Magnetic resonance imaging (MRI) super-resolution is vital for improving diagnostic accessibility, yet most methods treat it as a deterministic mapping from a fixed low-resolution input to a high-resolution target. This overlooks a key property of MRI acquisition physics: spatial resolution and signal-to-noise ratio (SNR) are inherently coupled, making any given low-resolution scan merely one of many possible realizations under varying acquisition trade-offs.
The paper introduces a 3D residual wavelet diffusion model for super‑resolving ultra low‑field MRI scans. By using a lossless wavelet reparameterisation, residual shifting, and domain randomisation, the method fits whole‑brain data on a single GPU, speeds up sampling, and generalises across scanners. It achieves volumetric accuracy comparable to leading regression approaches while producing per‑voxel uncertainty maps that reveal under‑determined regions and preserves disease‑relevant atrophy in cognitively impaired subjects.
By Rui W. Yeow, Millie Beament, Fred Dick, Raha Razin, Martina Bocchetta, David L. Thomas, Henry F. J. Tregidgo, Daniel C. Alexander, James H. Cole
Foundation models such as Segment Anything Model 2 (SAM2) have transformed natural-image and video segmentation, and recent work has begun adapting them to medical imaging. These adaptations, however, are largely general-purpose models that treat MRI as one modality among many; large-scale, MRI-specific modelling and benchmarking remain limited, even though MRI's low soft-tissue contrast leaves many boundaries effectively invisible on individual slices.
Multi-parametric MRI is the gold standard for neuro-oncology, yet acquiring complete 4-modality protocols may be unfeasible in real-world clinical practice. When handling missing modalities, existing...
The paper introduces SIMS-MRI, a self‑supervised framework that performs single‑subject multi‑view MRI super‑resolution using implicit neural representations. It processes anisotropic multi‑view scans without pre‑ or post‑processing, employing a multi‑resolution hash‑encoded representation and learned inter‑view alignment to produce isotropic reconstructions. The method is validated on simulated brain and clinical prostate MRI datasets, and the code will be publicly released.
By Heejong Kim, Abhishek Thanki, Roel van Herten, Daniel Margolis, Mert R Sabuncu
CAPS is a Clinically‑Verifiable Anatomy‑Prioritized Synthesis framework designed to impute missing MRI modalities for brain tumor segmentation. It uses a hybrid loss (L₁ + L_AFP + L_DualDice) to preserve deep anatomical features and topological boundaries, achieving high synthesis fidelity and robust segmentation (82.38% mean Dice) on the BraTS Adult Glioma dataset. The method also generalizes well to unseen cohorts and has been validated by blinded radiologists, who report improved image quality and clinical utility.
By Cecilia Diana-Albelda, Arthur Longuefosse, Mario Rub\'en Paz Campos, \'Alvaro Garc\'ia-Mart\'in, Jesus Bescos
The paper introduces MR‑DiffuSR, a 3‑D latent diffusion framework that uses high‑resolution T1w structural priors to guide super‑resolution of thick‑slice FLAIR MRI scans. By applying cross‑modality structural swin attention and a mixed‑scale degradation strategy, the method avoids hallucinations and remains robust across varying slice thicknesses. On ADNI datasets, MR‑DiffuSR outperforms CNN and 2‑D diffusion baselines, achieving high PSNR, SSIM, and low LPIPS, and maintains strong white‑matter hyperintensity segmentation performance even at 7 mm equivalent slice thickness.
By Haoyu Lan, Jiazhen Zhang, John Onofrey, Bino Varghese, Nasim Sheikh-Bahaei, Arthur W. Toga, Jeiran Choupan
arXiv:2606. 19651v1 Announce Type: new Abstract: Three-dimensional (3D) brain MRI is central to clinical neurology and neuro-oncology, where generative models could augment under-represented cohorts, simulate disease trajectories, and support privacy-preserving data sharing.
By Max Van Puyvelde, Ibrahim Gulluk, Wim Van Criekinge, Olivier Gevaert
arXiv:2604. 06482v2 Announce Type: replace-cross Abstract: Time-resolved volumetric MR imaging that reconstructs a 3D MRI within sub-seconds to resolve deformable motion is essential for motion-adaptive radiotherapy.
By Jiacheng Xie, Hua-Chieh Shao, Can Wu, Ricardo Otazo, Jie Deng, Mu-Han Lin, Tsuicheng Chiu, Jacob Buatti, Viktor Iakovenko, You Zhang
arXiv:2606. 15457v1 Announce Type: cross Abstract: 3D FLAIR MRI is widely recommended as one of the standard MRI sequences for brain imaging in multiple sclerosis (MS), but publicly available MS datasets remain relatively small and vary across scanners, acquisition protocols, and lesion patterns.
By Weidong Zhang, Yongchan Jung, Shafayat Mowla Anik, Furen Xiao, Vasudevan Janarthanan, Enkhzaya Chuluunbaatar, Byeong Kil Lee, Jeeho Ryoo
arXiv:2610.08983v1 Announce Type: new
Abstract: Generative inpainting of brain MRI volumes is essential for synthesizing healthy tissue in pathological regions, improving the accuracy and reliability...
By Arnela Hadzic, Franz Thaler, Simon Johannes Joham, Martin Urschler
arXiv:2609.24468v2 Announce Type: replace
Abstract: Three-dimensional (3D) multi-contrast magnetic resonance imaging (MCMRI) provides rich anatomical and quantitative information but requires long ac...
By Jingran Xu, Dong Liang, Hairong Zheng, Yuanyuan Liu, Yanjie Zhu