Medical image segmentation is a fundamental task for medical image processing and computer-assisted intervention, yet data imbalance and small lesion detection pose significant challenges. Dice Loss, which measures the overlap between predicted and ground truth regions, is widely used to mitigate these issues.
Region-based loss functions, such as the Dice loss, have established themselves as the de facto standard for highly class- and region-imbalanced segmentation tasks. However, models trained using region-based loss functions are notoriously miscalibrated and typically yield over-confident predictions.
arXiv:2607. 14338v1 Announce Type: cross Abstract: Region-based loss functions, such as the Dice loss, have established themselves as the de facto standard for highly class- and region-imbalanced segmentation tasks.
The paper introduces a Deep Active Contour and Mean Curvature (DACMC) loss function for medical image segmentation. By incorporating mean curvature as a geometric constraint and approximating it with a convolution kernel, the method aims to improve the geometric characterization of segmented regions. Experiments on liver and spleen datasets show that DACMC achieves new state‑of‑the‑art performance across several segmentation benchmarks.
In clinical oncology studies, metastatic cancer is commonly evaluated using "Response Evaluation Criteria in Solid Tumors" (RECIST), in which the diameter of up to five lesions is measured and followed over the course of treatment. However, RECIST shows limited correlation with overall survival.
arXiv:2606. 03069v1 Announce Type: cross Abstract: Generalized segmentation of medical images prevents performance degradation when different imaging devices and clinical protocols are used across multiple domains.
Whole-heart segmentation from CT and MRI is essential for quantitative cardiac image analysis, but remains challenging under multi-center and multi-modality distribution shift. In the CARE whole-heart...
arXiv:2606. 16153v1 Announce Type: cross Abstract: Medical image segmentation plays a critical role in clinical diagnostics, treatment planning, disease monitoring, and neurological disorder identification.
arXiv:2607. 22727v1 Announce Type: cross Abstract: Medical image segmentation models often report high benchmark accuracy under ideal imaging conditions, yet their failures under clinical degradation can be quiet: sensor noise, patient motion, low- resolution acquisition, and contrast variability may all alter model behavior without producing an obvious warning.
The paper introduces MedSegLatDiff, a diffusion-based framework that combines a variational autoencoder (VAE) with a latent diffusion model for medical image segmentation. By compressing images into a low-dimensional latent space, the method reduces noise and speeds up training, while a weighted cross‑entropy loss preserves tiny structures such as small nodules. Evaluated on ISIC‑2018, CVC‑Clinic, and LIDC‑IDRI datasets, MedSegLatDiff achieves state‑of‑the‑art Dice and IoU scores, generates diverse segmentation hypotheses, and produces confidence maps that enhance interpretability and reliability for clinical deployment.
RECIST diameter measurements are widely used for tumor response assessment, but they provide only a limited 2D description of lesion extent. We present LETT-NeXt, a lightweight RECIST-guided model that predicts 3D lesion masks from CT volumes and RECIST markers for the CVPR 2026 Foundation Models for Pan-cancer Segmentation in CT Images competition.
The paper presents a modality‑routed 3D cardiac segmentation pipeline that combines TotalSegmentator‑initialized nnU‑Netv2 models with site‑characterized, label‑preserving appearance augmentation. By analyzing measurable image properties across sites, the authors design a bias‑field plus Bezier augmentation strategy that smooths spatial intensity perturbations and remaps intensities nonlinearly, followed by class‑wise largest‑connected‑component cleanup. On held‑out validation splits, this approach raises CT mean Dice from 0.8350 to 0.9135 and MRI mean Dice from 0.7695 to 0.7830 while reducing HD95, demonstrating improved cross‑site robustness in limited‑data whole‑heart segmentation.
arXiv:2608.23432v1 Announce Type: new Abstract: Accurate organ-at-risk segmentation is essential for radiotherapy planning, but reviewing segmentations is time-consuming and subjective. We investigat...