arXiv AI

From Raw Segmentations to Simulation-Ready Cardiac Meshes: An Automated Framework for Anatomical Reconstruction and Virtual Cohort Generation

arXiv:2607. 02564v1 Announce Type: cross Abstract: Computational models of the human heart are widely used to study electromechanical and fluid-dynamical cardiac function and to support applications such as in silico clinical trials.

arXiv AI
Jun 12

Transformer-Guided Graph Attention for Direct Cardiac Mesh Reconstruction: A Structural Digital Twin Framework

arXiv:2606. 13188v1 Announce Type: cross Abstract: Building patient-specific cardiac models sits at the heart of precision cardiology, yet getting those models into clinical use keeps running into the same wall: mesh generation is slow, messy, and frustrating.

By Abhishek H S, Akash Ganamukhi, Abhimanyu Suresh, Aditya G Hiremath, Prasad B Honnavalli, Adithya Balasubramanyam
arXiv Computer Vision
Sep 14

SV-Cine: Diagnosis-Conditioned Segmentation of Single Ventricle Physiology via Generative Data Augmentation

The paper introduces SV-Cine, a cardiac MRI segmentation framework tailored for single ventricle physiology (SVP). It combines a generative data augmentation pipeline that creates synthetic 3D cardiac meshes and MRI, with a diagnosis-conditioned adaptation of the CineMA foundation model that uses patient-level diagnostic information to improve segmentation. Evaluations on an internal cohort show high Dice scores for left and right ventricles, outperforming nnU-Net, and demonstrate that incorporating diagnosis priors can adapt a pretrained model to specialized SVP tasks.

By Lila Cunge, Yuehong Liu, Hang Xu, Thomas Coudert, Pierangelo Renella, J Paul Finn, William Hsu, Kim-Lien Nguyen
arXiv AI
Jul 14

A Unified Framework for Comprehensive Cardiac CT Segmentation and Phenotyping: Human-in-the-Loop Data Annotation, Vision Foundation Model Development, Multicenter Evaluation and Clinical Validation

arXiv:2607. 11287v1 Announce Type: cross Abstract: Comprehensive quantification of cardiac structures from computed tomography (CT) remains limited not by data availability but by the scalability of measurements, which makes routine use impractical.

By Pooya Mohammadi Kazaj, Leo Fridolin Weber, Wen Xie, Seyed Amir Ahmad Safavi-Naini, Anselm Stark, Giovanni Baj, Ali Mokhtari, Toshiya Yoshida, Christoph Ryffel, Taishi Okuno, Yoshihiro Akashi, Ronny R. Buechel, Thomas Pilgrim, Waldo Valenzuela, George C. M. Siontis, Xiaowei Xu, Moritz Hundertmark, Stephan Windecker, Christoph Grani, Isaac Shiri
arXiv Computer Vision
Sep 25

Anatomy-Aligned Surface Field Learning for Myocardial Reconstruction from Sparse Short-Axis Cine MRI

The paper presents an anatomy‑aligned surface learning framework for reconstructing patient‑specific 4D myocardial surfaces from sparsely sampled short‑axis cine MRI. By parameterizing epicardial and endocardial surfaces on a shared circumferential‑longitudinal UV domain, the method transforms irregular 3D reconstruction into structured coordinate‑field completion, enabling explicit correspondence across subjects and cardiac phases. Experiments on three public datasets show the approach outperforms mesh‑based and implicit methods, achieving Chamfer distances around 2.6–2.9 mm and preserving ventricular function with small errors in volume and ejection fraction.

By Xiaohan Yuan, Xuan Yang, Qingya Li, Yangang Wang, Lei Li
arXiv Computer Vision
Aug 27

Improving Cross-Site Whole-Heart Segmentation

The paper presents a modality‑routed 3D cardiac segmentation pipeline that combines TotalSegmentator‑initialized nnU‑Netv2 models with site‑characterized, label‑preserving appearance augmentation. By analyzing measurable image properties across sites, the authors design a bias‑field plus Bezier augmentation strategy that smooths spatial intensity perturbations and remaps intensities nonlinearly, followed by class‑wise largest‑connected‑component cleanup. On held‑out validation splits, this approach raises CT mean Dice from 0.8350 to 0.9135 and MRI mean Dice from 0.7695 to 0.7830 while reducing HD95, demonstrating improved cross‑site robustness in limited‑data whole‑heart segmentation.

By Tanish Mudaliar, Justin Li, Daniel Lin, Julianna Vo, Kaitao Liao, Xin Wang, Shu Hu