arXiv Machine Learning

A Comparative Benchmark of Federated Learning Strategies for Mortality Prediction on Heterogeneous and Imbalanced Clinical Data

arXiv:2509. 10517v3 Announce Type: replace Abstract: Machine learning can predict in-hospital mortality, but data privacy and the statistical heterogeneity of clinical data hamper its use.

arXiv AI
Jul 23

Recovering Clinical Utility Under Differential Privacy: Empirical Validation of Adaptive Federated Aggregation on Heterogeneous Cardiovascular Datasets

arXiv:2607. 19403v1 Announce Type: cross Abstract: Validating federated learning frameworks on real clinical data is an essential step between proof-of-concept demonstrations in controlled synthetic environments and deployment in real multicenter healthcare settings.

By Rodrigo Tertulino, Laercio Alencar, Ricardo Almeida
arXiv Machine Learning
Jun 24

Federated Survival Analysis in Healthcare: A Multi-Model Evaluation on Cross-Institutional Heterogeneous Breast Cancer Data

arXiv:2606. 23871v1 Announce Type: new Abstract: Survival analysis is central to clinical decision-making, yet reliable time-to-event models require large, diverse cohorts that are rarely available at a single institution, while privacy regulations restrict the centralization of patient data.

By Natalia Moreno-Blasco, Anusha Ihalapathirana, Pekka Siirtola, Miguel Fernandez-de-Retana
arXiv AI
Jul 23

SynPre-FL: Synthetic data-driven pretraining integrated Federated Learning training framework

arXiv:2607. 19524v1 Announce Type: cross Abstract: Federated learning (FL) offers a promising approach to privacy-preserving clinical risk prediction, but its deployment remains limited by restricted data sharing, client heterogeneity, class imbalance, and the lack of realistic tabular electronic health record (EHR) benchmarks.

By Akarsh K Nair, Muhammad Arifur Rahman, Nicholas Shopland, Andy Burton, Jun He, Yuan Shen, David Baldwin, Emma O'Dowd, Amna Burzic, Mufti Mahmud, David J. Brown
arXiv Machine Learning
Sep 7

FedDRAW: Federated Dual Reputation Annealing Weighting for Heterogeneous Multi-Institutional Chest Radiograph Classification

FedDRAW introduces a new server‑side aggregation technique for federated learning called Federated Dual Reputation Annealing Weighting. It blends a data‑size prior with cosine similarity between client and global model parameters, using two annealing schedules to shift weight from size to similarity and to gradually relax selectivity. Experiments on 12 simulated client partitions of CheXpert and ChestMNIST datasets show FedDRAW outperforms seven federated baselines in AUC and geometric mean of sensitivity and specificity, with statistically significant results.

By Maryam Moradpour, Anne-Christin Hauschild
arXiv AI
Sep 11

OmniMed-FL: A Robust Multimodal Federated Learning Framework for Clinical Diagnosis

OmniMed‑FL is a multimodal federated learning framework that fuses chest radiographs and synthetic patient notes to classify five clinical conditions. The study benchmarks eight fusion strategies, three initializations, and four missing‑text imputation rules across 3–20 hospital clients under non‑IID Dirichlet partitioning, showing that federated approaches (FedAvg, FedProx, SCAFFOLD‑AdamW) outperform local‑only training. Multimodal fusion consistently improves performance, achieving macro‑F1 scores up to 0.956 on the synthetic corpus and 0.906 on the radiograph corpus.

By Ayush Debnath, Ruelia Saha, Sudip Misra
arXiv AI
Jul 15

Inclusive Federated Learning Through Compliance-Weighted Noise Allocation in Healthcare AI

arXiv:2505. 22108v4 Announce Type: replace-cross Abstract: Background: Federated learning (FL) enables collaborative training of clinical AI models without centralizing patient data, but adoption is limited by privacy concerns, heterogeneous institutional compliance, and resource disparities; standard differential privacy (DP) applies uniform noise to all clients, penalizing well-compliant or under-resourced institutions.

By Santhosh Parampottupadam, Melih Co\c{s}\u{g}un, Sarthak Pati, Maximilian Zenk, Saikat Roy, Dimitrios Bounias, Benjamin Hamm, Sinem Sav, Ralf Floca, Klaus Maier-Hein