Medical image segmentation is a fundamental task for medical image processing and computer-assisted intervention, yet data imbalance and small lesion detection pose significant challenges. Dice Loss, which measures the overlap between predicted and ground truth regions, is widely used to mitigate these issues.
Region-based loss functions, such as the Dice loss, have established themselves as the de facto standard for highly class- and region-imbalanced segmentation tasks. However, models trained using region-based loss functions are notoriously miscalibrated and typically yield over-confident predictions.
arXiv:2607. 14338v1 Announce Type: cross Abstract: Region-based loss functions, such as the Dice loss, have established themselves as the de facto standard for highly class- and region-imbalanced segmentation tasks.
In clinical oncology studies, metastatic cancer is commonly evaluated using "Response Evaluation Criteria in Solid Tumors" (RECIST), in which the diameter of up to five lesions is measured and followed over the course of treatment. However, RECIST shows limited correlation with overall survival.
arXiv:2606. 03069v1 Announce Type: cross Abstract: Generalized segmentation of medical images prevents performance degradation when different imaging devices and clinical protocols are used across multiple domains.
arXiv:2606. 16153v1 Announce Type: cross Abstract: Medical image segmentation plays a critical role in clinical diagnostics, treatment planning, disease monitoring, and neurological disorder identification.
arXiv:2607. 22727v1 Announce Type: cross Abstract: Medical image segmentation models often report high benchmark accuracy under ideal imaging conditions, yet their failures under clinical degradation can be quiet: sensor noise, patient motion, low- resolution acquisition, and contrast variability may all alter model behavior without producing an obvious warning.
RECIST diameter measurements are widely used for tumor response assessment, but they provide only a limited 2D description of lesion extent. We present LETT-NeXt, a lightweight RECIST-guided model that predicts 3D lesion masks from CT volumes and RECIST markers for the CVPR 2026 Foundation Models for Pan-cancer Segmentation in CT Images competition.
arXiv:2606. 15370v1 Announce Type: cross Abstract: This work demonstrates a full reproduction and extension of MNet, a hybrid 2D/3D convolutional network designed for anisotropic medical image segmentation.
Medical image segmentation models can achieve strong benchmark performance while remaining sensitive to scanner, protocol, and institutional variation. These context shifts alter image appearance without changing the underlying lesion, allowing models to exploit nuisance cues that Dice and HD95 fail to expose.
arXiv:2608. 12196v1 Announce Type: cross Abstract: Purpose: Deep learning-based medical image segmentation has achieved remarkable success, yet purely data-driven approaches often fail to exploit the rich mathematical structure inherent in medical images.
arXiv:2606. 16868v1 Announce Type: cross Abstract: While federated learning (FL) enables collaborative medical image segmentation without centralizing sensitive data, real-world deployment is frequently complicated by cross-site label imperfections such as contour disagreement, missing or additional structures, and confused labels.
arXiv:2604. 15271v3 Announce Type: replace-cross Abstract: Reliable uncertainty estimation is critical for medical image segmentation, where automated contours feed downstream quantification and clinical decision support.