arXiv Machine Learning

A Longitudinal Attribute-Conditioned Neural Network for Modeling Health-State Transition Probabilities in Temporally Irregular Data: The LANTERN Framework

arXiv:2606. 13880v1 Announce Type: new Abstract: Accurate estimation of long-term care transition probabilities is central to disability insurance pricing, reserving, and solvency assessment.

arXiv Machine Learning
Jul 17

A Temporal Machine Learning-Based Time-to-Event Model for Predicting ALS Progression and Healthcare Utilization

arXiv:2607. 14190v1 Announce Type: new Abstract: Amyotrophic lateral sclerosis (ALS) is a progressive and heterogeneous neurodegenerative disease in which predicting clinically meaningful milestones, such as assistive device use, remains challenging.

By Zongliang Yue, Qi Li, Terry Heiman-Patterson, Frank Bearoff, Zhaohui Qin, Huanmei Wu
arXiv AI
Aug 7

Trajectory-guided discharge stratification for heart failure using short-context electronic health record sequence modeling

arXiv:2511. 16839v4 Announce Type: replace-cross Abstract: Purpose: Heart failure (HF) discharge planning depends on identifying patients at risk of deterioration or death, yet accurate prediction from routinely collected electronic health records (EHRs) remains challenging.

By Falk Dippel, Yinan Yu, Annika Rosengren, Martin Lindgren, Christina E. Lundberg, Erik Aerts, Martin Adiels, Helen Sj\"oland
arXiv AI
Sep 1

Scalable Clinical Data Infrastructure and Comparative ML Evaluation for Hospitalisation Risk Prediction in Elderly Patients with Multiple Long-Term Conditions using CPRD

arXiv:2608.29419v1 Announce Type: cross Abstract: Deep learning architectures are increasingly proposed for patient trajectory modeling in electronic health records (EHRs), yet their advantage over s...

By Asra Aslam, Volodymyr Chapman, Maurice M. O'Connell, Aseel S. Abuzour, Michael Abaho, Danushka Bollegala, Gary Leeming, Eduard Shantsila, Andrew Clegg, Lauren E. Walker, Iain Edward Buchan, Samuel D. Relton
Hugging Face Trending Papers
Jun 23

Uncertainty-Aware Longitudinal Forecasting of Alzheimer's Disease Progression Using Deep Learning

Longitudinal modelling of Alzheimer's disease progression is clinically useful only if it can describe not just the most likely next diagnosis, but how a patient may evolve over time and how reliable that forecast is. Most deep learning approaches reduce this problem to single-step classification, treating cognitively normal, mild cognitive impairment, and dementia as flat categories while providing limited insight into how uncertainty accumulates across future visits.

arXiv AI
4d ago

Calibration-First Cross-Cohort Multimodal Temporal Learning for Transferable Asthma-Risk Forecasting

The paper introduces CALIBRA, a calibration-first multimodal temporal learning framework designed for transferable asthma‑risk forecasting across varying patient cohorts and sensor ecosystems. It processes multiple data streams—environmental, pulmonary, symptom, medication, wearable, and context—using dedicated recurrent encoders, a reliability‑conditioned gate, and gradient‑reversal training to mitigate cohort bias. CALIBRA employs a shrinkage‑based hierarchical logistic layer for probability calibration and split conformal prediction for abstention‑capable prediction sets, achieving competitive performance on a semi‑synthetic three‑cohort benchmark with controlled distribution shift.

By Taimoor Ahmad
arXiv Machine Learning
Sep 22

A Patient World Model for Early Forecasting of Digital Health Campaign Outcomes: Capabilities and Limits

The paper introduces a compact patient world model that forecasts digital health campaign outcomes by maintaining a latent state per patient and learning exposure‑conditioned dynamics. Evaluated on a large US campaign dataset, the model predicts new‑to‑brand prescription volume with low relative error (2.9% at week‑4 cutoff) compared to much higher errors from baseline classifiers. The study also shows that dense next‑exposure supervision is crucial for accurate forecasts when conversions are rare and highlights limitations in interpreting exposure‑conditioned rollouts causally.

By Yunlong Wang
arXiv Machine Learning
Jul 30

CalTwin: Towards Calibrated, Shift-Robust Medical World Models via Fisher-Information Regularisation

arXiv:2607. 26752v1 Announce Type: new Abstract: Medical world models aim to learn a latent state of patient or organ physiology and a transition function that forecasts how that state evolves under interventions, supporting downstream tasks from imaging-based diagnosis to digital-twin treatment planning.

By Behraj Khan, Shabir Ahmad, Syed Ahmad Chan Bukhari, Tahir Qasim Syed