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The paper introduces the first adaptation of the MedSAM2 foundation model for interactive 3D segmentation of interstitial lung disease (ILD) on thoracic CT scans. It evaluates three fine‑tuning strategies and four prompt types—bounding‑boxes, points, lassos, and scribbles—finding that full model fine‑tuning yields the best performance, improving Dice scores by 4.7 percentage points over the baseline. A proof‑of‑concept workflow is presented where MedSAM2 is first initialized with an automatic prior and then refined by radiologist prompts, with all resources released on GitHub.
The paper presents a pragmatic segmentation pipeline for brain metastases in the BraTS 2026 Task 1, using a 5‑fold nnU-Net ResEnc‑L ensemble trained for 1,000 epochs on 1,296 four‑modality cases. A rule‑based post‑processing cascade tuned for the lesion‑wise Dice similarity coefficient (LW‑DSC) improves performance, achieving LW‑DSC scores of 0.733, 0.751, 0.713, and 0.549 on enhancing tumour, tumour core, whole tumour, and resection cavity, respectively. The authors audit each post‑processing stage with a five‑fold out‑of‑fold analysis, confirm two stages as robust, and provide a mechanistic analysis of LW‑DSC, along with thirteen negative results that challenge common intuitions.
The paper presents a segmentation pipeline for brain metastases in both pre‑ and post‑treatment cases using a 5‑fold nnU‑Net ResEnc‑L ensemble trained on 1,296 four‑modality cases. A rule‑based post‑processing cascade improves the lesion‑wise Dice similarity coefficient (LW‑DSC) for enhancing tumour, tumour core, whole tumour, and resection cavity sub‑regions, achieving LW‑DSC scores of 0.733, 0.751, 0.713, and 0.549 respectively on the official validation leaderboard. The authors conduct a five‑fold out‑of‑fold analysis to validate the robustness of each post‑processing stage, provide a mechanistic explanation of LW‑DSC behaviour, and report thirteen negative results that challenge common intuitions, with all code released under Apache‑2.0.
arXiv:2607. 01001v1 Announce Type: cross Abstract: Radiomics is the established approach for CT-based lung cancer phenotyping, yet comparisons with foundation models rarely isolate contributions of feature extractor, classification head, and segmentation choice, or test cross-cohort robustness.
arXiv:2609.01554v1 Announce Type: cross Abstract: Automated lesion segmentation in whole-body PET/CT is complicated by the variety of physiological tracer uptake patterns and by the differing appeara...
arXiv:2606. 28392v1 Announce Type: cross Abstract: Accurate lesion segmentation in PET/CT is critical for oncology, yet remains challenging because physiologic tracer uptake and artifacts can mimic malignant signal.