arXiv AI

ScienceBuddy-PV: A Verifier-Governed Recursive Improvement Protocol for Panvascular Intervention Research

arXiv AI
Oct 15

GUIDE: Computationally Augmented Consensus for Trustworthy Clinical Practice Guidelines

arXiv:2610.16108v1 Announce Type: new Abstract: Maintaining up-to-date clinical practice guidelines (CPGs) is essential for evidence-based medicine, but rapid evidence growth and complex expert conse...

By Yuanfan Lin, Jie Di, Xujin He, Zhenzhe Lin, Jialing Chen, Ruiyang Li, Changyu Zheng, Yuanrui Shang, Weiqin Peng, Jingxi Qin, Xiong Wang, Dongxin Ye, Yining Huang, Guoqiang Li, Andi Xu, Sijia Yu, Ruixin Wang, Yahan Yang, Xiaohang Wu, Duoru Lin, Jingjing Chen, Zhenzhen Liu, Wenben Chen, Haotian Lin
arXiv AI
Sep 11

Safe to Stop? Risk-Constrained Stopping for Sequential Clinical Diagnosis Agents

The paper introduces Cros, a risk‑constrained stopping layer for sequential clinical diagnosis agents that determines when to stop testing and make a diagnosis. Cros combines state‑wise error ranking, policy design on disjoint development splits, and exact tests of selective diagnostic error to provide finite‑sample guarantees. On a MIMIC‑derived abdominal‑pain benchmark, Cros achieves higher state‑error AUROC and lower selective error rates compared to baseline stopping methods, though its performance varies across development resplits.

By Yuexin Wu, Vasile Rus
arXiv Computation and Language
Sep 11

Target leakage, not model class, explains reported accuracy in survey-based cardiovascular screening: a leakage-tiered audit of glass-box and tabular foundation models

The study audited ten different classifiers—including linear, tree‑ensemble, neural, glass‑box, and tabular foundation models—on national health survey data to predict myocardial infarction. By systematically removing features that could cause target leakage, the authors found that all models’ AUROC scores collapsed into a narrow band, indicating that reported high accuracy in prior work was largely due to leakage rather than model sophistication. The glass‑box explainable boosting machine performed comparably to other models while being much faster, and the authors demonstrated that fairness, calibration, and uncertainty can be audited and repaired without sacrificing performance.

By Raad Bin Tareaf, Murad Al-Rajab, Samia Loucif, Samer Ellaham, Cedric Schmitz
arXiv AI
Oct 16

Auditing Escalation Reliability in Healthcare LLM Agents: A Perturbation-Controlled Benchmark of Workflow-State Failures

The paper introduces a benchmark of 400 synthetic healthcare workflow episodes to evaluate large language model (LLM) agents’ reliability in escalating care when evidence is missing or conflicting. It finds that while clean decision accuracy is high (0.97), models miss a large proportion of necessary escalations (32–97%) under uncertainty, and even the largest 9.7B model’s performance drops to 0.78 in conflict scenarios. A workflow-aware controller improves utility and reduces missed escalations, but its effectiveness is limited by lexical generalization failures.

By Zihao Zheng (Washington University in St. Louis), Junyi Yao (Washington University in St. Louis), Baichuan Li (Southern Methodist University), Jiayu Long (Washington University in St. Louis)
arXiv AI
Jul 3

World Feedback for Clinical Agents: Diagnosing RL in FHIR Environments

arXiv:2607. 01470v1 Announce Type: new Abstract: Clinical protocol-execution tasks -- checking a lab value, applying a threshold, placing a correctly structured FHIR order -- are natural candidates for RL from world feedback: once clinical SMEs encode decision logic into a verifier, that verifier grades unlimited rollouts without per-episode annotation.

By Ananya Mantravadi, Harshit Rajgarhia, Prasanna Desikan, Abhishek Mukherji
arXiv AI
Sep 7

What Does Multi-Harness RL Learn? Credit Assignment and Portability in Coding Agents

The study investigates how multi‑harness reinforcement learning (RL) affects coding agents by comparing two grouping strategies—Within (one group per task‑harness pair) and Cross (harnesses pooled within a task)—using a Qwen3‑8B policy trained on frozen task‑harness records from Aider, OpenHands, Qwen Code, and SWE‑agent. Across 24,000 sealed evaluations, the choice of evaluation harness dramatically increases solve rates (from 2.14 % to 9.27 %), while the grouping rule has a negligible effect. Both grouping rules yield similar gains on the same source harness, and Cross‑harness credit does not improve portability beyond Within‑harness credit, suggesting that multi‑harness RL reports should specify grouping boundaries and test on unseen harnesses.

By Chenqian Le, Jiayi Cheng, Qijia He, Runhao Li, Yinghao Li, Xupeng Chen