arXiv AI

Transformer-Guided Graph Attention for Direct Cardiac Mesh Reconstruction: A Structural Digital Twin Framework

arXiv:2606. 13188v1 Announce Type: cross Abstract: Building patient-specific cardiac models sits at the heart of precision cardiology, yet getting those models into clinical use keeps running into the same wall: mesh generation is slow, messy, and frustrating.

arXiv AI
Jul 7

From Raw Segmentations to Simulation-Ready Cardiac Meshes: An Automated Framework for Anatomical Reconstruction and Virtual Cohort Generation

arXiv:2607. 02564v1 Announce Type: cross Abstract: Computational models of the human heart are widely used to study electromechanical and fluid-dynamical cardiac function and to support applications such as in silico clinical trials.

By Francesco Fabbri, Martino Andrea Scarpolini, Paolo Ciancarella, Francesco Tudisco, Roberto Verzicco, Alessandro Ricci, Francesco Viola
arXiv Computer Vision
Aug 27

Steer the Sampling, Not the Kernel Grid: Geometry-Guided Sampling Operator for Volumetric Segmentation

The paper introduces a geometry‑guided sampling operator that directs feature sampling rather than altering convolution kernels in 3D encoder‑decoder networks. By predicting local orientations and bounded step sizes, the operator samples symmetrically around each voxel, generating compact geometric and boundary cues that improve fine‑structure segmentation. Replacing stride‑1 and stride‑2 operations in a 3D U‑Net yields consistent gains on BraTS, MSD Hepatic Vessel, and TDSC‑ABUS datasets, with better boundary metrics and fewer parameters, and the operator can be integrated into other backbones without architectural changes.

By Sizhe Wang, Himashi Peiris, Zhaolin Chen
arXiv Computer Vision
Sep 14

SV-Cine: Diagnosis-Conditioned Segmentation of Single Ventricle Physiology via Generative Data Augmentation

The paper introduces SV-Cine, a cardiac MRI segmentation framework tailored for single ventricle physiology (SVP). It combines a generative data augmentation pipeline that creates synthetic 3D cardiac meshes and MRI, with a diagnosis-conditioned adaptation of the CineMA foundation model that uses patient-level diagnostic information to improve segmentation. Evaluations on an internal cohort show high Dice scores for left and right ventricles, outperforming nnU-Net, and demonstrate that incorporating diagnosis priors can adapt a pretrained model to specialized SVP tasks.

By Lila Cunge, Yuehong Liu, Hang Xu, Thomas Coudert, Pierangelo Renella, J Paul Finn, William Hsu, Kim-Lien Nguyen
arXiv Computer Vision
Sep 25

Anatomy-Aligned Surface Field Learning for Myocardial Reconstruction from Sparse Short-Axis Cine MRI

The paper presents an anatomy‑aligned surface learning framework for reconstructing patient‑specific 4D myocardial surfaces from sparsely sampled short‑axis cine MRI. By parameterizing epicardial and endocardial surfaces on a shared circumferential‑longitudinal UV domain, the method transforms irregular 3D reconstruction into structured coordinate‑field completion, enabling explicit correspondence across subjects and cardiac phases. Experiments on three public datasets show the approach outperforms mesh‑based and implicit methods, achieving Chamfer distances around 2.6–2.9 mm and preserving ventricular function with small errors in volume and ejection fraction.

By Xiaohan Yuan, Xuan Yang, Qingya Li, Yangang Wang, Lei Li
arXiv Computer Vision
Aug 27

Improving Cross-Site Whole-Heart Segmentation

The paper presents a modality‑routed 3D cardiac segmentation pipeline that combines TotalSegmentator‑initialized nnU‑Netv2 models with site‑characterized, label‑preserving appearance augmentation. By analyzing measurable image properties across sites, the authors design a bias‑field plus Bezier augmentation strategy that smooths spatial intensity perturbations and remaps intensities nonlinearly, followed by class‑wise largest‑connected‑component cleanup. On held‑out validation splits, this approach raises CT mean Dice from 0.8350 to 0.9135 and MRI mean Dice from 0.7695 to 0.7830 while reducing HD95, demonstrating improved cross‑site robustness in limited‑data whole‑heart segmentation.

By Tanish Mudaliar, Justin Li, Daniel Lin, Julianna Vo, Kaitao Liao, Xin Wang, Shu Hu
arXiv AI
Jul 7

CONFLUX: A Latent Diusion Model for 3D Chest-CT Synthesis with RL Post-Training

arXiv:2607. 02998v1 Announce Type: cross Abstract: Controllable generative models of 3D medical images can synthesize volumes with specified clinical attributes, but this demands samples that are simultaneously high-fidelity, natively 3D, and faithful to the requested conditioning.

By Max Van Puyvelde, Halil Ibrahim Gulluk, Wim Van Criekinge, Olivier Gevaert
arXiv AI
Aug 13

A Neighborhood Attention Transformer Network for Enhanced 3D Segmentation of the Left Anterior Descending Artery

arXiv:2608. 12274v1 Announce Type: cross Abstract: Background: Accurate segmentation of the Left Anterior Descending (LAD) artery in 3D free-breathing, non-contrast CT is critical for cardiac dose sparing in thoracic radiotherapy.

By Rafi Ibn Sultan, Chengyin Li, Yiannos Demetriou, Ahmed I. Ghanem, Joshua P. Kim, Justine Cunningham, Hassan Bagher-Ebadian, Dongxiao Zhu, Kundan S. Thind
arXiv AI
Jul 8

CONFLUX: A Latent Diffusion Model for 3D Chest-CT Synthesis with RL Post-Training

arXiv:2607. 02998v2 Announce Type: replace-cross Abstract: Controllable generative models of 3D medical images can synthesize volumes with specified clinical attributes, but this demands samples that are simultaneously high-fidelity, natively 3D, and faithful to the requested conditioning.

By Max Van Puyvelde, Halil Ibrahim Gulluk, Wim Van Criekinge, Olivier Gevaert
arXiv AI
Jun 24

Render-FM: Feedforward Model for Real-time Photorealistic Volumetric Rendering

arXiv:2505. 17338v3 Announce Type: replace-cross Abstract: Photorealistic volumetric rendering of CT scans greatly benefits clinical workflows, yet neural approaches such as Neural Radiance Fields (NeRF) and 3D Gaussian Splatting (3DGS) require prohibitive per-scan optimization (hours for NeRF, about 30 minutes for 3DGS), making them impractical in clinical settings.

By Zhongpai Gao, Benjamin Planche, Meng Zheng, Anwesa Choudhuri, Van Nguyen Nguyen, Terrence Chen, Ziyan Wu
arXiv Computer Vision
Aug 28

DALE-CT: Depth-Aware 2D Slice Encoders Learn an Anatomical World Model of Chest CT

DALE-CT introduces depth‑aware 2D slice encoders that learn an anatomical world model of chest CT scans without 3D or positional supervision. By sampling self‑supervised views across a physical $z$‑axis slab, the encoder captures how anatomy changes between neighboring slices, enabling it to recover slice ordering and distinguish slices by anatomy alone. The model, trained on a large 287k‑scan corpus, achieves state‑of‑the‑art performance on CT‑RATE and is released with full code and evaluation tools.

By Evan W. Damron, Mahmut S. Gokmen, Mitchell A. Klusty, Caroline N. Leach, Emily B. Collier, V. K. Cody Bumgardner