UniReg is a conditional unified model for medical image registration that adapts deformation field estimation based on anatomical priors, registration type constraints, and instance-specific features. It combines the precision of task‑specific learning with the generalization of traditional optimization, enabling effective alignment across diverse CT and MR scenarios within a single framework. Experiments show UniReg outperforms state‑of‑the‑art learning‑based methods in accuracy while providing strong cross‑scenario generalization and reducing training cost and model redundancy.
By Zi Li, Jianpeng Zhang, Tai Ma, Tony C. W. Mok, Yan-Jie Zhou, Zeli Chen, Xianghua Ye, Le Lu, Cheng Chen, Dakai Jin
Deformable image registration (DIR) is a core problem in medical image analysis; but, unlike labeling decision problems such as classification and segmentation, registration is a problem class that involves stringent physical constraints. Although deep learning methods have made faster registration possible, the resulting models are often difficult to interpret compared to hand-crafted methods with explicit objectives and interpretable physical meaning.
The paper introduces Recursive Uncertainty-Gated Image Registration (RUGI), an iterative refinement method that updates deformation fields predicted by learning-based registration models using a gating map. Two gating strategies are explored: an uncertainty-based approach and an image residual error approach, both concentrating updates on difficult regions. Experiments on cardiac MRI and echocardiography datasets show that RUGI consistently improves registration accuracy, with the error-gated variant reducing MSE by 27‑37% on pretrained models and lowering ejection fraction estimation errors.
By Clara Rodrigo Gonz\'alez, Oscar Bates, Fu Siong Ng, Meng-Xing Tang
arXiv:2607.12896v3 Announce Type: replace
Abstract: Medical image segmentation foundation models are expected to generalize across diverse clinical scenarios, yet existing universal methods remain fr...
By Yunzhou Li, Jiesi Hu, Yanwu Yang, Hanyang Peng, Chenfei Ye, Jianfeng Cao, Yixuan Yuan, Ting Ma
arXiv:2606. 10713v1 Announce Type: cross Abstract: The nnU-Net has demonstrated continuous success in medical segmentation tasks, which heavily rely on the availability and diversity of annotated biomedical data.
By Ana Sofia Santos, Andr\'e Ferreira, Gijs Luijten, Naida Solak, Lisle Faray de Paiva, Behrus Hinrichs-Puladi, Jens Kleesiek, Jan Egger, Victor Alves
arXiv:2607. 09481v1 Announce Type: cross Abstract: Text-guided medical image segmentation leverages clinical semantics to improve lesion delineation, yet many existing models bind cross-modal fusion, supervision, and decoder design into a task-specific architecture.
By Yungeng Liu, Xuanzi Fang, Haijin Zeng, Qi Dai, Yongyong Chen
arXiv:2410.14083v2 Announce Type: replace
Abstract: This paper describes a new spatial correspondence representation based on paired regions-of-interest (ROIs), for medical image registration. The di...
By Shiqi Huang, Tingfa Xu, Ziyi Shen, Shaheer Ullah Saeed, Wen Yan, Dean Barratt, Yipeng Hu
arXiv:2608. 07340v1 Announce Type: cross Abstract: Registration-based Few-shot medical image segmentation (RFMIS) aims to generate pseudo-labels for unlabeled images by warping a labeled image through registration.
By Jia Wang, Jiaming Cai, Zunying Hu, Zhanjie Wu, Jinyuan Liu, Hua Cheng, Yun Peng
arXiv:2512. 17605v2 Announce Type: replace-cross Abstract: Robust mammography registration is essential for clinically relevant applications like tracking disease progression in breast tissue.
By Svetlana Krasnova, Emiliya Starikova, Ilia Naletov, Andrey Krylov, Dmitry Sorokin
arXiv:2609.15669v1 Announce Type: cross
Abstract: Multimodal image registration is a key component of many clinical workflows, yet it remains challenging because corresponding anatomical structures o...
By Matteo Barbieri, Giammarco La Barbera, Juan Pablo De La Plata, Sabine Sarnacki, Isabelle Bloch, Pietro Gori
arXiv:2607. 22139v1 Announce Type: cross Abstract: Accurate pixel-level classification of coronary angiograms is critical for cardiovascular disease assessment, yet the field lacks standardized evaluation protocols.
By Dominik Bernard Lau, Hubert Malinowski, Jerzy Szyjut, Adam Brzeski, Tomasz Dziubich, Rados{\l}aw Targo\'nski, Tomasz Figatowski, Natalia Zieli\'nska
Multimodal image registration is a key component of many clinical workflows, yet it remains challenging because corresponding anatomical structures often exhibit substantially different image intensit...