MedStruct‑S is a benchmark for semi‑structured information extraction from OCR‑derived clinical reports, covering key discovery, key‑conditioned QA, and end‑to‑end key‑value extraction. It contains 3,582 annotated real‑world report pages and evaluates models under unknown keys and OCR noise. Experiments show encoder‑only models excel at non‑null key‑conditioned QA, while fine‑tuned decoder‑only models achieve the strongest overall performance across model sizes.
By Yingyun Li, Yu Wang, Haiyang Qian
arXiv:2508. 16674v2 Announce Type: replace-cross Abstract: Medical report understanding from real-world document images is essential for generating patient-facing explanations and enabling structured information exchange in clinical systems.
By Fangxin Shang, Yuan Xia, Dalu Yang, Yahui Wang, Binglin Yang
arXiv:2604. 25605v2 Announce Type: replace-cross Abstract: Introduction: Semantic search, which retrieves documents based on conceptual similarity rather than keywords, offers advantages for retrieval of clinical information.
By Faith Wavinya Mutinda, Spandana Makeneni, Anna Lin, Shivaji Dutta, Irit R. Rasooly, Patrick Dibussolo, Shivani Kamath Belman, Hessam Shahriari, Kevin Murphy, Alex B. Ruan, Barbara H. Chaiyachati, Sanjay Chainani, Robert W. Grundmeier, Scott M. Haag, Jeffrey M. Miller, Heather M. Griffis, Ian M. Campbell
The paper introduces BRIE, a continuously maintainable benchmark for evaluating large language models (LLMs) in electronic health record (EHR) information retrieval. It presents a scalable framework that automatically generates question–answer pairs from longitudinal EHR notes, validated by nineteen clinicians. The benchmark allows assessment of multiple inference strategies and highlights that state‑of‑the‑art LLMs often miss clinically important information, especially when synthesis across documents is required.
By Jordan L. Cahoon, Chloe O. Stanwyck, Sulaiman Somani, Philip Chung, Kevin R Keet, Kameron C. Black, Andrea T. Fisher, Sarita Khemani, Jerry Liu, Stephen Ma, Saloni K. Maharaj, Rita M. Pandya, Eduardo Perez-Guerrero, Priyanka Pillai, Lisa Shieh, David J. H. Wu, James Xie, James C. McAvoy, Teresa Nguyen, Jessica Tran, Lucy Yin, Bridget Lin, Alison Callahan, Jason A. Fries, Nigam H. Shah, Emily Alsentzer
arXiv:2606. 12569v1 Announce Type: cross Abstract: We present EDEN (Emergency Department Electronic Notes), a new and unique large-scale corpus of clinical notes produced in Emergency Departments of Italian hospitals.
By Tiziano Labruna, Guido Bertolini, Pietro Ferrazzi, Bernardo Magnini
arXiv:2508. 14817v2 Announce Type: replace-cross Abstract: Objective: To evaluate whether retrieval-augmented generation (RAG) can serve as an efficient alternative to long-context prompting for clinical reasoning over electronic health records (EHRs).
By Skatje Myers, Dmitriy Dligach, Timothy A. Miller, Samantha Barr, James Landefeld, Yanjun Gao, Matthew Churpek, Anoop Mayampurath, Majid Afshar
The paper introduces BRIE, a scalable framework that automatically creates question–answer pairs from longitudinal electronic health record notes, validated by nineteen clinicians. It offers a continuously maintainable benchmark for evaluating large language models in clinical settings, addressing limitations of manual, costly, and quickly outdated existing benchmarks. Experiments across nine LLMs and five inference strategies reveal that even state‑of‑the‑art systems often miss clinically important information, especially for synthesis‑heavy queries.
arXiv:2605. 03301v2 Announce Type: replace-cross Abstract: De-identification of clinical text is a prerequisite for the secondary use of electronic health records.
By Jose D. Posada, David Love, Somalee Datta, Priya Desai
arXiv:2606. 12569v2 Announce Type: replace-cross Abstract: We present eCream-MedCorpus, a new and unique large-scale dataset of clinical notes produced in Emergency Departments of Italian hospitals.
By Tiziano Labruna, Guido Bertolini, Pietro Ferrazzi, Bernardo Magnini
arXiv:2606. 12569v3 Announce Type: replace-cross Abstract: We present eCREAM-MedCorpus, a new and unique large-scale dataset of clinical notes produced in Emergency Departments of Italian hospitals.
By Tiziano Labruna, Guido Bertolini, Pietro Ferrazzi, Bernardo Magnini
Synthetic Hospital is an open, fully synthetic longitudinal electronic health record benchmark created from public medical education material. It contains 1,268 patients and 5,602 encounters, with every diagnosis, finding, and temporal relation grounded in standard ontologies and traceable back to its source. Physicians could not reliably distinguish its records from real charts, and current frontier AI models perform significantly below human experts on tasks such as reconstructing problem lists and summarizing charts.
By Christine Park, Valerie Chen, Tim Dettmers
The paper introduces Clinical System One (CS1), a 4‑billion‑parameter decision model that rapidly produces typed judgments from clinical records. Trained on 12.4 million Q&A pairs from 3.6 million patients, CS1 can answer multiple questions in a single forward pass, providing probability estimates for uncertain cases. In evaluations on 963,408 held‑out patients and 21 external datasets, CS1 outperformed larger open models and, when paired with a language‑model agent, efficiently identified trial‑eligible patients with far fewer tokens.
By Andrew Zhang, Trinh T. L. Vuong, Sophia J. Wagner, Dongmin Bang, Tong Ding, Yuchang Su, Mary Cipperman, Christina S. Chen, Judith Lefkes, Ramin Kahidi, Ming Y. Lu, Caiwei Tian, Tianhao Luo, Jingnan Ma, Rowland Pettit, Long Phi Le, Faisal Mahmood