CoLa-ICD is a knowledge‑enhanced framework designed to improve automatic medical coding of ICD codes in long, imbalanced clinical documents. It enriches ICD labels with external terms, models dependencies among related codes, and strengthens the alignment between label semantics and clinical evidence, particularly for rare codes. Experiments demonstrate that CoLa-ICD achieves state‑of‑the‑art performance in AUC, F1, and P@k, with larger gains in larger and sparser label spaces.
By Yihang Cheng, Veronica Liesaputra, Andrew Trotman
The paper introduces Span-Centric Learning (SCL), a method that decouples coding knowledge acquisition from its application in full clinical documents. SCL first trains on short text spans to learn coding knowledge, then fine‑tunes on a small set of annotated documents, enabling an 8B LLM to outperform state‑of‑the‑art methods with only 248 full documents. The approach also yields explicit, human‑aligned supporting evidence for each predicted ICD code and can learn code knowledge from spans even when the codes are absent from the full documents.
By Xu Zhang, Wenxin Ma, Chenxu Wu, Rongsheng Wang, Zhiyang He, Xiaodong Tao, Kun Zhang, S. Kevin Zhou
arXiv:2607. 11954v1 Announce Type: cross Abstract: Clinical code prediction maps unstructured discharge summaries to ICD-10-CM leaf codes in a large, sparse, and deeply hierarchical label space.
By Amritpal Singh, Sebastian Torres, Khawar Shakeel, Syed Ahmad Chan Bukhari
arXiv:2608.20887v1 Announce Type: cross
Abstract: Automatic Medical Coding (AMC), which assigns standardized International Classification of Diseases (ICD) codes to clinical notes, is essential for m...
By Xubin Chen, Yipeng Zhou, Wen Sun, Chengkai Huang, Xiaoming Fu, Quan Z. Sheng
EHRAdapt is an adapter that maps electronic health record tuples directly into a frozen language model’s embedding space, using learned embeddings for modality, time gaps, and dedicated vectors for event codes. It represents each event vector as a sum of a frozen, ontology‑trained semantic prior and a low‑rank evidence residual, enabling robust learning even for rare clinical events. Experiments on four million patient records with three large language model backbones show that the full adapter outperforms all ablations in next‑event prediction and improves rare‑disease discrimination in classification tasks.
By Andre R Goncalves, Vincent Liu, Priyadip Ray
Generative approaches to automatic International Classification of Diseases (ICD) coding use large language models (LLMs) to predict ICD codes from clinical documents. However, original ICD code strin...
arXiv:2609.22734v1 Announce Type: cross
Abstract: Clinical domain classification plays an important role in organizing and analyzing large volumes of unstructured medical text. However, medical trans...
By Sravani Pottipati, Lakshmikar R. Polamreddy
The paper introduces LTR-ICD, a ranking‑aware framework that treats automatic ICD coding as a combined classification and ranking problem rather than a pure classification task. By incorporating the order of diagnostic codes, the method improves the identification of high‑priority codes, achieving a 47% accuracy in correctly ranking primary diagnoses versus 20% for existing classifiers. The model also outperforms prior work on micro‑ and macro‑F1 scores, reaching 0.6065 and 0.2904 respectively.
By Mohammad Mansoori, Amira Soliman, Farzaneh Etminani
arXiv:2609.15713v1 Announce Type: new
Abstract: Recent approaches to 30-day hospital readmission prediction rely on pre-trained language models applied to discharge summaries. Although these methods...
By Mohamad Najafi, Hongyun Fu, Mathias Brochhausen, Jian Wu, Yaohang Li
arXiv:2608. 00935v1 Announce Type: new Abstract: Electronic Health Records (EHRs) are widely used for clinical risk prediction using machine learning.
By Pat Vatiwutipong, Kumkup Keeratisiwakul, Albert Phuoc Kien Van Truong, Nutcha Yodrabum, Wasin Pansiritanachot, Marvin N. Wright, Thanapon Noraset
arXiv:2607. 15447v1 Announce Type: new Abstract: Recent research in clinical machine learning, focusing on outcome predictions in intensive care unit (ICU), has shifted from bespoke supervised models to foundation models, utilising modern representation learning methods.
By Jingteng Li, Alexander Capstick, Louise Rigny, Iona Biggart, Neil J Sebire, Payam Barnaghi
The paper introduces CAST, a concept-guided artifact suppression tuning framework that uses sparse autoencoders to identify and suppress note-specific artifacts in clinical language models. CAST labels latent features with an LLM-assisted pipeline and ICD‑10 constraints, then fine‑tunes the model while providing post‑hoc per‑concept attributions for auditability. In experiments on MIMIC‑IV discharge‑note mortality prediction, CAST outperforms standard fine‑tuned encoders and competes with strong LLM baselines while offering a feature‑level audit trail of clinical concepts and suppressed artifacts.
By Jin Mu, Guanhua Chen