The paper examines how residual misalignments from registration procedures introduce structured label noise in supervised synthetic CT (sCT) generation. It shows that voxel‑wise metrics are heavily influenced by the consistency between training and evaluation registrations, and that training with anatomically consistent registrations reduces variability and improves robustness. Introducing a perceptual loss based on a pretrained Segment Anything encoder yields sharper, more anatomically coherent sCT and highlights the need for anatomy‑oriented evaluation.
arXiv:2607. 23343v1 Announce Type: cross Abstract: Intraoperative 2D/3D registration aligns preoperative CT volumes with intraoperative X-ray or fluoroscopic images and is essential for image-guided interventions.
DALE-CT introduces depth‑aware 2D slice encoders that learn an anatomical world model of chest CT scans without 3D or positional supervision. By sampling self‑supervised views across a physical $z$‑axis slab, the encoder captures how anatomy changes between neighboring slices, enabling it to recover slice ordering and distinguish slices by anatomy alone. The model, trained on a large 287k‑scan corpus, achieves state‑of‑the‑art performance on CT‑RATE and is released with full code and evaluation tools.
arXiv:2410.14083v2 Announce Type: replace Abstract: This paper describes a new spatial correspondence representation based on paired regions-of-interest (ROIs), for medical image registration. The di...
arXiv:2608. 05960v1 Announce Type: cross Abstract: Routine CT interpretation is inherently comprehensive, capturing incidental findings across the entire scan volume.
arXiv:2608.28787v1 Announce Type: new Abstract: Joint-embedding predictive architectures (JEPAs) have primarily been developed for self-supervised representation learning. Denoising JEPA (D-JEPA) rec...
The paper presents the first systematic evaluation of out‑of‑distribution generalization for congenital heart disease (CHD) segmentation, using the ImageCHD cohort as a held‑out target. It compares several segmentation architectures under different training regimes, showing that in‑distribution performance is a poor predictor of cross‑cohort robustness: nnU‑Net drops from 0.77 to 0.51 Dice, while SwinUNETR maintains higher performance at 0.67 Dice. Limited target‑domain adaptation with only 11 labeled ImageCHD cases boosts all SwinUNETR variants above 0.76 Dice, highlighting the importance of explicit cross‑dataset testing.
The paper introduces Recursive Uncertainty-Gated Image Registration (RUGI), an iterative refinement method that updates deformation fields predicted by learning-based registration models using a gating map. Two gating strategies are explored: an uncertainty-based approach and an image residual error approach, both concentrating updates on difficult regions. Experiments on cardiac MRI and echocardiography datasets show that RUGI consistently improves registration accuracy, with the error-gated variant reducing MSE by 27‑37% on pretrained models and lowering ejection fraction estimation errors.
Congenital heart disease (CHD) diagnosis and surgical planning often require patient-specific 3D anatomical models, but manual segmentation is labor-intensive, particularly in complex anatomies. Altho...
The study explores how adding anatomical priors and active learning can improve the accuracy of deep learning models for segmenting the Clinical Target Volume (CTV) in gastric cancer radiotherapy. Using 100 retrospective CT scans, an nnU‑Net model trained on 10 expert‑contoured cases was enhanced with voxel‑wise anatomical prior maps and iterative active learning over four rounds. The combined approach raised the mean Dice Similarity Coefficient from 0.84 to 0.87, demonstrating that both techniques individually and together improve segmentation performance and generalizability.
Accurate segmentation of subcortical regions is critical for neurosurgical planning and functional research. Most automated methods rely on template space coregistration, which may compromise patient-specific accuracy, particularly in small structures.
UniReg is a conditional unified model for medical image registration that adapts deformation field estimation based on anatomical priors, registration type constraints, and instance-specific features. It combines the precision of task‑specific learning with the generalization of traditional optimization, enabling effective alignment across diverse CT and MR scenarios within a single framework. Experiments show UniReg outperforms state‑of‑the‑art learning‑based methods in accuracy while providing strong cross‑scenario generalization and reducing training cost and model redundancy.
arXiv:2606. 09953v1 Announce Type: cross Abstract: Head computed tomography (CT) typically uses sub-millimeter in-plane resolution but 2-5 mm through-plane spacing, creating substantial anisotropy that degrades multiplanar reconstructions, volumetric measurements such as hematoma volume estimation, and downstream algorithms that assume near-isotropic voxels.