Arbitrary-Scale Anisotropic 3D MRI Super-Resolution with Gaussian Prototypes
Read the original on arXiv Computer Vision →The Flow has not summarised this story yet — read it at arXiv Computer Vision.
The Flow has not summarised this story yet — read it at arXiv Computer Vision.
Magnetic resonance imaging (MRI) super-resolution is vital for improving diagnostic accessibility, yet most methods treat it as a deterministic mapping from a fixed low-resolution input to a high-resolution target. This overlooks a key property of MRI acquisition physics: spatial resolution and signal-to-noise ratio (SNR) are inherently coupled, making any given low-resolution scan merely one of many possible realizations under varying acquisition trade-offs.
The paper introduces a 3D residual wavelet diffusion model for super‑resolving ultra low‑field MRI scans. By using a lossless wavelet reparameterisation, residual shifting, and domain randomisation, the method fits whole‑brain data on a single GPU, speeds up sampling, and generalises across scanners. It achieves volumetric accuracy comparable to leading regression approaches while producing per‑voxel uncertainty maps that reveal under‑determined regions and preserves disease‑relevant atrophy in cognitively impaired subjects.
Foundation models such as Segment Anything Model 2 (SAM2) have transformed natural-image and video segmentation, and recent work has begun adapting them to medical imaging. These adaptations, however, are largely general-purpose models that treat MRI as one modality among many; large-scale, MRI-specific modelling and benchmarking remain limited, even though MRI's low soft-tissue contrast leaves many boundaries effectively invisible on individual slices.
Multi-parametric MRI is the gold standard for neuro-oncology, yet acquiring complete 4-modality protocols may be unfeasible in real-world clinical practice. When handling missing modalities, existing...
The paper introduces SIMS-MRI, a self‑supervised framework that performs single‑subject multi‑view MRI super‑resolution using implicit neural representations. It processes anisotropic multi‑view scans without pre‑ or post‑processing, employing a multi‑resolution hash‑encoded representation and learned inter‑view alignment to produce isotropic reconstructions. The method is validated on simulated brain and clinical prostate MRI datasets, and the code will be publicly released.
CAPS is a Clinically‑Verifiable Anatomy‑Prioritized Synthesis framework designed to impute missing MRI modalities for brain tumor segmentation. It uses a hybrid loss (L₁ + L_AFP + L_DualDice) to preserve deep anatomical features and topological boundaries, achieving high synthesis fidelity and robust segmentation (82.38% mean Dice) on the BraTS Adult Glioma dataset. The method also generalizes well to unseen cohorts and has been validated by blinded radiologists, who report improved image quality and clinical utility.