arXiv AI

Instruction-Tuning Large Language Models with Medical Classification Data Improves ICD Coding of German Tumor Diagnoses

The study demonstrates that instruction‑tuning open‑weight large language models (LLMs) with over 500,000 public question‑answer pairs derived from ICD‑10‑GM, ICD‑O‑3, and OPS catalogues markedly improves ICD coding accuracy for German tumor diagnoses. After fine‑tuning, ICD‑10‑GM exact accuracy rose from 1.4–24 % to 41–58 %, and partial accuracy from 31–74 % to 73–83 %. The approach also eliminated malformed code outputs and achieved 99 % tumor‑diagnosis recognition, with performance scaling positively with model size but narrowing the gap between small and large models.

arXiv Computation and Language
Oct 22

Is a 9B Decision Foundation Model Needed for Symptom-to-Disease Classification? Fine-Tuning Clef-Flash Against TF-IDF Baselines

The paper evaluates whether a 9‑billion parameter decision foundation model, Clef‑Flash, is necessary for symptom‑to‑disease classification. Fine‑tuning the model on the 24‑class Symptom2Disease benchmark yields 95.42% accuracy, but simple TF‑IDF linear classifiers achieve higher accuracy (98.75%) with far faster inference. Ablation studies show that predictions can hinge on single descriptive clauses, indicating that the benchmark may not fully capture the model’s capabilities.

By S. M. Mahbub Uddin Ahmed
arXiv AI
Jul 10

Towards Precision Therapy in Hepatocellular Carcinoma: A Clinical-Reasoning LLM for Risk Stratification and Treatment Guidance

arXiv:2607. 08602v1 Announce Type: new Abstract: Hepatocellular carcinoma (HCC) is a common malignancy and a leading cause of cancer-related mortality.

By Peng Cui, Jitao Wang, Siyan Xue, Yao Huang, Haoming Xia, Dong Li, Dengxiang Liu, Weilin Wang, Liping Liu, Leida Zhang, Yunfu Cui, Tao Peng, Daolin Ji, Haitao Zhao, Wei Zhang, Xiaojuan Wang, Weijie Ma, Zongren Ding, Jinlong Li, Yuan Ding, Jiajing Zhao, Zhiyu Chen, Chengkun Yang, Ziyue Huang, Jiaqi Liu, Fusheng Liu, Yang Zhou, Xiaojuan Wang, Zhongquan Sun, Shiyun Bao, Xiaojun Wang, Ming Yang, Guangxin Li, Bin Shu, Yong Liao, Hongxuan Li, Yao Tang, Shizhong Yang, Yongyi Zeng, Yufeng Yuan, Yinpeng Dong, Jihui Hao, Jun Zhu, Jiahong Dong
arXiv AI
Jun 30

Primary ICD Category Prediction using LLM-based Probing

arXiv:2606. 28798v1 Announce Type: new Abstract: Objective: ICD codes are central to reimbursement, research, and population health surveillance, yet automated coding systems often struggle to integrate diagnostic signals from both clinical narratives and structured electronic health record (EHR) variables.

By Chengyuan Liu, Xinyue Zhang, Yao Li, Guanting Chen
arXiv Machine Learning
Sep 25

Language Specificity vs. Domain Diversity: Benchmarking Transformers for Bangla Medical NER

This study benchmarks transformer models for Bangla medical named entity recognition (NER), comparing BanglaBERT, multilingual BERT (mBERT), XLM‑RoBERTa, and GPT‑4o mini under zero‑shot and few‑shot prompting. Across a full test set of 3,179 samples, fine‑tuned XLM‑RoBERTa achieves a new state‑of‑the‑art F1‑score of 0.5959, while BanglaBERT lags with 0.4937, suggesting that domain diversity outweighs language specificity. The analysis shows high performance on Medicine and Specialist entities (F1 > 0.83) but lower accuracy on Symptoms (F1 0.4367), and demonstrates that fine‑tuned transformers outperform prompt‑only approaches by a factor of 3.76.

By Rakib Abdullah, Md. Maruful Islam Maruf
arXiv Computation and Language
3d ago

Labadain-MedQA: A Tetun Medical QA Dataset for Fine-Tuning and Evaluating Large Language Models

The paper introduces Labadain-MedQA, a Tetun medical question‑answering dataset created by translating MedAlpaca’s Medical Flashcards and WikiDoc Patient Information into Tetun with Gemini 2.5 Flash, yielding 39,077 QA pairs. Translation quality was evaluated on 50 random pairs, showing human translations scored higher than LLM‑generated ones for medical accuracy and fluency (4.43/5 vs. 4.02/5, p < 0.001). Fine‑tuning Gemma and Llama models with parameter‑efficient methods on this dataset improved performance on Tetun‑translated USMLE multiple‑choice questions by up to 10.79% relative accuracy.

By Gabriel de Jesus, S\'ergio Nunes