arXiv AI

Demonstration of the common dual-channel feature decoupling characteristic of front-door mediation causal inference methods in whole-slice image classification

arXiv:2607. 12376v1 Announce Type: cross Abstract: Causal inference using front door intervention and multi-instance learning (MIL) has advanced the analysis of Whole Slide Images (WSI) in digital pathology.

Hugging Face Trending Papers
Jul 14

Demonstration of the common dual-channel feature decoupling characteristic of front-door mediation causal inference methods in whole-slice image classification

Causal inference using front door intervention and multi-instance learning (MIL) has advanced the analysis of Whole Slide Images (WSI) in digital pathology. These methods adjust feature distributions of subtle evidence sub-images to correctly associate them with WSI-level diagnoses.

arXiv Computer Vision
Sep 28

LadderMIL: Multiple Instance Learning with Coarse-to-Fine Self-Distillation

arXiv:2502.02707v5 Announce Type: replace Abstract: Multiple Instance Learning (MIL) for whole slide image (WSI) analysis in computational pathology often neglects instance-level learning as supervis...

By Shuyang Wu, Yifu Qiu, Ines P. Nearchou, Sandrine Prost, Jonathan A. Fallowfield, Hideki Ueno, Hitoshi Tsuda, David J. Harrison, Hakan Bilen, Timothy J. Kendall
arXiv Machine Learning
Oct 8

Beyond Explanation: Debugging Medical Imaging Models via Concept Intervention

The paper presents a plug‑and‑play framework that uses concept-based interpretation to debug medical imaging models. By aligning a single‑modality encoder with BioMedCLIP, the authors build a Concept Bottleneck Model that allows concept‑level interventions to distinguish causal from spurious features. Experiments on Mayo Clinic ultrasound and CheXpert chest X‑ray data show that these interventions can reliably diagnose model issues and even improve performance through guided fine‑tuning.

By Samrajya Thapa, Daniel J. Quest, Timothy L. Kline, Carrie L. Langstraat, Emanuel C. Trabuco, Wei Le
arXiv Machine Learning
Sep 21

Purification and Regulation: Comorbidity-Aware Multi-Label Few-Shot Learning for Medical Image Classification

The paper introduces Prototype Purification and Regulation (PPR), a multi‑label few‑shot learning framework for medical image classification that addresses two key limitations of existing metric‑based meta‑learning methods. PPR first purifies prototypes by using sample‑level comorbidity scores to highlight disease‑specific features, then regulates inter‑class prototype distances with disease‑level comorbidity statistics to create a comorbidity‑aware embedding space. Experiments on four chest X‑ray datasets, including cross‑domain tests, show that PPR outperforms state‑of‑the‑art methods, improving disease detection and demonstrating robust generalization and clinical applicability.

By Ying-Chih Lin, Po-Chih Kuo, Yong-Sheng Chen