arXiv:2601.17228v2 Announce Type: replace
Abstract: Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches e...
By Tengyue Zhang, Ruiwen Ding, Luoting Zhuang, Yuxiao Wu, Erika F. Rodriguez, William Hsu
arXiv:2602.14512v3 Announce Type: replace
Abstract: Autoregressive pretraining has been key to the scalability of large language models, yet medical generative foundation models remain predominantly...
By Zhicheng He, Yunpeng Zhao, Junde Wu, Ziwei Niu, Ziyue Wang, Bohan Li, Zijun Li, Lanfen Lin, Nan Liu, Yueming Jin
The paper introduces Dual Co-Train, a source‑free domain adaptation framework for ultrasound tongue segmentation that operates under extreme data scarcity. Starting from a lightweight UltraUNet pretrained on only five labeled images, the method iteratively refines pseudo‑labels, filters unreliable masks with a contour‑based quality‑control module, and generates target‑style synthetic image‑mask pairs via a segmentation‑guided conditional GAN. The student model is trained on a mix of clean pseudo‑labeled target images, noisy pseudo‑labels with consistency regularization, and synthetic samples, enabling closed‑loop adaptation without access to source data. Experiments on 12 source‑target transfer pairs across eight datasets show that this approach improves segmentation overlap and contour accuracy over both unsupervised baselines and supervised models.
By Alisher Myrgyyassov, Zhen Song, Bruce Xiao Wang, Yu Sun, Min Ney Wong, Yihao Zhou, Yongping Zheng
arXiv:2609.13043v1 Announce Type: new
Abstract: Robust medical image segmentation across imaging modalities is challenging because of large differences in appearance and intensity distributions. Mode...
By Ziliang Hong, Hongyi Pan, Halil Ertugrul Aktas, Andrea Bejar, Elif Keles, Frank H. Miller, Michael B. Wallace, Rajesh N. Keswani, Gorkem Durak, Ulas Bagci
arXiv:2608. 08135v1 Announce Type: cross Abstract: Cross-modality medical image translation can reduce the burden of multi-modal acquisitions, yet the field remains constrained by two coupled limitations: methods operate on 2D slices or 3D patches rather than whole volumes, and train a separate model for each translation task.
By Daniele Molino, Alessio Zoboli, Camillo Maria Caruso, Valerio Guarrasi, Paolo Soda
arXiv:2511.05782v3 Announce Type: replace
Abstract: Unsupervised domain adaptation (UDA) for medical image segmentation remains challenging due to substantial domain shifts across imaging modalities,...
By Lalit Maurya, Honghai Liu, Reyer Zwiggelaar
The paper introduces ANT, a test‑time adaptation framework that improves prostate cancer detection in micro‑ultrasound by performing a segmentation‑guided adaptation. ANT aligns a pretrained detection encoder to the target domain’s prostate anatomy using pseudo‑masks from a frozen segmentation network, thereby correcting domain‑specific feature drift while preserving cancer‑discriminative features. In a leave‑one‑center‑out evaluation, ANT raises mean AUC by 2.9% at the biopsy‑core level and 3.6% at the patient level compared to no adaptation, outperforming existing TTA baselines.
By Obed Korshie Dzikunu, Mohammad Mahdi Abootorabi, Mohamed Harmanani, Paul F. R. Wilson, Emma Willis, Ferdinand Luger, Adam Kinnaird, Brian Wodlinger, Parvin Mousavi, Purang Abolmaesumi
The paper proposes a two‑stage learning framework for multi‑organ segmentation that handles partially annotated datasets and domain shifts. First, the model learns accurate segmentations from available annotations to build robust feature representations. Second, it introduces learnable organ prototypes and a Sinkhorn‑triplet loss to enforce organ‑wise feature consistency across datasets, keeping embeddings of the same organ close while separating different organs, even when annotations are missing.
By Dakini Mallam Garba, Salim Abdou Daoura
arXiv:2605. 25402v2 Announce Type: replace-cross Abstract: Self-supervised pre-training paradigm has gained increasing prominence for learning transferable representations in medical imaging, yet existing methods for ultrasound (US) images operate at the image or frame level, overlooking the anatomical context for clinical-aligned representation learning.
By Chunzheng Zhu, Yijun Wang, Jianxin Lin, Feng Wang, Hongwei Wang, Lei Zhao, Shengli Li, Kenli Li
The paper introduces LowBridge, a method for cross‑modal medical image segmentation that leverages shared low‑level features such as edges between MRI and CT scans. It trains a generative model to reconstruct source‑modality images from edge maps and then trains a segmentation network on these generated images. At test time, edge features from target‑modality images are fed into the generative model to produce source‑style images, which are segmented by the pretrained network, achieving state‑of‑the‑art results on multiple public datasets.
By Pengfei Lyu, Pak-Hei Yeung, Jing Xia, De Hu, Xiaosheng Yu, Jianning Chi, Chengdong Wu, Jagath C. Rajapakse
The paper introduces an unsupervised domain adaptation framework that aligns redundancy-reducing features to enable accurate 3D segmentation of cone-beam CT (CBCT) without target-domain annotations or inference-time adaptation. The method is architecture-agnostic, working with both CNN-based and ViT-based foundation models, and is evaluated on two liver segmentation benchmarks for interventional vascular procedures and radiation therapy. Results show that even large pretrained segmentation networks need explicit feature-space bridging to generalize across diagnostic CT and CBCT, and the proposed approach consistently outperforms existing pretrained foundation models and UDA strategies.
By Gauthier Miralles, Loic Le Folgoc, Vincent Jugnon, Pietro Gori
arXiv:2608.31073v1 Announce Type: new
Abstract: Whole-heart segmentation (WHS) in computed tomography (CT) and magnetic resonance imaging (MRI) is affected by acquisition shifts and heterogeneous car...
By Jiacheng Wang, Ivana Isgum, Ipek Oguz