arXiv AI

Interpretable Deep Learning Models for Breast Cancer Diagnosis Using Medical Imaging

The study evaluates ten ImageNet‑pretrained deep learning models for classifying benign versus malignant breast cancer in the BreakHis histopathology dataset, using a patient‑level split. DenseNet121 achieved the highest performance with 99.4% accuracy and an AUC‑ROC of 0.999, outperforming all other models (p < 0.001). Explainability methods (Grad‑CAM, LIME, Integrated Gradients, LRP) consistently identified nuclei‑rich and glandular regions as key diagnostic features, demonstrating that transfer learning combined with explainable AI can produce accurate and interpretable breast cancer diagnostic tools.

arXiv AI
Sep 17

A Lightweight CNN Integrated Compact Convolutional Transformer for Multi-Scale Feature Learning and reducing computational complexity for breast cancer mammography image detection and classification

The paper presents a lightweight CNN‑integrated Compact Convolutional Transformer (CCT) designed for multi‑scale feature learning in breast cancer mammography. With only 250,435 parameters, the model achieved 99‑100% accuracy across three datasets using 5‑fold cross‑validation, demonstrating robust generalization. Explainable AI components were added to clarify the classification process, aiming to increase clinical trust in resource‑constrained settings.

By Md Taimur Ahad (Department of Management North South University, Dhaka, Bangladesh), Ainuddin Ahmed (Department of Management North South University, Dhaka, Bangladesh)
arXiv AI
Sep 15

ProtoCAM: Interpretable Few-Shot Mask-Guided Prototypical Learning for Breast Lesion Classification in Ultrasound Imaging

ProtoCAM is an explainable few‑shot learning framework for classifying breast lesions in ultrasound images. It combines mask‑guided feature encoding, prototypical metric learning, and gradient‑based visual explanations to leverage limited annotated data. Evaluated on the BUSI dataset, ProtoCAM achieved a macro F1‑score of 0.910 in a 3‑way 5‑shot setting, outperforming standard supervised CNNs, with ResNet18 reaching 91.65% under 15‑shot conditions.

By Ashkan Ebadi
arXiv Machine Learning
Jul 14

BiLoG-Net: A Bi-Context Location-Guided Network for Breast Mass Segmentation and Malignancy Classification in Mammography

arXiv:2607. 10188v1 Announce Type: cross Abstract: Breast cancer remains the most commonly diagnosed malignancy among women worldwide, yet accurate detection and characterization of breast masses in mammography remain challenging due to subtle intensity variations, heterogeneous tissue densities, and indistinct lesion boundaries that complicate radiological interpretation.

By Abu Fatema Mohammad Abdun Noor, Md Imam Ahasan, Md Samiul Ahasan, Kah Ong Michael Goh, S M Hasan Mahmud, Raihana Zannat
arXiv AI
Jul 7

An Interpretable Deep Learning Framework for Discovery and Clinical Validation of Deep Radiomic Signatures in Tumor Classification

arXiv:2607. 03593v1 Announce Type: cross Abstract: Imaging signatures are quantitative features extracted from medical images that provide clinically meaningful information for tumor diagnosis, characterization, prognosis, and treatment planning.

By Chengkun Sun, Jinqian Pan, Renjie Liang, Zhengkang Fan, Xin Miao, Yi Guo, Mei Liu, Muxuan Liang, Russell Terry, Jie Xu
Hugging Face Trending Papers
Jul 3

An Interpretable Deep Learning Framework for Discovery and Clinical Validation of Deep Radiomic Signatures in Tumor Classification

Imaging signatures are quantitative features extracted from medical images that provide clinically meaningful information for tumor diagnosis, characterization, prognosis, and treatment planning. Although deep learning has shown great potential for imaging signature discovery, its limited interpretability remains a major barrier to clinical adoption.

arXiv Computer Vision
Sep 18

Performance of Machine Learning Classification in Sonomammogram Images using BI-RADS

This study evaluates the classification accuracy of six modern deep‑learning architectures—VGG19, ResNet50, GoogleNet, ConvNeXt, EfficientNet, and Vision Transformers—on breast ultrasound images categorized by BI‑RADS. Using 2,945 training images and 936 validation images from 1,540 patients, the models were tested in full fine‑tuning, linear evaluation, and training‑from‑scratch settings. The best performance was achieved with full fine‑tuning, yielding 76.39 % accuracy and a 67.94 % F1 score.

By Malitha Gunawardhana, Norbert Zolek
arXiv Computer Vision
Aug 27

Less Contouring, More Accuracy: Lesion-Guided ROI Deep Learning for Ovarian Ultrasound Classification

The study evaluates lesion‑guided region‑of‑interest (ROI) deep learning for ovarian ultrasound classification, comparing it to global image, lesion contour, and contour‑based radiomics approaches across two public datasets. Using four deep‑learning architectures, the lesion‑guided ROI strategy achieved the highest accuracy (93.10% on MMOTU and 97.56% on OUD) with an AUC of 0.99, while requiring less annotation effort than contour‑based methods.

By Mehran Ahmad, Ali Abbasian Ardakani, Afshin Mohammadi, Alisa Mohebbi, Gernot Kronreif, Sepideh Hatamikia
arXiv AI
Aug 17

CMCNet: Aligning Ultrasound Image Embeddings with Textual TI-RADS Representations for Fine-Grained Thyroid Classification

arXiv:2608. 13939v1 Announce Type: cross Abstract: Ultrasound is the primary imaging modality for assessing thyroid nodules, and the ACR TI-RADS framework standardizes diagnosis through five ultrasound feature categories that are aggregated into five risk levels (TR1-TR5).

By Bingxin Yu, Xueli Wang, Jerry Zhou, Wenyan Wang, Li Wen, Lan Huang, Xin Feng, Fengfeng Zhou, Kewei Li