arXiv Machine Learning

A Multi-Center Benchmark for Abdominal Disease Diagnosis and Report Generation from Non-Contrast CT

arXiv:2606. 16991v1 Announce Type: cross Abstract: Multiphasic contrast-enhanced CT (CECT) is widely used for abdominal lesion characterization, yet it carries inherent risks of contrast-induced nephropathy, escalates acquisition burden, and heavily contributes to radiologist workload.

arXiv AI
Jul 16

Multimodal Assessment of Pancreatic Cancer Resectability Using Deep Learning

arXiv:2607. 13826v1 Announce Type: cross Abstract: Accurate determination of pancreatic ductal adenocarcinoma (PDAC) resectability relies on evaluating how the tumor interacts with major peripancreatic vessels on CT imaging, yet expert assessment often shows substantial variability.

By Vincent Ochs, Christoph Kuemmerli, Florentin Bieder, Julia Wolleb, Joel L. Lavanchy, Julia Ruppel, Jan Liechti, Stephanie Taha-Mehlitz, Christian Andreas Nebiker, Beat Mueller, Giuseppe Kito Fusai, Joerg-Matthias Pollok, Anas Taha, Philippe C. Cattin, Sebastian Staubli
arXiv Computer Vision
Aug 25

Expert-level vision-language foundation model for real-world radiology and comprehensive evaluation

arXiv:2409.16183v2 Announce Type: replace Abstract: Radiology is a vital and complex component of modern clinical workflow and covers many tasks. Recently, vision-language (VL) foundation models in m...

By Xiaohong Liu, Guoxing Yang, Yulin Luo, Jiaji Mao, Xiang Zhang, Haibo Wang, Zhiyang He, Ming Gao, Shanghang Zhang, Jun Shen, Guangyu Wang
arXiv Computer Vision
Sep 24

nnFoundation: 3D Foundation Models for Radiology

nnFoundation introduces complementary convolutional and transformer-based 3D foundation models for radiology, trained on 2.1 million CT, MRI, and PET volumes from 125 datasets. The models are evaluated on 108 tasks—including segmentation, detection, classification, report generation, and image retrieval—under domain shift, low-data, and low-compute scenarios, consistently outperforming prior 3D foundation models and training from scratch. Performance varies by task type, with convolutional models excelling at spatially localized tasks and transformer models at global semantic reasoning, and dynamic alignment with dataset characteristics further enhances transferability.

By Constantin Ulrich Harsy, Tassilo Wald, Karol Gotkowski, Yannick Kirchhoff, Marcel Knopp, Maximilian Rokuss, Elisa Stegmeier, Philipp Schader, Dasha Trofimova, Raphael Stock, Kim-Celine Kahl, Stephen Schaumann, Selen Erkan, David Zimmerer, Stefan Denner, Moritz Langenberg, Sebastian Ziegler, Katharina Eckstein, Maximilian Fischer, Jonathan Suprijadi, B\'alint Kov\'acs, Benjamin Hamm, Anand Deshpande, Dimitrios Bounias, Nico Disch, Shuhan Xiao, Jessica K\"achele, Jan Sellner, Rajesh Baidya, Jeremias Traub, Lars Kr\"amer, Maximilian Zenk, Tim R\"adsch, Stefan Dvoretskii, Robin Peretzke, Jonathan Deissler, Alexandra Ertl, Partha Ghosh, Kris Dreher, Stefan Dinkelacker, Annika Reinke, Evangelia Christodoulou, Numan Saeed, Yoland Savriama, Santiago Estrada, David K\"ugler, Laura Alexandra Daza Barragan, Cristina Isabel Gonzalez Osorio, Jan Peeken, Michael Baumgartner, Marvin Teichmann, Guillaume Chabin, Matthias Kirchler, Valentin Koch, for the ALFA study, Markus Hohenhaus, Dimitri Koslov, Nina Decker, Mohammad Yaqub, Arnd Heuser, Martin Reuter, Julia A. Schnabel, Tobias Heimann, Florin Ghesu, Paul Brachmann, Claus P. Heu{\ss}el, Alexander Radbruch, Gianluca Brugnara, Aditya Rastogi, Martha Foltyn-Dumitru, Heinz-Peter Schlemmer, Ignaz Reicht, Julius C. Holzschuh, Michael Bach, Bram Stieltjes, Kai Schlamp, Lena Maier-Hein, Marco Nolden, Ralf Floca, Paul F. J\"ager, Philipp Vollmuth, Fabian Isensee, Klaus H. Maier-Hein
arXiv Computer Vision
Sep 22

CXR-LT 2026 Challenge: Multi-Center Long-Tailed and Zero Shot Chest X-ray Classification

The CXR‑LT 2026 Challenge introduces a multi‑center, long‑tailed chest X‑ray classification benchmark with over 145,000 radiologist‑annotated images from PadChest and NIH datasets. It defines two core tasks: robust multi‑label classification on 30 known classes and open‑world generalization to 6 unseen rare disease classes. The paper outlines data collection, annotation, solution strategies, and evaluates performance across head‑vs‑tail, calibration, and cross‑center gaps, noting that vision‑language models improve in‑distribution and zero‑shot performance but rare‑finding detection under multi‑center shift remains difficult.

By Hexin Dong, Yi Lin, Pengyu Zhou, Fengnian Zhao, Alan Clint Legasto, Juno Cho, Dohui Kim, Justin Namuk Kim, Mingeon Kim, Sunwoo Kwak, Gabriel Moy\`a-Alcover, Ky Trung Nguyen, Thanh-Huy Nguyen, Ha-Hieu Pham, Huy-Hieu Pham, Huy Le Pham, Nikhileswara Rao Sulake, Aina Tur-Serrano, Ruichi Zhang, Ang Zu, Adam E. Flanders, Zhiyong Lu, Ronald M. Summers, Mingquan Lin, Hao Chen, Yuzhe Yang, George Shih, Yifan Peng
Hugging Face Trending Papers
Jun 24

Disease-Centric Vision-Language Pretraining with Hybrid Visual Encoding for 3D Computed Tomography

Vision-language pre-training (VLP) holds great promise for general-purpose medical AI by leveraging radiology reports as rich textual supervision, yet existing methods struggle with 3D CT imaging due to inefficient visual backbones and coarse semantic alignment. To address these issues, we propose a tailored VLP framework featuring three key components: (1) a CNN-ViT hybrid encoder that replaces ViT's patch embedding with a 3D CNN backbone to efficiently capture local anatomical details while preserving global attention and compatibility with pre-trained cross-modal priors; (2) a disease-level contrastive learning mechanism using learnable query tokens to dynamically extract disease-specific semantics from full reports and align them with corresponding visual features, thereby disentangling distinct diseases within the same anatomical region; and (3) a diagnosis-aware prompt strategy that employs real clinical phrases and aggregated disease prototypes to bridge the pre-training-inference gap and enhance zero-shot diagnostic reliability.

arXiv Machine Learning
Aug 18

AMPLIFAI: A Multiphase CT Dataset for Benchmarking Clinical Reasoning in LI-RADS Assessment of Liver Lesions

The paper introduces AMPLIFAI, the first public dataset of multiphase abdominal CT scans annotated with LI-RADS categories and segmented for three key LI-RADS features: arterial phase hyperenhancement, washout, and enhancing capsule. It outlines the dataset’s composition, curation process, and annotation pipeline following the Datasheets for Datasets format to promote transparency and reproducibility. The dataset aims to support the development of AI models for automated hepatocellular carcinoma diagnosis using the biopsy‑free, imaging‑based LI‑RADs framework.

By Pranav Kulkarni, Nikhil Shah, Amritansh Suryavanshi, Jana Delfino, James Tonascia, Jade Wong-You-Cheong, Barton Lane, Joseph Chirico, Jeffrey D. Hirsch, Ang Li, Heng Huang, Florence X. Doo
arXiv Computer Vision
Sep 15

Designing UNICORN: a Unified Benchmark for Imaging in Computational Pathology, Radiology, and Natural Language

arXiv:2603.02790v2 Announce Type: replace Abstract: Foundation models are changing the way we develop medical artificial intelligence. By learning broadly generalizable features across diverse data m...

By Michelle Stegeman (and on behalf of the UNICORN consortium), Lena Philipp (and on behalf of the UNICORN consortium), Fennie van der Graaf (and on behalf of the UNICORN consortium), Marina D'Amato (and on behalf of the UNICORN consortium), Cl\'ement Grisi (and on behalf of the UNICORN consortium), Luc Builtjes (and on behalf of the UNICORN consortium), Joeran S. Bosma (and on behalf of the UNICORN consortium), Judith Lefkes (and on behalf of the UNICORN consortium), Rianne A. Weber (and on behalf of the UNICORN consortium), James A. Meakin (and on behalf of the UNICORN consortium), Thomas Koopman (and on behalf of the UNICORN consortium), Anne Mickan (and on behalf of the UNICORN consortium), Mathias Prokop (and on behalf of the UNICORN consortium), Ewoud J. Smit (and on behalf of the UNICORN consortium), Fr\'ed\'erique Meeuwsen (and on behalf of the UNICORN consortium), Geert Litjens (and on behalf of the UNICORN consortium), Jeroen van der Laak (and on behalf of the UNICORN consortium), Bram van Ginneken (and on behalf of the UNICORN consortium), Maarten de Rooij (and on behalf of the UNICORN consortium), Henkjan Huisman (and on behalf of the UNICORN consortium), Colin Jacobs (and on behalf of the UNICORN consortium), Francesco Ciompi (and on behalf of the UNICORN consortium), Alessa Hering (and on behalf of the UNICORN consortium)
arXiv Machine Learning
Sep 25

Improving Calibration of Black-Box Radiology AI Using Test-Time Augmentation

The paper presents DualTTA, a model‑agnostic framework that improves the calibration of black‑box radiology AI systems by applying clinically grounded test‑time augmentations (geometric and physics‑inspired 3D CT perturbations) and learning probability‑level aggregation strategies. Without accessing model internals or training data, DualTTA achieved the best overall calibration across pulmonary embolism and intracranial hemorrhage detection tasks, reducing Expected Calibration Error by 54% and 43% respectively. It also outperformed traditional uncertainty estimation methods that require internal model access, such as Temperature Scaling, MC Dropout, and Deep Ensembles.

By Nathan Le, Magdalini Paschali, Arogya Koirala, Andrew Johnston, Zhongnan Fang, David B. Larson, Akshay S. Chaudhari, Camila Gonzalez