The study compares five pre‑trained convolutional neural networks—ResNet50, VGG16, VGG19, MobileNet, and InceptionV3—for melanoma detection using dermatoscopic and histopathological image datasets. Accuracy varied across models and modalities, with ResNet50 achieving the highest scores (84% on HAM10000 and 83% on CR‑AI4SkIN) and InceptionV3 the lowest (71% on ISIC 2018). The results show that a model’s performance on dermatoscopic images does not necessarily predict its performance on histopathological images.
By Wagner Moreno Schmitz, Marco Antonio de Castro Barbosa, Thiago Magalh\~aes Amaral, Dalcimar Casanova, Jefferson Tales Oliva
arXiv:2610.08086v1 Announce Type: new
Abstract: The clinical integration of AI systems in digital dermatology relies heavily on human trust. Clinically interpretable visual concepts can act as interm...
By Linda Wermelinger, Simone Lionetti, Fabian Gr\"oger, Nipun Ranasekara, Philippe Gottfrois, Ludovic Amruthalingam, Labelling Consortium, Marc Pouly, Alexander A. Navarini
arXiv:2609.38560v1 Announce Type: new
Abstract: Mycosis fungoides (MF) is a rare form of cutaneous T-cell lymphoma that is often misdiagnosed in early stages due to its visual similarity to benign in...
By Mohamed Hazem, Tarek Waleed, Omar Khaled, Nada Omar, Mahmoud Raslan, Marwa Mohamed Fawzy, Aya Fahim, Rania M. Mogawer, Ahmed Mourad, Kariman Mansour, Muhammad Rushdi
The paper evaluates how well generalist and dermatology-specific machine learning models perform on diverse skin lesion datasets, including dermoscopic images and smartphone photographs. It benchmarks a range of architectures—general-purpose vision-language models, foundation models, and task-specific dermatology classifiers—under conditions of distribution shift, modality change, and demographic variability. The study quantifies the performance gap between current state‑of‑the‑art models and the robustness needed for safe, equitable clinical deployment.
By Emanoel dos Santos, Kelvin Cunha, Rodrigo Mota, Fabio Papais, Thales Bezerra, Natalia Lopes, Erico Medeiros, Shirley Cruz, Jessica Araujo, Paulo Borba, Tsang Ing Ren
Skin cancer diagnosis from dermoscopic images remains challenging due to high intra-class variability, inter-class similarity, class imbalance, and the limited interpretability of deep learning models. This paper proposes an uncertainty-aware and explainable deep learning framework for multi-class skin lesion classification.
arXiv:2609.24190v1 Announce Type: new
Abstract: Artificial intelligence (AI) has advanced at a rapid pace in recent years. Initially, breakthroughs in large language models caught widespread attentio...
By Rian Dolphin, Laura Knowles
arXiv:2608. 11280v1 Announce Type: cross Abstract: Skin cancer diagnosis from dermoscopic images remains challenging due to high intra-class variability, inter-class similarity, class imbalance, and the limited interpretability of deep learning models.
By Rofiqul Islam, Lilatul Ferdouse
The study examines why dermatology AI models, largely trained on light‑skinned, cancer‑focused images, perform poorly when applied to diverse patient populations. By comparing a cancer‑trained baseline, two dermatology foundation models, and a general‑purpose vision model on tone‑stratified and disease‑shifted datasets, the authors find that disease‑distribution shift, rather than skin‑tone underrepresentation, is the primary cause of generalization failure. Representation analysis shows that cancer‑specialized features lack transferable structure, while dermatology‑pretrained features maintain stronger clustering, and lightweight adaptation with about ten labeled examples per category can recover most performance.
By Nirajan Kunwor, Sanjaya Poudel, Quoc-Huy Trinh, Jahidul Arafat, Sunil Kumar Gaire
arXiv:2609.07180v1 Announce Type: cross
Abstract: Basal Cell Carcinoma (BCC) is the most common type of skin cancer, accounting for nearly 80% of skin cancer di- agnoses. Its optimal clinical managem...
By Alexandros Papadopoulos, Chrysa Episkopou, Ioannis Sarafis, Aimilios Lallas, Anastasios Delopoulos
arXiv:2609.36400v1 Announce Type: cross
Abstract: Deep learning classifiers for dermoscopic skin lesions often reach high in-distribution accuracy while quietly relying on spurious background cues su...
By Youssef Attia, Debasmita Mukherjee
arXiv:2606. 13135v1 Announce Type: cross Abstract: Purpose.
By Elena S. Kozachok, Sergey S. Seregin, Aleksandr V. Kozachok, Ilya P. Latyshev, Oleg I. Samovarov
arXiv:2509.25549v3 Announce Type: replace-cross
Abstract: Choroidal nevi are common benign pigmented lesions in the eye, with a small risk of transforming into melanoma. Early detection is critical t...
By Mohammadmahdi Eshragh, Emad A. Mohammed, Behrouz Far, Ezekiel Weis, Carol L Shields, Sandor R Ferenczy, Trafford Crump