Automatic medical coding assigns ICD codes to clinical notes, but it remains challenging due to long documents, imbalanced label distributions, and diverse terms. These challenges are especially sever...
The paper introduces Span-Centric Learning (SCL), a method that decouples coding knowledge acquisition from its application in full clinical documents. SCL first trains on short text spans to learn coding knowledge, then fine‑tunes on a small set of annotated documents, enabling an 8B LLM to outperform state‑of‑the‑art methods with only 248 full documents. The approach also yields explicit, human‑aligned supporting evidence for each predicted ICD code and can learn code knowledge from spans even when the codes are absent from the full documents.
By Xu Zhang, Wenxin Ma, Chenxu Wu, Rongsheng Wang, Zhiyang He, Xiaodong Tao, Kun Zhang, S. Kevin Zhou
EHRAdapt is an adapter that maps electronic health record tuples directly into a frozen language model’s embedding space, using learned embeddings for modality, time gaps, and dedicated vectors for event codes. It represents each event vector as a sum of a frozen, ontology‑trained semantic prior and a low‑rank evidence residual, enabling robust learning even for rare clinical events. Experiments on four million patient records with three large language model backbones show that the full adapter outperforms all ablations in next‑event prediction and improves rare‑disease discrimination in classification tasks.
By Andre R Goncalves, Vincent Liu, Priyadip Ray
arXiv:2607. 11954v1 Announce Type: cross Abstract: Clinical code prediction maps unstructured discharge summaries to ICD-10-CM leaf codes in a large, sparse, and deeply hierarchical label space.
By Amritpal Singh, Sebastian Torres, Khawar Shakeel, Syed Ahmad Chan Bukhari
arXiv:2608.20887v1 Announce Type: cross
Abstract: Automatic Medical Coding (AMC), which assigns standardized International Classification of Diseases (ICD) codes to clinical notes, is essential for m...
By Xubin Chen, Yipeng Zhou, Wen Sun, Chengkai Huang, Xiaoming Fu, Quan Z. Sheng
arXiv:2609.22734v1 Announce Type: cross
Abstract: Clinical domain classification plays an important role in organizing and analyzing large volumes of unstructured medical text. However, medical trans...
By Sravani Pottipati, Lakshmikar R. Polamreddy
arXiv:2607. 15447v1 Announce Type: new Abstract: Recent research in clinical machine learning, focusing on outcome predictions in intensive care unit (ICU), has shifted from bespoke supervised models to foundation models, utilising modern representation learning methods.
By Jingteng Li, Alexander Capstick, Louise Rigny, Iona Biggart, Neil J Sebire, Payam Barnaghi
arXiv:2609.15713v1 Announce Type: new
Abstract: Recent approaches to 30-day hospital readmission prediction rely on pre-trained language models applied to discharge summaries. Although these methods...
By Mohamad Najafi, Hongyun Fu, Mathias Brochhausen, Jian Wu, Yaohang Li
arXiv:2608. 00935v1 Announce Type: new Abstract: Electronic Health Records (EHRs) are widely used for clinical risk prediction using machine learning.
By Pat Vatiwutipong, Kumkup Keeratisiwakul, Albert Phuoc Kien Van Truong, Nutcha Yodrabum, Wasin Pansiritanachot, Marvin N. Wright, Thanapon Noraset
Generative approaches to automatic International Classification of Diseases (ICD) coding use large language models (LLMs) to predict ICD codes from clinical documents. However, original ICD code strin...
The paper introduces ICD-Deepresearch, a workflow that combines foundation models for electronic health records (EHR) and language models with medical search and ICD dictionaries to forecast future ICD codes for upcoming clinical encounters. It evaluates candidate code transitions by linking patient evidence, external clinical relations, and exact code semantics within a fixed top‑K budget, using SparseEHR for initial priors, GPT‑5 for complementary forecasts, and a final selection step that validates, deduplicates, and ranks candidates. The method achieves patient‑averaged precision/recall of 24.60/35.09% on MIMIC‑III and 25.14/48.32% on MIMIC‑IV, with physicians rating 51–68% of its retrieved documents as useful, outperforming standalone GPT‑5 web search and Medical Deep Research.
By Junda Wang, Meysam Ghaffari, Akshat Choube, Mohsen Sharifi Renani, Hong Yu, Carlos Morato
arXiv:2606. 00031v1 Announce Type: cross Abstract: Coronary artery disease (CAD) remains one of the leading causes of death globally, highlighting the need for reliable predictive systems to support early diagnosis and risk assessment.
By Jeba Maliha, Md Rafiul Kabir