arXiv Machine Learning

TRUST: Threshold-Recalibrated Uncertainty-Safe Training for Certified Dismissal in Breast Cancer Screening

The paper introduces TRUST, a threshold‑recalibrated training method that dynamically adjusts the dismissal threshold during training to penalize cancer‑positive images near the dismissal region. Evaluated on NLBS and RSNA datasets, TRUST achieved higher case‑level dismissal rates while maintaining 98% and 95% recall, outperforming a cross‑entropy baseline. External validation on RSNA→NLBS data confirmed improved dismissal rates at both recall targets, demonstrating the effectiveness of closed‑loop threshold‑aware training for selective dismissal in breast cancer screening.

arXiv AI
Aug 5

CorePath: A Breast-Specialized Pathology Foundation Model for Core Needle Biopsy Diagnosis and Risk-Controlled Report Generation

arXiv:2608. 03079v1 Announce Type: cross Abstract: Breast core needle biopsy (CNB) is central to breast cancer diagnosis yet remains challenging because limited tissue sampling, lesion heterogeneity, and subtle morphologic overlap can obscure subtype distinctions.

By Ting Yin, Danning Li, Chen Shu, Xiaoxia Yao, Boyu Fu, Yujing Chang, Tianyu Shi, Mengna Feng, Jie Chen, Jing Fu, Xiuli Xiao, Tianlin Li, Mumin Shao, Jiaxin Bi, Wenchuan Zhang, Xiaoyan Wu, Xiao Han, Zhang Zhang, Yuhao Yi, Hong Bu
arXiv Computer Vision
Sep 4

SafeRestore: Detector-Relative Risk Certificates for Selective Industrial Image Restoration

SafeRestore introduces a framework for certifying when an industrial image restoration should be automatically returned to a detector or require human review. It ranks five restoration candidates using action‑specific fitted scores, selects a threshold gate on tuning data, and evaluates the gate on a separate certification sample with two one‑sided exact binomial bounds—one for evidence‑loss incidents and one for excess‑activation incidents. In a retrospective study of 4,591 Carinthia‑S images, the protocol demonstrates auditable risk‑coverage behavior, with varying pass rates across different policies and morphologies.

By Shaoliang Yang, Jun Wang
arXiv AI
Aug 12

RadFusion: Towards Threshold-Controllable Radiology Report Generation

arXiv:2608. 10505v1 Announce Type: new Abstract: Automated radiology report generation is advancing rapidly in response to the shortage of radiologists, yet unlike a perception model, existing generation models offer no control over the sensitivity-specificity trade-off of their diagnostic content.

By Ying Jin, Noel C. F. Codella, John Corring, Mu Wei, Dinei Florencio, Eric Horvitz
Hugging Face Trending Papers
Aug 11

RadFusion: Towards Threshold-Controllable Radiology Report Generation

Automated radiology report generation is advancing rapidly in response to the shortage of radiologists, yet unlike a perception model, existing generation models offer no control over the sensitivity-specificity trade-off of their diagnostic content. Such control is essential because clinical scenarios diverge: emergency triage prioritizes sensitivity to reduce missed findings, whereas confirmatory interpretation emphasizes specificity to limit unnecessary interventions.

arXiv Machine Learning
1d ago

Fixing a Model That Learned Worse Cancer Means Lower Risk: Monotonic Constraints in Bladder Cancer Recurrence Prediction

In a UK multicentre trial, an unconstrained XGBoost model incorrectly learned that higher tumour stage and carcinoma in situ predicted lower bladder cancer recurrence risk, a finding that conventional metrics such as discrimination, calibration, and SHAP failed to detect. The authors introduced a counterfactual direction test and a monotonic‑constraint framework, which removed the inversion without harming model performance and even outperformed established risk systems. The study demonstrates that such tests should be routine before deploying predictive models in clinical settings.

By Saram Abbas, David Thomas, Naeem Soomro, Rishad Shafik, Rakesh Heer, Kabita Adhikari
arXiv Machine Learning
Sep 24

Benchmarking Active Spot Selection for Cost-Efficient Spatial Transcriptomics

The study benchmarks active spot selection methods against random sampling for spatial transcriptomics, focusing on cost‑efficient data acquisition. Using two public cohorts, the authors simulate multi‑round selection with uncertainty‑based (MC‑dropout, TOD) and diversity‑based (CoreSet, TypiClust) strategies, evaluating performance at 5%, 10%, 30%, and 50% of the spot pool. Results show that none of the active strategies consistently outperforms random sampling across all budgets or evaluation metrics, with performance varying by dataset and metric.

By Zheyu Zhu, Junchao Zhu, Fengbei Liu, Tianyuan Yao, Gelei Xu, John Cannon, Haichun Yang, Yuankai Huo, Mert R. Sabuncu, Ruining Deng