The paper presents a method for estimating segmentation confidence in convolutional neural networks without requiring custom architectures or retraining. It introduces voxel‑based uncertainty estimation that can be integrated into existing pipelines and proposes a novel technique to derive a single confidence score from uncertainty maps. Experiments across various regions of interest and imaging modalities demonstrate that the proposed score predicts segmentation performance on unseen data.
arXiv:2606. 18860v1 Announce Type: cross Abstract: Reliable pixel-level uncertainty quantification holds the potential to transform clinical workflows by enabling high-fidelity longitudinal monitoring and distinguishing true pathological changes from artifacts.
arXiv:2604. 15271v3 Announce Type: replace-cross Abstract: Reliable uncertainty estimation is critical for medical image segmentation, where automated contours feed downstream quantification and clinical decision support.
arXiv:2609.23815v1 Announce Type: new Abstract: Medical image segmentation models typically rely on large amounts of densely annotated volumetric data, limiting their scalability across tasks and ima...
arXiv:2606. 15837v1 Announce Type: cross Abstract: Deep neural networks (DNNs) frequently fail to generalize to out-of-distribution (OOD) medical images because of variations in scanners and acquisition protocols.
The paper introduces Contrastive Uncertainty Learning (CUL), a supervised framework that leverages voxel‑wise predictive uncertainty to guide representation learning for multi‑structure segmentation in lower‑pelvic MRI. Using Monte Carlo Dropout, CUL identifies uncertain voxels and shapes the embedding space so that low‑uncertainty, correctly predicted features become stable while high‑uncertainty or misclassified features are repelled, preventing feature collapse at challenging boundaries. Evaluated on 589 prostate MRI scans with a ViT‑based UperNet decoder, CUL achieves comparable Dice scores to a baseline while significantly reducing surface distance for most structures, and ablation studies confirm the necessity of both uncertainty‑guided sampling and the contrastive objective.
The paper investigates how the CutMix data augmentation technique affects reliability and robustness in semantic segmentation. It evaluates two architectures—CNN-based DeepLabV3+ and transformer-based SegFormer—on both in-domain and out-of-domain data. Results show that CutMix has a minor effect on segmentation accuracy but consistently improves reliability, especially under distribution shifts, by enhancing calibration and uncertainty quality.
The study investigates how confidence intervals (CIs) behave in medical imaging AI by analyzing 24 segmentation and classification tasks with 19 models per task, various metrics, aggregation strategies, and CI methods. It finds that required sample sizes for reliable CIs vary widely, CI behavior depends on performance metrics, aggregation strategy, and problem type, and that different CI methods differ in reliability and precision. The authors provide a decision tree to guide researchers in selecting appropriate CI methods, aiming to support future consensus guidelines on reporting performance uncertainty.
arXiv:2509. 05238v2 Announce Type: replace-cross Abstract: Deep learning (DL) has transformed neuroimaging by delivering state-of-the-art performance with reduced computation times.
arXiv:2608. 14766v1 Announce Type: cross Abstract: Uncertainty estimation is critical for the safe clinical deployment of deep learning in medical image segmentation, with aleatoric uncertainty theoretically designed to capture irreducible data ambiguity.
arXiv:2603. 04024v2 Announce Type: replace-cross Abstract: Ambiguous 3D medical image segmentation often involves boundaries where different expert delineations are non-identical yet clinically plausible.
arXiv:2607. 22727v1 Announce Type: cross Abstract: Medical image segmentation models often report high benchmark accuracy under ideal imaging conditions, yet their failures under clinical degradation can be quiet: sensor noise, patient motion, low- resolution acquisition, and contrast variability may all alter model behavior without producing an obvious warning.
arXiv:2607. 10357v1 Announce Type: cross Abstract: The automatic detection and classification of cardiovascular disease (CVD) from computed tomography (CT) images plays an important role in clinical practice.