Region-based loss functions, such as the Dice loss, have established themselves as the de facto standard for highly class- and region-imbalanced segmentation tasks. However, models trained using region-based loss functions are notoriously miscalibrated and typically yield over-confident predictions.
Medical image segmentation is a fundamental task for medical image processing and computer-assisted intervention, yet data imbalance and small lesion detection pose significant challenges. Dice Loss, which measures the overlap between predicted and ground truth regions, is widely used to mitigate these issues.
The paper introduces a Deep Active Contour and Mean Curvature (DACMC) loss function for medical image segmentation. By incorporating mean curvature as a geometric constraint and approximating it with a convolution kernel, the method aims to improve the geometric characterization of segmented regions. Experiments on liver and spleen datasets show that DACMC achieves new state‑of‑the‑art performance across several segmentation benchmarks.
By Xiao-qiang Zhai, Zhi-feng Pang, Peng Zheng, Ze-wen Li, Yan-zhe Hou
arXiv:2607. 22727v1 Announce Type: cross Abstract: Medical image segmentation models often report high benchmark accuracy under ideal imaging conditions, yet their failures under clinical degradation can be quiet: sensor noise, patient motion, low- resolution acquisition, and contrast variability may all alter model behavior without producing an obvious warning.
By Pranav Kaliaperumal, Manisha Kaliaperumal
arXiv:2512. 14937v2 Announce Type: replace-cross Abstract: Gliomas are the most common malignant brain tumors in adults and are among the most lethal.
By Abhijeet Parida, Daniel Capell\'an-Mart\'in, Zhifan Jiang, Nishad Kulkarni, Krithika Iyer, Austin Tapp, Syed Muhammad Anwar, Mar\'ia J. Ledesma-Carbayo, Marius George Linguraru
arXiv:2606. 15837v1 Announce Type: cross Abstract: Deep neural networks (DNNs) frequently fail to generalize to out-of-distribution (OOD) medical images because of variations in scanners and acquisition protocols.
By Jimut B. Pal, Suyash P. Awate