arXiv:2608. 11280v1 Announce Type: cross Abstract: Skin cancer diagnosis from dermoscopic images remains challenging due to high intra-class variability, inter-class similarity, class imbalance, and the limited interpretability of deep learning models.
Acne vulgaris affects most adolescents and many adults. Accurate severity grading guides treatment, monitoring, and clinical trial endpoints, but manual assessment using the Investigator's Global Assessment or Hayashi criteria is limited by inter-rater variability and inconsistent imaging conditions.
Skin cancer diagnosis from dermoscopic images remains challenging due to high intra-class variability, inter-class similarity, class imbalance, and the limited interpretability of deep learning models. This paper proposes an uncertainty-aware and explainable deep learning framework for multi-class skin lesion classification.
The study examines why dermatology AI models, largely trained on light‑skinned, cancer‑focused images, perform poorly when applied to diverse patient populations. By comparing a cancer‑trained baseline, two dermatology foundation models, and a general‑purpose vision model on tone‑stratified and disease‑shifted datasets, the authors find that disease‑distribution shift, rather than skin‑tone underrepresentation, is the primary cause of generalization failure. Representation analysis shows that cancer‑specialized features lack transferable structure, while dermatology‑pretrained features maintain stronger clustering, and lightweight adaptation with about ten labeled examples per category can recover most performance.
The paper introduces MIFR, a modality‑invariant and fair representation framework for skin disease classification that jointly processes clinical photographs and dermoscopic images using ViT‑based encoders. It employs a five‑component multi‑objective loss to balance classification accuracy, fairness across skin tones, class alignment, and modality invariance. Experiments on paired and external datasets demonstrate competitive predictive performance and fairness, with t‑SNE visualizations confirming alignment of embeddings from different modalities.
arXiv:2609.36400v1 Announce Type: cross Abstract: Deep learning classifiers for dermoscopic skin lesions often reach high in-distribution accuracy while quietly relying on spurious background cues su...
Skin diseases represent a major global public health burden, yet machine learning tools developed to assist in their diagnosis suffer from two critical limitations: reliance on only one modality for d...
CG-HAF is a global‑local fusion framework for ordinal acne severity grading that explicitly combines holistic facial severity probabilities with structured lesion‑burden descriptors such as lesion count, detection confidence, and lesion area. The model uses a lightweight, interpretable classifier to produce the final grade, achieving statistically significant improvements over global‑evidence‑only baselines, especially for severe cases. Cross‑dataset testing reveals that strong performance within a dataset does not automatically transfer, largely due to mismatched grading criteria rather than detection failures.
arXiv:2609.38560v1 Announce Type: new Abstract: Mycosis fungoides (MF) is a rare form of cutaneous T-cell lymphoma that is often misdiagnosed in early stages due to its visual similarity to benign in...
The study compares five pre‑trained convolutional neural networks—ResNet50, VGG16, VGG19, MobileNet, and InceptionV3—for melanoma detection using dermatoscopic and histopathological image datasets. Accuracy varied across models and modalities, with ResNet50 achieving the highest scores (84% on HAM10000 and 83% on CR‑AI4SkIN) and InceptionV3 the lowest (71% on ISIC 2018). The results show that a model’s performance on dermatoscopic images does not necessarily predict its performance on histopathological images.
LENS‑GRF is a permutation‑invariant lesion evidence network that uses a Set‑Transformer and gated residual fusion to combine global facial context with localized lesion patches for four‑class acne severity grading. The framework integrates adaptive facial skin segmentation, a Vision Transformer prior, and a lesion set transformer that encodes spatial geometry, with a gating mechanism that modulates local residual contributions. In experiments on ACNE04 and PLSBRACNE01, the fully automated model achieved 80.82% accuracy, while using ground‑truth lesion annotations raised accuracy to 95.89% and a Quadratic Weighted Kappa of 0.9753; zero‑shot evaluation on the full cohort yielded 35.00% accuracy versus 42.50% for a global baseline, and oracle analyses on a 148‑subject cohort showed improved accuracy and QWK up to 47.97% and 0.5799.
arXiv:2609.07180v1 Announce Type: cross Abstract: Basal Cell Carcinoma (BCC) is the most common type of skin cancer, accounting for nearly 80% of skin cancer di- agnoses. Its optimal clinical managem...