The paper presents a segmentation pipeline for brain metastases in both pre‑ and post‑treatment cases using a 5‑fold nnU‑Net ResEnc‑L ensemble trained on 1,296 four‑modality cases. A rule‑based post‑processing cascade improves the lesion‑wise Dice similarity coefficient (LW‑DSC) for enhancing tumour, tumour core, whole tumour, and resection cavity sub‑regions, achieving LW‑DSC scores of 0.733, 0.751, 0.713, and 0.549 respectively on the official validation leaderboard. The authors conduct a five‑fold out‑of‑fold analysis to validate the robustness of each post‑processing stage, provide a mechanistic explanation of LW‑DSC behaviour, and report thirteen negative results that challenge common intuitions, with all code released under Apache‑2.0.
By Haobin Liu, Xin Wang
The paper presents a pragmatic segmentation pipeline for brain metastases in the BraTS 2026 Task 1, using a 5‑fold nnU-Net ResEnc‑L ensemble trained for 1,000 epochs on 1,296 four‑modality cases. A rule‑based post‑processing cascade tuned for the lesion‑wise Dice similarity coefficient (LW‑DSC) improves performance, achieving LW‑DSC scores of 0.733, 0.751, 0.713, and 0.549 on enhancing tumour, tumour core, whole tumour, and resection cavity, respectively. The authors audit each post‑processing stage with a five‑fold out‑of‑fold analysis, confirm two stages as robust, and provide a mechanistic analysis of LW‑DSC, along with thirteen negative results that challenge common intuitions.
arXiv:2607. 22749v1 Announce Type: cross Abstract: Tracking residual tumor after surgery is essential for catching recurrence early, but automating post-operative glioma segmentation remains a difficult task.
By Alexandru Cri\c{s}an, Diana Borza
arXiv:2606. 19300v1 Announce Type: cross Abstract: Glioma segmentation in multiparametric MRI is a critical component of treatment planning.
By Xin Ci Wong, Duygu Sarikaya, Kieran Zucker, Marc De Kamps, Nishant Ravikumar
VGG16-MCA UNet is a hybrid neural network that combines an ImageNet‑pretrained VGG16 encoder with a decoder enhanced by a Multi‑Channel Attention module, trained using Focal Tversky loss to address class imbalance. The model was evaluated as a 2‑D, FLAIR‑only whole‑tumor segmenter on BraTS 2020 and LGG datasets, achieving a pixel‑level Dice of 95.10 % on BraTS and 88.32 % on LGG in a 5‑fold cross‑validation setting. Inference time is 66.32 ms per 256×256 slice on a single RTX 2060, only slightly slower than a VGG16‑UNet without attention.
whyItMatters":"The study provides a reproducible 2‑D FLAIR baseline for whole‑tumor segmentation, demonstrating high Dice scores and detailed reporting of training and evaluation protocols."
By Shubham Gajjar, Deep Joshi, Avi Poptani, Vishal Barot
arXiv:2609.15524v1 Announce Type: new
Abstract: BraTS-GoAT evaluates tumor segmentation across heterogeneous populations. We trained a conventional 3D nnU-Net on 1,351 labeled cases using five-fold c...
By Tristan Kirscher (ICube, Institut Strauss), Vivian Metzger (Institut Strauss), Philippe Meyer (Institut Strauss, ICube), Xavier Coubez (Institut Strauss, ICube)
The paper introduces a method for generalizable brain tumor segmentation in the BraTS 2026 Challenge. It builds on the nnU-Net framework with a large residual encoder, adding semi‑supervised learning via pseudo‑labels and a tumor‑aware deformable augmentation that locally deforms lesions while preserving surrounding anatomy. The approach improves Dice and NSD scores across all tumor regions compared to labeled‑only baselines, demonstrating the complementary benefits of self‑training and the proposed augmentation.
By Henrique Zan Grande, Jeovane Honorio Alves, Rayson Laroca, Andre Gustavo Hochuli
arXiv:2609.15888v1 Announce Type: cross
Abstract: Deep networks trained on structural MRI for Alzheimer's disease (AD) staging often reach reasonable accuracy while attending to anatomically irreleva...
By Paul-Gabriel Nicolae, Irina Georgiana Mocanu
arXiv:2512. 14937v2 Announce Type: replace-cross Abstract: Gliomas are the most common malignant brain tumors in adults and are among the most lethal.
By Abhijeet Parida, Daniel Capell\'an-Mart\'in, Zhifan Jiang, Nishad Kulkarni, Krithika Iyer, Austin Tapp, Syed Muhammad Anwar, Mar\'ia J. Ledesma-Carbayo, Marius George Linguraru
The paper introduces NeuroFusion, an assistive brain‑MRI report generator that surfaces latent tumor signals from a frozen Mistral‑7B backbone. By adding discriminative field‑classifier heads over per‑lesion features, NeuroFusion restores accurate diagnoses (meningioma 0.92, metastasis 0.75) and improves prose quality while reducing latency 5–6×. A controlled negative result shows that overriding the decoder with a learned diagnosis pin harms performance, and grammar‑constrained decoding yields high schema‑validity (92.3%).
By Khawaja Murad ul Hassan, Ruqiyya Adil, Adil Qayyum, Rida Hassan, Asad Mansoor Khan, Muhammad Usman Akram, Mehran Ebrahimi
CATCH is a conditional 3D diffusion model operating in an invertible Haar-wavelet domain designed to inpaint masked regions in T1‑weighted brain MRI with plausible, tumor‑free tissue while preserving observed anatomy. The model’s denoiser uses noisy target coefficients, voided‑image coefficients, and a signed mask, guided by tumor‑excluded wavelet reconstruction and a hole‑focused loss, and hard compositing ensures observed voxels remain unchanged. Experiments on BraTS data show that a weighted mixture of tumor‑derived, irregular‑blob, and ellipsoidal masks yields the best performance, achieving higher SSIM, PSNR, and lower MSE compared to fixed or random augmentation baselines.
By Simon Winther Albertsen, Hjalte Bjoernstrup, Said Djafar Said, Mostafa Mehdipour Ghazi
The study evaluates the reliability of deep‑ensemble uncertainty for brain tumour segmentation on the BraTS‑GoAT dataset. A 5‑fold cross‑validated nnU‑Net baseline and a 3‑seed deep ensemble were compared for calibration and error detection; the ensemble showed modest gains in calibration on in‑distribution data but the single model’s confidence remained flat while accuracy degraded under synthetic corruptions. Disagreement among ensemble members rose sharply with corruption severity, proving to be a more sensitive indicator of acquisition shift than single‑model confidence.
By Riya Deepak Shet, Chenxi Liang, Le Zhang