arXiv:2606. 13188v1 Announce Type: cross Abstract: Building patient-specific cardiac models sits at the heart of precision cardiology, yet getting those models into clinical use keeps running into the same wall: mesh generation is slow, messy, and frustrating.
By Abhishek H S, Akash Ganamukhi, Abhimanyu Suresh, Aditya G Hiremath, Prasad B Honnavalli, Adithya Balasubramanyam
arXiv:2608. 09460v1 Announce Type: new Abstract: Cardiac digital twin research is moving from subject-specific anatomical replicas toward virtual cohorts that represent clinically relevant population subgroups.
By Konstantinos Kevopoulos, Beatrice Moscoloni, Benjamin Alheit, Cameron Beeche, Julio A. Chirinos, Alexander Heinlein, Mathias Peirlinck
arXiv:2606. 03827v1 Announce Type: cross Abstract: In-silico trials of medical devices require the generation of virtual populations of anatomies.
By Shaokun Lan, Haoran Dou, Jinghan Huang, Arezoo Zakeri, Fengming Lin, Zherui Zhou, Jinming Duan, Alejandro F. Frangi
arXiv:2608. 19965v1 Announce Type: cross Abstract: Segmentation of curvilinear anatomical structures in 3D medical images remains challenging due to complex topology, severe class imbalance, weak contrast, and large variations in structure morphology.
By Sidi Mohamed Sid'El Moctar, Nicolas Vitry, H\'el\`ene Bouvrais
The paper introduces SV-Cine, a cardiac MRI segmentation framework tailored for single ventricle physiology (SVP). It combines a generative data augmentation pipeline that creates synthetic 3D cardiac meshes and MRI, with a diagnosis-conditioned adaptation of the CineMA foundation model that uses patient-level diagnostic information to improve segmentation. Evaluations on an internal cohort show high Dice scores for left and right ventricles, outperforming nnU-Net, and demonstrate that incorporating diagnosis priors can adapt a pretrained model to specialized SVP tasks.
By Lila Cunge, Yuehong Liu, Hang Xu, Thomas Coudert, Pierangelo Renella, J Paul Finn, William Hsu, Kim-Lien Nguyen
arXiv:2607. 11287v1 Announce Type: cross Abstract: Comprehensive quantification of cardiac structures from computed tomography (CT) remains limited not by data availability but by the scalability of measurements, which makes routine use impractical.
By Pooya Mohammadi Kazaj, Leo Fridolin Weber, Wen Xie, Seyed Amir Ahmad Safavi-Naini, Anselm Stark, Giovanni Baj, Ali Mokhtari, Toshiya Yoshida, Christoph Ryffel, Taishi Okuno, Yoshihiro Akashi, Ronny R. Buechel, Thomas Pilgrim, Waldo Valenzuela, George C. M. Siontis, Xiaowei Xu, Moritz Hundertmark, Stephan Windecker, Christoph Grani, Isaac Shiri
arXiv:2606. 26764v1 Announce Type: cross Abstract: Developing robust artificial intelligence models for 4D (3D + time) medical imaging is constrained by limited annotated data, inter-device domain shifts, and privacy restrictions.
By Yiheng Cao, Gustavo Andrade-Miranda, Jiatian Zhang, Lingxiao Zhao, Xin Gao
Developing robust artificial intelligence models for 4D (3D + time) medical imaging is constrained by limited annotated data, inter-device domain shifts, and privacy restrictions. To address this, we propose a 4D controllable generative framework for anatomically consistent data augmentation.
The paper presents an anatomy‑aligned surface learning framework for reconstructing patient‑specific 4D myocardial surfaces from sparsely sampled short‑axis cine MRI. By parameterizing epicardial and endocardial surfaces on a shared circumferential‑longitudinal UV domain, the method transforms irregular 3D reconstruction into structured coordinate‑field completion, enabling explicit correspondence across subjects and cardiac phases. Experiments on three public datasets show the approach outperforms mesh‑based and implicit methods, achieving Chamfer distances around 2.6–2.9 mm and preserving ventricular function with small errors in volume and ejection fraction.
By Xiaohan Yuan, Xuan Yang, Qingya Li, Yangang Wang, Lei Li
Patient-specific 4D myocardial reconstruction from cine MRI supports quantitative functional assessment, regional motion analysis, and simulation-based modeling. However, routinely acquired short-axis...
arXiv:2605.08172v2 Announce Type: replace
Abstract: Anatomical mesh segmentation requires models that operate directly on irregular surface geometry while remaining robust to changes in coordinate po...
By Daniel Saragih
The paper presents a modality‑routed 3D cardiac segmentation pipeline that combines TotalSegmentator‑initialized nnU‑Netv2 models with site‑characterized, label‑preserving appearance augmentation. By analyzing measurable image properties across sites, the authors design a bias‑field plus Bezier augmentation strategy that smooths spatial intensity perturbations and remaps intensities nonlinearly, followed by class‑wise largest‑connected‑component cleanup. On held‑out validation splits, this approach raises CT mean Dice from 0.8350 to 0.9135 and MRI mean Dice from 0.7695 to 0.7830 while reducing HD95, demonstrating improved cross‑site robustness in limited‑data whole‑heart segmentation.
By Tanish Mudaliar, Justin Li, Daniel Lin, Julianna Vo, Kaitao Liao, Xin Wang, Shu Hu