arXiv:2607. 20993v1 Announce Type: cross Abstract: Large vision-language models are becoming increasingly dominant in 3D medical image interpretation, but we rarely know which internal units encode clinical findings or where that information lives in the representation.
By Farhad Nooralahzadeh, Lea Bogensperger, Christian Bluethgen, Michael Krauthammer
Vision-language pre-training (VLP) holds great promise for general-purpose medical AI by leveraging radiology reports as rich textual supervision, yet existing methods struggle with 3D CT imaging due to inefficient visual backbones and coarse semantic alignment. To address these issues, we propose a tailored VLP framework featuring three key components: (1) a CNN-ViT hybrid encoder that replaces ViT's patch embedding with a 3D CNN backbone to efficiently capture local anatomical details while preserving global attention and compatibility with pre-trained cross-modal priors; (2) a disease-level contrastive learning mechanism using learnable query tokens to dynamically extract disease-specific semantics from full reports and align them with corresponding visual features, thereby disentangling distinct diseases within the same anatomical region; and (3) a diagnosis-aware prompt strategy that employs real clinical phrases and aggregated disease prototypes to bridge the pre-training-inference gap and enhance zero-shot diagnostic reliability.
arXiv:2606. 03180v1 Announce Type: cross Abstract: Vision-language models (VLMs) for radiology have emerged as a scalable paradigm by leveraging image-report pairs naturally produced in clinical workflows.
By Jonggwon Park, Seongeun Lee, Junhyun Park, Hannah Yun, Hyunwoong Kim, Sohyun Jeong, Hyewon Kang, Byungmu Yoon, Kyoyun Choi
arXiv:2608.28455v1 Announce Type: new
Abstract: Contrastive vision-language learning uses paired chest CT volumes and radiology reports to learn abnormality classifiers without manually annotated lab...
By Huseyin Umut Isik, Mehmet Alp Ozaydin, Sila Kurugol, \c{S}eyda Ertekin
HERO (Histology Encoder for Robust Representation in Oncology) is a ViT‑G/14 pathology foundation model trained with DINO and iBOT objectives and refined using high‑resolution Gram anchoring on a 500‑million‑tile corpus from about 575,000 clinical whole‑slide images. It demonstrates superior robustness to center, scanner, and stain variation compared to other state‑of‑the‑art foundation models, while maintaining competitive performance on tile‑level classification, segmentation, and gene‑expression prediction. Across 39 slide‑level clinical tasks, HERO ranks first on average and achieves the best average rank across six benchmark frameworks under an equal‑weighted analysis.
By Zhi Li (Caris Life Sciences, Irving, TX, United States), Eghbal Amidi (Caris Life Sciences, Irving, TX, United States), Yating Cheng (Caris Life Sciences, Irving, TX, United States), Tyson Dawson (Caris Life Sciences, Irving, TX, United States), Gorkem Can Ates (Caris Life Sciences, Irving, TX, United States), Shuzhen Kuang (Caris Life Sciences, Irving, TX, United States), Norsang Lama (Caris Life Sciences, Irving, TX, United States), Md Ashequr Rahman (Caris Life Sciences, Irving, TX, United States), Zhiying Lu (Caris Life Sciences, Irving, TX, United States), Elisabeth K. Kong (Caris Life Sciences, Irving, TX, United States), Milan Radovich (Caris Life Sciences, Irving, TX, United States), David Spetzler (Caris Life Sciences, Irving, TX, United States), Matthew Oberley (Caris Life Sciences, Irving, TX, United States), George W. Sledge (Caris Life Sciences, Irving, TX, United States), Ming Chen (Caris Life Sciences, Irving, TX, United States)
arXiv:2607. 27154v1 Announce Type: cross Abstract: CT vision-language foundation models have demonstrated promising performance across downstream tasks, but are typically trained with whole-volume representations that dilute fine-grained anatomical signals.
By Roshan Kenia, Stephanie L McNamara, William Lotter
arXiv:2608. 08713v1 Announce Type: cross Abstract: Vision-language models offer a promising path toward automating radiology report generation, but applying them to full 3D CT volumes poses substantial computational challenges.
By Jonathan Suprijadi, Raphael Stock, Moritz Langenberg, David Zimmerer, Kim-Celine Kahl, Stefan Denner, Yannick Kirchhoff, Karol Gotkowski, Maximilian Rokuss, Jeremias Traub, Tassilo Wald, Constantin Ulrich, Klaus Maier-Hein
The paper introduces an unsupervised domain adaptation framework that aligns redundancy-reducing features to enable accurate 3D segmentation of cone-beam CT (CBCT) without target-domain annotations or inference-time adaptation. The method is architecture-agnostic, working with both CNN-based and ViT-based foundation models, and is evaluated on two liver segmentation benchmarks for interventional vascular procedures and radiation therapy. Results show that even large pretrained segmentation networks need explicit feature-space bridging to generalize across diagnostic CT and CBCT, and the proposed approach consistently outperforms existing pretrained foundation models and UDA strategies.
By Gauthier Miralles, Loic Le Folgoc, Vincent Jugnon, Pietro Gori
arXiv:2608.00231v2 Announce Type: replace
Abstract: Volumetric CT vision-language pretraining learns 3D representations from scan-report pairs, but global and anatomy-aware objectives supervise only...
By Guoliang You, Haifan Gong, Xiaomeng Chu
arXiv:2607. 27154v2 Announce Type: replace-cross Abstract: CT vision-language foundation models have demonstrated promising performance across downstream tasks, but are typically trained with whole-volume representations that dilute fine-grained anatomical signals.
By Roshan Kenia, Stephanie L McNamara, William Lotter
arXiv:2510. 15042v3 Announce Type: replace-cross Abstract: In the 3D medical image domain, vision-language pre-training is used to create vision-language encoders (VLEs) that can support radiologists by retrieving patients with similar abnormalities, predicting likelihoods of abnormality, or, with downstream adaptation, generating radiological reports.
By Tassilo Wald, Ibrahim Ethem Hamamci, Yuan Gao, Sam Bond-Taylor, Harshita Sharma, Maximilian Ilse, Cynthia Lo, Olesya Melnichenko, Anton Schwaighofer, Noel C. F. Codella, Maria Teodora Wetscherek, Klaus H. Maier-Hein, Panagiotis Korfiatis, Valentina Salvatelli, Javier Alvarez-Valle, Fernando P\'erez-Garc\'ia
arXiv:2608.24364v1 Announce Type: new
Abstract: Self-supervised pretraining enables transferable representations for medical imaging, yet most CT encoders remain biased toward coarse semantic underst...
By Sebasti\'an Gonz\'alez, Karen Sanchez, Jos\'e M. Saavedra, Marcelo Pizarro, Bernard Ghanem