arXiv:2606. 28692v1 Announce Type: new Abstract: Treatment reasoning underpins every therapeutic decision, integrating disease context, comorbidities, medications, contraindications, and evolving biomedical knowledge to select an appropriate therapy.
By Shanghua Gao, Ayush Noori, Richard Zhu, Curtis Ginder, Zhenglun Kong, Xiaorui Su, Justin Kauffman, Benjamin S. Glicksberg, Joshua Lampert, Ankit Sakhuja, Ashwin Sawant, ATHENA-R1 Evaluation Consortium, David A. Clifton, Noa Dagan, Ran Balicer, Marinka Zitnik
arXiv:2608. 07418v1 Announce Type: new Abstract: In medical education, physicians convert academic knowledge into clinical expertise through residency: years of training across thousands of encounters, with diverse sources of feedback and progressively greater autonomy.
By Valentin Li\'{e}vin, Samuel Schmidgall, Tim Strother, Alex Bijamov, Akshay Goel, Anil Palepu, Chunjong Park, Vahid Balazadeh, Min Woo Sun, Marius Guerard, Justin Chen, Dave Steiner, Vikram Dhillon, Ibrahim Azar, Akhil Mehta, Nicholas Spetsieris, Shilpan Shah, Maen Abdelrahim, Amit Dahiya, Yun Liu, Katherine Chou, Yossi Matias, Avinatan Hassidim, Dale R. Webster, Quoc V. Le, Raia Hadsell, Joelle Barral, Carey Radebaugh, Aleksandra Faust, Shekoofeh Azizi, Mike Schaekermann, Po-Hsuan Cameron Chen, Tao Tu, David Racz, Lin Yang
arXiv:2606. 16149v3 Announce Type: replace Abstract: Rare disease diagnosis depends on expert reasoning that is scarce and difficult to transfer; off-the-shelf large language models (LLMs) rank the correct disease first in only 35.
By Minh-Ha Nguyen, Erica Gray, Bryce A. Schuler, Kevin W. Byram, Chih-Ting Yang, Fan Ma, Hua Xu, Wu-Chen Su, Chao Yan, Wei-Qi Wei, Adam Wright, Lisa Bastarache, Josh Peterson, Lingyao Li, Siyuan Ma, Undiagnosed Diseases Network, Rizwan Hamid, Thomas A. Cassini, Cathy Shyr
arXiv:2510. 21324v2 Announce Type: replace Abstract: Chest X-ray (CXR) plays a pivotal role in clinical diagnosis, and a variety of task-specific and foundation models have been developed for automatic CXR interpretation.
By Jinhui Lou, Yan Yang, Zhou Yu, Zhenqi Fu, Weidong Han, Qingming Huang, Jun Yu
arXiv:2607. 11175v1 Announce Type: new Abstract: The growing ability of large language models and vision language models to jointly interpret and reason over images and text is reshaping medical agents, moving them from task specific predictors toward autonomous systems that perceive, reason, plan, remember, and act in clinical environments.
By Chunzheng Zhu, Lei Tian, Bohan Tan, Ziqi Zhou, Yuxuan Sun, Yijun Wang, Chengchao Lv, Yilin Wen, Yijun He, Jinghao Lin, Yihang Chen, Cheewei Tan, Qianshan Wei, Lei Zhao, Bin Pu, Kenli Li, Yuan Xue, Jianxin Lin
arXiv:2606. 04632v1 Announce Type: new Abstract: Mechanical ventilation for Acute Respiratory Distress Syndrome (ARDS) requires balancing competing physiological goals, including oxygenation, lung protection, and acid-base homeostasis.
By Teqi Hao, Yuxuan Fu, Xiaoyu Tan, Shaojie Shi, Bohao Lv, Yinghui Xu, Xihe Qiu
The paper introduces MACD, a Multi-Agent Clinical Diagnosis framework that enables large language models to self‑learn clinical knowledge through a multi‑agent pipeline of summarization, refinement, and application. MACD is extended into a human‑AI collaborative workflow where multiple diagnostician agents consult iteratively, guided by a judge agent and human oversight. Evaluation on the MIMIC‑MACD cohort shows significant gains in diagnostic accuracy—an average 11.6 percentage‑point improvement over authoritative knowledge for open‑weight LLMs and an 18.3‑percentage‑point boost over physician‑only diagnosis in text‑only vignettes.
By Wenliang Li, Rui Yan, Xu Zhang, Li Chen, Hongji Zhu, Jing Zhao, Junjun Li, Mengru Li, Wei Cao, Zihang Jiang, Wei Wei, Kun Zhang, Shaohua Kevin Zhou
arXiv:2608.21810v1 Announce Type: cross
Abstract: Clinical decision-making is inherently experience-driven: physicians progressively refine their reasoning by synthesizing patient history, multimodal...
By Md Asaduzzaman Jabin, Khoa Le, Lin Zhao, Tianming Liu
arXiv:2606. 15504v1 Announce Type: new Abstract: In recent years, the advances of large language models and autonomous agents have revolutionized the healthcare field, facilitating diagnosis and improving treatment results.
By Qianxue Zhang, Yiming Ren, Shihuan Qin, Xiao Zhang, Liao Zhang, Jinyang Huang, Zhengliang Liu, Chenbin Liu, Hongying Feng, Jingyuan Chen, Yuzhen Ding, Weihang You, Hanqi Jiang, Yi Pan, Yifan Zhou, Junhao Chen, Lifeng Chen, Wei Liu, Tianming Liu, Zengren Zhao, Lian Zhang
arXiv:2601. 03321v3 Announce Type: replace-cross Abstract: Multimodal Large Language Models (MLLMs) have substantially advanced Radiology Report Generation (RRG), yet aligning them through reinforcement learning (RL) remains challenging due to heterogeneous medical supervision.
By Kun Zhao, Guodong Liu, Hui Ji, Siyuan Dai, Pan Wang, Jifeng Song, Chenghua Lin, Liang Zhan, Haoteng Tang
arXiv:2606. 01094v1 Announce Type: new Abstract: Clinical order generation serves as a critical bridge between clinical decision-making and real-world practice, translating medical decisions into concrete and executable orders.
By Ruihui Hou, Ziyue Huai, Chennuo Zhang, Ziyan Liu, Siran Zhao, Yao Yu, Jie Zhai, Tong Ruan
arXiv:2606. 01961v1 Announce Type: new Abstract: Autonomous agents are increasingly expected to support end-to-end medical-AI research workflows, moving beyond isolated prediction tasks or short-form clinical question answering.
By Junqi Liu, Salena Song, Yuhan Wang, Jiawei Mao, Hardy Chen, Xiaoke Huang, Tianhao Qi, Pengfei Guo, Yucheng Tang, Yufan He, Can Zhao, Andriy Myronenko, Dong Yang, Daguang Xu, Yuyin Zhou