Accurate dermatological diagnosis naturally necessitates equitable performance across diverse populations, yet a systematic lack of expertly annotated images, especially for underrepresented skin tones and rare diseases, impedes progress toward measurably fair methods. We introduce cgDDI (Controllable Generation of Diverse Dermatological Imagery), a hybrid framework that (1) synthesizes realistic healthy skin samples without disturbing other input properties, (2) maps single-sample rare lesions onto novel skin-tones and locations non-parametrically, and (3) allows for efficient parametric generation with as few as 10 training samples.
The study compares five pre‑trained convolutional neural networks—ResNet50, VGG16, VGG19, MobileNet, and InceptionV3—for melanoma detection using dermatoscopic and histopathological image datasets. Accuracy varied across models and modalities, with ResNet50 achieving the highest scores (84% on HAM10000 and 83% on CR‑AI4SkIN) and InceptionV3 the lowest (71% on ISIC 2018). The results show that a model’s performance on dermatoscopic images does not necessarily predict its performance on histopathological images.
By Wagner Moreno Schmitz, Marco Antonio de Castro Barbosa, Thiago Magalh\~aes Amaral, Dalcimar Casanova, Jefferson Tales Oliva
arXiv:2608. 11280v1 Announce Type: cross Abstract: Skin cancer diagnosis from dermoscopic images remains challenging due to high intra-class variability, inter-class similarity, class imbalance, and the limited interpretability of deep learning models.
By Rofiqul Islam, Lilatul Ferdouse
Skin cancer diagnosis from dermoscopic images remains challenging due to high intra-class variability, inter-class similarity, class imbalance, and the limited interpretability of deep learning models. This paper proposes an uncertainty-aware and explainable deep learning framework for multi-class skin lesion classification.
arXiv:2606. 13135v1 Announce Type: cross Abstract: Purpose.
By Elena S. Kozachok, Sergey S. Seregin, Aleksandr V. Kozachok, Ilya P. Latyshev, Oleg I. Samovarov
The study examines why dermatology AI models, largely trained on light‑skinned, cancer‑focused images, perform poorly when applied to diverse patient populations. By comparing a cancer‑trained baseline, two dermatology foundation models, and a general‑purpose vision model on tone‑stratified and disease‑shifted datasets, the authors find that disease‑distribution shift, rather than skin‑tone underrepresentation, is the primary cause of generalization failure. Representation analysis shows that cancer‑specialized features lack transferable structure, while dermatology‑pretrained features maintain stronger clustering, and lightweight adaptation with about ten labeled examples per category can recover most performance.
By Nirajan Kunwor, Sanjaya Poudel, Quoc-Huy Trinh, Jahidul Arafat, Sunil Kumar Gaire
arXiv:2608. 15915v1 Announce Type: cross Abstract: Lung cancer remains the leading cause of cancer-related mortality worldwide, while histopathological diagnosis is often affected by inter-observer variability and the substantial workload associated with manual slide examination.
By Hadi Hasan, Safaa Salman, Lama Sleem, Ralph Mouawad, Ali Chehab
arXiv:1812.00877v2 Announce Type: replace-cross
Abstract: Segmentation of skin lesion boundaries in dermoscopic imaging is an important prerequisite step for computer-aided diagnosis of malignant mel...
By Glib Kechyn
InstEditSeg is a generative framework that treats medical segmentation as an instruction-driven image editing task. Instead of producing binary masks, it renders a color-coded overlay on the original image guided by textual instructions, leveraging latent diffusion models to align with natural image distributions and reduce domain gaps. The method incorporates a DINOv3 visual encoder and a multi-scale feature pyramid fused into the diffusion U‑Net, and uses a dual‑branch classifier‑free guidance strategy to lower inference cost, achieving competitive accuracy on polyp and skin lesion datasets while improving cross‑domain generalization and multi‑lesion segmentation.
By Ziquan Liu, Zhewei Zhu, Xuyang Shi
Background/Objectives: Dermoscopic skin lesion classifiers often lose accuracy under domain shift across imaging devices, illumination, and capture artifacts. We study how data augmentation improves the robustness of a binary malignant-versus-non-malignant classifier, with emphasis on out-of-domain (OOD) generalization.
arXiv:2602. 04819v5 Announce Type: replace-cross Abstract: Accurate risk stratification of precancerous polyps during routine colonoscopy screening is a key strategy to reduce the incidence of colorectal cancer (CRC).
By Aqsa Sultana, Rayan Afsar, Ahmed Rahu, Surendra P. Singh, Brian Shula, Brandon Combs, Derrick Forchetti, Vijayan K. Asari
The study evaluates four deep‑learning segmentation architectures—Unet, PSPNet, Linknet, and FPN—paired with six pre‑trained encoders to predict COVID‑19 lesions in CT images. Experiments on three COVID‑19 CT datasets show high accuracy, achieving a maximum binary F1‑score of 98% and multi‑class F1‑scores of 75% and 77%. The work aims to provide a standardized performance benchmark for medical image segmentation and a reference for other imaging scenarios.
By Sarmad Khan, Basim Azam, Arslan Shaukat