positively with model size but narrowing the gap between small and large models.

By Stefan Lenz, Lakisha Ortiz Rosario, Georg Vollmar, Arsenij Ustjanzew, Fatma Alickovic, Thomas Kindler, Torsten Panholzer
arXiv AI
Aug 20

Key Coverage Matters: Semi-Structured Extraction of OCR Clinical Reports

The paper presents a method for extracting key information from OCR‑digitized clinical reports, addressing challenges posed by heterogeneous documents and noisy OCR output. It introduces an open key space that is iteratively mined, normalized, clustered, and verified to build a canonical key inventory, and defines key coverage as a metric for inventory completeness. Experiments on reports from over 20 hospitals using a 0.2B BERT model show that performance improves steadily with key coverage, achieving high F1 scores when the top 90 keys are covered and outperforming a fine‑tuned Qwen3‑0.6B baseline.

By Yu Wang, Yingyun Li, Ying Qin, Haiyang Qian
arXiv Machine Learning
Sep 25

Language Specificity vs. Domain Diversity: Benchmarking Transformers for Bangla Medical NER

This study benchmarks transformer models for Bangla medical named entity recognition (NER), comparing BanglaBERT, multilingual BERT (mBERT), XLM‑RoBERTa, and GPT‑4o mini under zero‑shot and few‑shot prompting. Across a full test set of 3,179 samples, fine‑tuned XLM‑RoBERTa achieves a new state‑of‑the‑art F1‑score of 0.5959, while BanglaBERT lags with 0.4937, suggesting that domain diversity outweighs language specificity. The analysis shows high performance on Medicine and Specialist entities (F1 > 0.83) but lower accuracy on Symptoms (F1 0.4367), and demonstrates that fine‑tuned transformers outperform prompt‑only approaches by a factor of 3.76.

By Rakib Abdullah, Md. Maruful Islam Maruf
arXiv AI
Aug 19

Foundation Agents Meet Agentic Deep Research: Evidence-Grounded Clinical Code Forecasting

The paper introduces ICD-Deepresearch, a workflow that combines foundation models for electronic health records (EHR) and language models with medical search and ICD dictionaries to forecast future ICD codes for upcoming clinical encounters. It evaluates candidate code transitions by linking patient evidence, external clinical relations, and exact code semantics within a fixed top‑K budget, using SparseEHR for initial priors, GPT‑5 for complementary forecasts, and a final selection step that validates, deduplicates, and ranks candidates. The method achieves patient‑averaged precision/recall of 24.60/35.09% on MIMIC‑III and 25.14/48.32% on MIMIC‑IV, with physicians rating 51–68% of its retrieved documents as useful, outperforming standalone GPT‑5 web search and Medical Deep Research.

By Junda Wang, Meysam Ghaffari, Akshat Choube, Mohsen Sharifi Renani, Hong Yu, Carlos Morato