Skin cancer diagnosis from dermoscopic images remains challenging due to high intra-class variability, inter-class similarity, class imbalance, and the limited interpretability of deep learning models. This paper proposes an uncertainty-aware and explainable deep learning framework for multi-class skin lesion classification.
arXiv:2609.36400v1 Announce Type: cross
Abstract: Deep learning classifiers for dermoscopic skin lesions often reach high in-distribution accuracy while quietly relying on spurious background cues su...
By Youssef Attia, Debasmita Mukherjee
arXiv:2609.38560v1 Announce Type: new
Abstract: Mycosis fungoides (MF) is a rare form of cutaneous T-cell lymphoma that is often misdiagnosed in early stages due to its visual similarity to benign in...
By Mohamed Hazem, Tarek Waleed, Omar Khaled, Nada Omar, Mahmoud Raslan, Marwa Mohamed Fawzy, Aya Fahim, Rania M. Mogawer, Ahmed Mourad, Kariman Mansour, Muhammad Rushdi
arXiv:2606.22892v2 Announce Type: replace-cross
Abstract: The clinical diagnosis of skin diseases is susceptible to interference from inter-class similarity of skin lesions, and over-reliance on clin...
By Haibiao Li, Di Lin, Xue Jiang, Weiwei Wu, Yanxi Li, Yugang Chi
The study compares five pre‑trained convolutional neural networks—ResNet50, VGG16, VGG19, MobileNet, and InceptionV3—for melanoma detection using dermatoscopic and histopathological image datasets. Accuracy varied across models and modalities, with ResNet50 achieving the highest scores (84% on HAM10000 and 83% on CR‑AI4SkIN) and InceptionV3 the lowest (71% on ISIC 2018). The results show that a model’s performance on dermatoscopic images does not necessarily predict its performance on histopathological images.
By Wagner Moreno Schmitz, Marco Antonio de Castro Barbosa, Thiago Magalh\~aes Amaral, Dalcimar Casanova, Jefferson Tales Oliva
arXiv:2609.07180v1 Announce Type: cross
Abstract: Basal Cell Carcinoma (BCC) is the most common type of skin cancer, accounting for nearly 80% of skin cancer di- agnoses. Its optimal clinical managem...
By Alexandros Papadopoulos, Chrysa Episkopou, Ioannis Sarafis, Aimilios Lallas, Anastasios Delopoulos
The paper introduces scalable Graph Transformers for classifying healthy versus tumor epithelial cells in whole-slide images of cutaneous squamous cell carcinoma. By constructing a full‑WSI cell graph and incorporating morphological, texture, and neighboring cell class features, the proposed SGFormer and DIFFormer models outperform traditional image‑based methods, achieving balanced accuracies above 85% on single‑WSI tests and 83.6% on multi‑WSI evaluations. The study demonstrates that preserving tissue‑level context through graph representations improves classification of morphologically similar cell types.
By Lucas Sanc\'er\'e, No\'emie Moreau, Katarzyna Bozek
ProtoCAM is an explainable few‑shot learning framework for classifying breast lesions in ultrasound images. It combines mask‑guided feature encoding, prototypical metric learning, and gradient‑based visual explanations to leverage limited annotated data. Evaluated on the BUSI dataset, ProtoCAM achieved a macro F1‑score of 0.910 in a 3‑way 5‑shot setting, outperforming standard supervised CNNs, with ResNet18 reaching 91.65% under 15‑shot conditions.
By Ashkan Ebadi
The study examines why dermatology AI models, largely trained on light‑skinned, cancer‑focused images, perform poorly when applied to diverse patient populations. By comparing a cancer‑trained baseline, two dermatology foundation models, and a general‑purpose vision model on tone‑stratified and disease‑shifted datasets, the authors find that disease‑distribution shift, rather than skin‑tone underrepresentation, is the primary cause of generalization failure. Representation analysis shows that cancer‑specialized features lack transferable structure, while dermatology‑pretrained features maintain stronger clustering, and lightweight adaptation with about ten labeled examples per category can recover most performance.
By Nirajan Kunwor, Sanjaya Poudel, Quoc-Huy Trinh, Jahidul Arafat, Sunil Kumar Gaire
arXiv:2105. 03358v4 Announce Type: replace-cross Abstract: In clinical applications, neural networks must focus on and highlight the most important parts of an input image.
By Soumyya Kanti Datta, Seyed Mohammad Abuzar Hashemi, Sargur N. Srihari, Mingchen Gao
arXiv:2609.22631v1 Announce Type: new
Abstract: Accurate automated interpretation of electrocardio- grams (ECGs) is essential for early detection of cardiac condi- tions such as myocardial infarction...
By Mohammad Sadman Tahsin, Haitham Y. Adarbah, Afzel Noore
arXiv:2608. 14768v1 Announce Type: cross Abstract: Skin lesion classifiers can be confidently wrong on the cases that matter most, so knowing when a prediction should not be trusted is clinically as useful as the prediction.
By Leon Koole, Jiapan Guo, Matias Valdenegro-Toro