arXiv:2609.13543v1 Announce Type: new
Abstract: LLM agents are predominantly benchmarked on short, single-task trajectories, yet real deployments run for hours under contention, surfacing a different...
By Grace Chang Yuan, Xiaoman Zhang, Sung Eun Kim, Luyang Luo, Pranav Rajpurkar
arXiv:2610.15714v1 Announce Type: new
Abstract: Healthcare agents must transform longitudinal clinical evidence into reliable actions through heterogeneous tools and stateful workflows, conditions un...
By Rui Tang, Hongqiu Wang
The paper introduces a benchmark of 400 synthetic healthcare workflow episodes to evaluate large language model (LLM) agents’ reliability in escalating care when evidence is missing or conflicting. It finds that while clean decision accuracy is high (0.97), models miss a large proportion of necessary escalations (32–97%) under uncertainty, and even the largest 9.7B model’s performance drops to 0.78 in conflict scenarios. A workflow-aware controller improves utility and reduces missed escalations, but its effectiveness is limited by lexical generalization failures.
By Zihao Zheng (Washington University in St. Louis), Junyi Yao (Washington University in St. Louis), Baichuan Li (Southern Methodist University), Jiayu Long (Washington University in St. Louis)
arXiv:2607. 28677v1 Announce Type: new Abstract: LLM now pass medical licensing examinations and, in curated cases, can rival physicians at diagnostic reasoning.
By Shayndhan Sivanathan, Shravan Nageswaran, Mehdi Zadem, Ryaan Sultan, Nicolas von Mallinckrodt, Max Solovyev, Alexey Matyushkin, Sumon Sadhu, Gabriele C DeLuca, Sanjeeva Jeyaretna, James Hillis, Manoj Ramachandran, Prakash Jayakumar
arXiv:2607. 18999v1 Announce Type: cross Abstract: Multi-turn medical consultation agents must decide what to ask, adapt to patient responses, and determine when the collected evidence is sufficient.
By Guofeng Zhang, Yizeng Quan, Huaiyi Fang, Jianwei Lv, Jinyao Liu, Xunxu Duan, Lening An, Yu Ouyang, Junfeng Wang
arXiv:2608. 07796v1 Announce Type: new Abstract: Large language models perform strongly on medical knowledge benchmarks, but reliable clinical deployment requires agents to conduct defensible investigations over heterogeneous, longitudinal records: determining what evidence is needed, retrieving and reconciling structured and free-text data, grounding conclusions in verifiable evidence, and deferring cases that cannot be resolved reliably.
By Veronica Chatrath, Bryan Zhu, George Pu, Jingxuan Fan, Apaar Shanker, Varun Ursekar, Anahita Sharma, Jason Qin, Keqi Han, Soham Dinesh Tiwari, Soham Dan, Vijay Kalmath, Yuan Li, Daniel Yue Zhang, Chenguang Wang, Zainab Doctor, Zhijun Yin, Nigam H. Shah, Yuan Xue
arXiv:2606. 28900v1 Announce Type: new Abstract: Doctor agents are moving beyond single-turn answer generation toward evolving clinical decision systems.
By Hui Zhang
The paper introduces Cros, a risk‑constrained stopping layer for sequential clinical diagnosis agents that determines when to stop testing and make a diagnosis. Cros combines state‑wise error ranking, policy design on disjoint development splits, and exact tests of selective diagnostic error to provide finite‑sample guarantees. On a MIMIC‑derived abdominal‑pain benchmark, Cros achieves higher state‑error AUROC and lower selective error rates compared to baseline stopping methods, though its performance varies across development resplits.
By Yuexin Wu, Vasile Rus
arXiv:2607. 18828v1 Announce Type: new Abstract: Readiness stress-testing of medical AI has focused on closed-ended and multimodal benchmarks.
By Koyar Afrasyab
KnowBench is a new benchmark for clinical AI that measures Effort Reduction (ER), the proportion of system-generated clinical work product accepted by clinicians after expert and safety review. The metric is applied uniformly across various administrative tasks—visit notes, billing codes, orders, EHR summarization, patient summaries, and decision support—using the clinician’s review-and-attestation as ground truth. An initial deployment of Knowtex’s models achieved an aggregate ER of 97.99% across more than one million encounters in six months, with specialty-specific ER ranging from 96.8% to 98.9%.
By Jocelyn Kang, Caroline Zhang
EviDx is a new framework for evidence-aware active diagnosis that pairs patient-specific diagnostic environments with a clinical scaffold and an observer-guided runtime harness. The framework constructs interactive environments from raw clinical cases, organizes role-specialized agents and evidence tools, and regulates diagnostic termination by tracking uncertainty and evidence coverage. Experiments demonstrate that EviDx improves diagnostic performance and process stability while revealing model-dependent capability boundaries.
By Lihang Zeng, Shaoting Zhang, Xiaofan Zhang
arXiv:2607. 25485v1 Announce Type: new Abstract: Health AI is evolving from answering questions to agentic systems that converse with patients, reason about health records, and act on their behalf.
By Korosh Vatanparvar, Ashutosh Joshi, Maria Xenochristou, Mohammad Abuzar Hashemi, Prasad Kasu, Deepak Bansal, Daniel Lopez-Martinez, Anchal Nema, Ramya Ganesan, Will Kimbrough, Alex Woody, Yadunandana Rao, Dilek Hakkani-Tur, Wilko Schulz-Mahlendorf