The paper introduces a latent dynamical model that captures full‑cycle biventricular cardiac motion from cine MRI using a heart‑rate‑aware neural ODE and a graph‑based mesh autoencoder. It encodes ventricular anatomy and motion as a continuous latent trajectory, with a covariate‑conditioned prior for the end‑diastolic state and a Cox model linking deviations to incident heart failure. In a large UK Biobank cohort, adding the latent score to existing risk equations improved predictive performance, outperforming several established cardiac markers and alternative modeling approaches.
By David Br\"uggemann, Ekaterina Krymova, Firat \"Ozdemir, Jochen von Spiczak, Sebastian Kozerke, Samia Mora, Robert Manka, Mathieu Salzmann, Olga V. Demler
arXiv:2606. 26718v1 Announce Type: new Abstract: Cardiac magnetic resonance imaging (CMR) captures rich spatiotemporal information about ventricular structure and motion, but conventional risk models use only a few image-derived indices from selected cardiac phases.
By David Br\"uggemann, Ekaterina Krymova, Firat \"Ozdemir, Jochen von Spiczak, Sebastian Kozerke, Samia Mora, Robert Manka, Mathieu Salzmann, Olga V. Demler
arXiv:2606. 13188v1 Announce Type: cross Abstract: Building patient-specific cardiac models sits at the heart of precision cardiology, yet getting those models into clinical use keeps running into the same wall: mesh generation is slow, messy, and frustrating.
By Abhishek H S, Akash Ganamukhi, Abhimanyu Suresh, Aditya G Hiremath, Prasad B Honnavalli, Adithya Balasubramanyam
The paper introduces ORBIT, a self‑supervised method for detecting end‑diastolic and end‑systolic cardiac phases in fetal echocardiography without manual annotations. ORBIT learns a latent motion trajectory through registration, enabling orientation‑robust identification of phase transitions across diverse fetal heart positions. Evaluated on normal and congenital heart disease cases, it achieves low mean absolute errors (≈1.9–2.4 frames) and outperforms prior annotation‑free approaches that assume fixed orientations.
By Yingyu Yang, Qianye Yang, Can Peng, Elena D'Alberti, Olga Patey, Aris T. Papageorghiou, J. Alison Noble
arXiv:2610.09185v1 Announce Type: new
Abstract: Cine cardiovascular magnetic resonance (CMR) captures the cardiac cycle as a four-dimensional (4D) sequence, but standard acquisition requires electroc...
By Shiyi Wang, Ruochen Sun, Xiang Li, Peirong Liu, Fangxu Xing
arXiv:2607. 02564v1 Announce Type: cross Abstract: Computational models of the human heart are widely used to study electromechanical and fluid-dynamical cardiac function and to support applications such as in silico clinical trials.
By Francesco Fabbri, Martino Andrea Scarpolini, Paolo Ciancarella, Francesco Tudisco, Roberto Verzicco, Alessandro Ricci, Francesco Viola
The paper presents an anatomy‑aligned surface learning framework for reconstructing patient‑specific 4D myocardial surfaces from sparsely sampled short‑axis cine MRI. By parameterizing epicardial and endocardial surfaces on a shared circumferential‑longitudinal UV domain, the method transforms irregular 3D reconstruction into structured coordinate‑field completion, enabling explicit correspondence across subjects and cardiac phases. Experiments on three public datasets show the approach outperforms mesh‑based and implicit methods, achieving Chamfer distances around 2.6–2.9 mm and preserving ventricular function with small errors in volume and ejection fraction.
By Xiaohan Yuan, Xuan Yang, Qingya Li, Yangang Wang, Lei Li
EchoDiST is an unsupervised framework for estimating myocardial motion in echocardiography, combining self‑distillation joint learning of anatomical segmentation and motion estimation with a diffusion‑conditioned network. The method uses limited anatomical annotations and stochastic perturbations during training, yet requires only a single deterministic forward pass at inference. Evaluated on three datasets, EchoDiST consistently outperforms seven other learning‑based approaches in anatomical alignment, strain assessment, and functional metrics, with statistically significant improvements across cross‑view and cross‑dataset tests.
By Feiyue Qi, Xingyue Wei, Jianwen Luo
Local2Mesh is a spatially localized contour‑to‑mesh framework that reconstructs 3‑D left ventricular geometry from sparse 2‑D cardiac MRI contours without requiring 3‑D mesh annotations. It corrects inter‑slice misalignment through geometry‑aware alignment and routes contour features to template vertices via a plane‑aware Local Router, then jointly uses local and global features to deform a template mesh. Experiments on M&Ms‑2 and ACDC datasets show superior geometric reconstruction, functional estimation, and disease classification compared to existing methods, with strong cross‑dataset generalization.
By Haoyu Wu, Ling Lin, Pascal Lef\`evre, Ruizhe Li, Xiaowu Sun
Graph-based cardiac segmentation with implicit anatomical correspondences provides topological guarantees and population-level analysis capabilities, but models trained on independent frames of image sequences exhibit temporal discontinuities that affect reliable clinical measurements, particularly in cardiac ultrasound. In this work, we introduce self-supervised temporal regularization as a post-training refinement stage that exploits the temporal coherence in image sequences to enforce consistent cardiac segmentation and motion estimation over time, without requiring per-frame annotations.
The paper introduces SV-Cine, a cardiac MRI segmentation framework tailored for single ventricle physiology (SVP). It combines a generative data augmentation pipeline that creates synthetic 3D cardiac meshes and MRI, with a diagnosis-conditioned adaptation of the CineMA foundation model that uses patient-level diagnostic information to improve segmentation. Evaluations on an internal cohort show high Dice scores for left and right ventricles, outperforming nnU-Net, and demonstrate that incorporating diagnosis priors can adapt a pretrained model to specialized SVP tasks.
By Lila Cunge, Yuehong Liu, Hang Xu, Thomas Coudert, Pierangelo Renella, J Paul Finn, William Hsu, Kim-Lien Nguyen
Patient-specific 4D myocardial reconstruction from cine MRI supports quantitative functional assessment, regional motion analysis, and simulation-based modeling. However, routinely acquired short-axis...