UniReg is a conditional unified model for medical image registration that adapts deformation field estimation based on anatomical priors, registration type constraints, and instance-specific features. It combines the precision of task‑specific learning with the generalization of traditional optimization, enabling effective alignment across diverse CT and MR scenarios within a single framework. Experiments show UniReg outperforms state‑of‑the‑art learning‑based methods in accuracy while providing strong cross‑scenario generalization and reducing training cost and model redundancy.
By Zi Li, Jianpeng Zhang, Tai Ma, Tony C. W. Mok, Yan-Jie Zhou, Zeli Chen, Xianghua Ye, Le Lu, Cheng Chen, Dakai Jin
The paper introduces Recursive Uncertainty-Gated Image Registration (RUGI), an iterative refinement method that updates deformation fields predicted by learning-based registration models using a gating map. Two gating strategies are explored: an uncertainty-based approach and an image residual error approach, both concentrating updates on difficult regions. Experiments on cardiac MRI and echocardiography datasets show that RUGI consistently improves registration accuracy, with the error-gated variant reducing MSE by 27‑37% on pretrained models and lowering ejection fraction estimation errors.
By Clara Rodrigo Gonz\'alez, Oscar Bates, Fu Siong Ng, Meng-Xing Tang
The paper examines how residual misalignments from registration procedures introduce structured label noise in supervised synthetic CT (sCT) generation. It shows that voxel‑wise metrics are heavily influenced by the consistency between training and evaluation registrations, and that training with anatomically consistent registrations reduces variability and improves robustness. Introducing a perceptual loss based on a pretrained Segment Anything encoder yields sharper, more anatomically coherent sCT and highlights the need for anatomy‑oriented evaluation.
By Valentin Boussot, Cedric Hemon, Caroline Lafond, Jean-Claude Nunes, Jean-Louis Dillenseger
The paper introduces M2CG, a one-pass deformable image registration network that replaces recursive refinement with multi-level, multi-space contextual guidance. M2CG performs progressive pyramid registration within a single iteration, leveraging cues from previous, current, and subsequent steps across image, image feature, segmentation, and segmentation feature spaces. It achieves state‑of‑the‑art results on eight public medical datasets in both unsupervised and semi‑supervised settings, challenging the prevailing reliance on recursive architectures.
By Yue Lin, Shenghai Wu, Mingyuan Meng
arXiv:2610.34600v1 Announce Type: new
Abstract: Objective. Deformable image registration remains challenging because corresponding anatomy may exhibit different intensity relationships. Hand-crafted...
By Mojtaba Safari, Mingzhe Hu, Shansong Wang, Suyang Xi, Joshua Lorenz, Sean Pitroda, Aytekin Oto, Ralph R. Weichselbaum, Xiaofeng Yang
Objective. Deformable image registration remains challenging because corresponding anatomy may exhibit different intensity relationships. Hand-crafted modality-robust descriptors such as Modality-Inde...
arXiv:2609.15669v1 Announce Type: cross
Abstract: Multimodal image registration is a key component of many clinical workflows, yet it remains challenging because corresponding anatomical structures o...
By Matteo Barbieri, Giammarco La Barbera, Juan Pablo De La Plata, Sabine Sarnacki, Isabelle Bloch, Pietro Gori
The paper introduces DPIF, a plug‑and‑play dual‑path interaction framework that can be integrated with any encoder‑decoder segmentation network. DPIF aligns cross‑view distributions using Sinkhorn optimal transport, decouples features via conditional mutual information to transfer knowledge within shared semantic spaces, and applies persistent homology‑based topological regularization to encode anatomical invariants. Experiments on a private echocardiography dataset and two public datasets show that DPIF‑enhanced models outperform single‑view baselines and achieve comparable performance to full‑data single‑view models while using only 40–60% of the data.
By Shuhuan Wang, Yuanyuan Cui, Pengju Wang, Huimin Guo, Ling Yue, Yin Gu, Yanchao Zhang, Wei Feng, Yunhe Liu, Wei Qian, Mingjun Xu, Shuang Liu, He Ma
arXiv:2607. 23343v1 Announce Type: cross Abstract: Intraoperative 2D/3D registration aligns preoperative CT volumes with intraoperative X-ray or fluoroscopic images and is essential for image-guided interventions.
By Minheng Chen, Youyong Kong
arXiv:2606. 16153v1 Announce Type: cross Abstract: Medical image segmentation plays a critical role in clinical diagnostics, treatment planning, disease monitoring, and neurological disorder identification.
By Pengyu Zhu, Xiaojing Zhang, Kunbo Zhang, Chunyan Zhang, Zhenyu Wang
arXiv:2606. 10713v1 Announce Type: cross Abstract: The nnU-Net has demonstrated continuous success in medical segmentation tasks, which heavily rely on the availability and diversity of annotated biomedical data.
By Ana Sofia Santos, Andr\'e Ferreira, Gijs Luijten, Naida Solak, Lisle Faray de Paiva, Behrus Hinrichs-Puladi, Jens Kleesiek, Jan Egger, Victor Alves
arXiv:2608.22532v1 Announce Type: new
Abstract: Domain shift across imaging modalities and acquisition sites remains a significant barrier to the clinical deployment of segmentation models. Source-fr...
By Tal Grossman, Noa Cahan, Hayit Greenspan