arXiv:2607. 05462v2 Announce Type: replace-cross Abstract: As AI agents are incorporated into life science workflows, the capabilities that speed discovery might also enable misuse.
By Edwin H. Wintermute, Harmon Bhasin, Christina M. Agapakis, Dianzhuo Wang, Evan Seeyave, Arjun Banerjee, Daniel Fulop, Matthew C. Watson, Adam J. Meyer, Sandrine Boissel, Jens H. Kuhn, Rishi Jain, Noah D. Taylor, Helena Shomar, Patrick M. Boyle, Kenny Workman
arXiv:2607. 05462v1 Announce Type: cross Abstract: As AI agents are incorporated into life science workflows, the capabilities that speed discovery might also enable misuse.
By Edwin H. Wintermute, Harmon Bhasin, Christina M. Agapakis, Dianzhuo Wang, Evan Seeyave, Arjun Banerjee, Daniel Fulop, Matthew C. Watson, Adam J. Meyer, Sandrine Boissel, Jens H. Kuhn, Rishi Jain, Noah D. Taylor, Helena Shomar, Patrick M. Boyle, Kenny Workman
arXiv:2606. 11150v1 Announce Type: new Abstract: Large language models (LLMs) are rapidly acquiring capabilities relevant to biological research, from literature synthesis to interpretation of experimental data.
By Andrew Bo Liu, Samira Nedungadi, Bryce Cai, Alex Kleinman, Harmon Bhasin, Seth Donoughe
BaseCamp is an agentic AI framework that automates the decision layer of DNA sequencing pipelines by deploying six specialized AI agents for tasks such as sample intake, quality control, alignment, variant calling, annotation, cross‑stage monitoring, and reporting. The agents rely on established bioinformatics tools for actual sequence analysis, while using fine‑tuned, domain‑specialized large language models to select, configure, and interpret these tools’ outputs, ensuring reproducibility and local data privacy. Evaluation demonstrates that the agents’ configurations align with expert practice, provide an explicit filtering ledger for traceability, and detect anomalies that traditional monitoring may miss.
By Eranga Bandara, Xueping Liang, Asanga Gunaratna, Tharaka Hewa, Abdul Rahman, Peter Foytik, Safdar H. Bouk, Sachini Rajapakse, Isurunima Kularathna, Pramoda Karunarathna, Chalani Rajapakse, Ng Wee Keong, Kasun De Zoysa, Amin Hass, Wathsala Herath, Ross Gore, Ravi Mukkamala, Nihal Siriwardanagea, Gihan Siriwardanagea, Aruna Withanage, Nilaan Loganathan, Sachin Shetty
arXiv:2609.16213v1 Announce Type: new
Abstract: Artificial intelligence is reshaping biological research across an increasingly connected digital-to-physical workflow. General-purpose large language...
By Candace S. Y. Chan, Aris Karatzikos, Ilias Georgakopoulos-Soares
arXiv:2606. 13602v1 Announce Type: new Abstract: We introduce EpiBench, a verifiable benchmark for short-horizon epigenomics analysis.
By Harihara Muralidharan, Reema Baskar, Soo Hee Lee, Tim Proctor, Kenny Workman
arXiv:2607. 13411v1 Announce Type: cross Abstract: Clinical AI models can expose patients to harm when adversarial vulnerabilities go undetected, yet formal security auditing requires statistical expertise, specialized tools, and significant time.
By Michael O. Eniolade
arXiv:2601. 21800v4 Announce Type: replace Abstract: We introduce BioAgent Bench, an evaluation suite designed for measuring the performance and robustness of AI agents in common bioinformatics tasks.
By Dionizije Fa, Marko Culjak, Bruno Pandza, Mateo Cupic
arXiv:2606. 19899v1 Announce Type: cross Abstract: This paper addresses a rapidly emerging policy challenge: how to generate and interpret credible evidence about the biological capabilities and risks of AI scientists, or agentic AI systems capable of autonomously or collaboratively performing multi-step scientific tasks.
By Patricia Paskov, Jeffrey Lee, Kyle Brady, Alyssa Worland
OpenDiscoveryTrace is a public dataset of 558 complete AI scientific agent trajectories that records the reasoning process—thoughts, tool calls, observations, errors, revision triggers, and confidence—across 124 scientific tasks in drug discovery, materials science, genomics, and literature analysis. The dataset includes seven models (three frontier models and four open‑weight models) and 60 live‑retrieval variants, providing a balanced view of performance and error patterns. Pilot analysis shows that process traces reveal behavioral differences invisible to output‑only evaluation, such as differing error rates and types among frontier models.
By Aayam Bansal, Keertan Balaji
The paper audits a commercial non‑generative System‑1 model on biosecurity‑relevant benchmarks, evaluating accuracy, calibration, error detection, selective prediction, and sensitivity to answer‑option order. It finds that the model’s accuracy varies strongly by task, is reasonably well calibrated when the vendor’s uncertainty field is interpreted correctly, and that option order can cause significant prediction changes—averaging across rotations improves accuracy. The study also shows that applying averaging only to low‑confidence items recovers most of the gain at a lower cost.
By Kimon Antonios Provatas, Ilias Georgakopoulos-Soares
arXiv:2607. 11084v1 Announce Type: new Abstract: Agentic research systems are emerging as a new paradigm for coordinating scientific workflows beyond isolated model inference, code generation, or statistical analysis.
By Eddie Huang (NVIDIA AI Technology Center, NVIDIA Corporation), Ken Liao (NVIDIA AI Technology Center, NVIDIA Corporation), Iven Fu (NVIDIA AI Technology Center, NVIDIA Corporation), Yang-Hsien Lin (NVIDIA AI Technology Center, NVIDIA Corporation), Chao-Shun Zhan (NVIDIA AI Technology Center, NVIDIA Corporation), Andy Liao (NVIDIA AI Technology Center, NVIDIA Corporation), Virginia Chen (NVIDIA AI Technology Center, NVIDIA Corporation), Johnson Sun (NVIDIA AI Technology Center, NVIDIA Corporation), Pika Wang (NVIDIA AI Technology Center, NVIDIA Corporation), Richard Huang (NVIDIA AI Technology Center, NVIDIA Corporation), Jiun-Cheng Jiang (NVIDIA AI Technology Center, NVIDIA Corporation), Ting-Yuan Liu (Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, Master Program for Digital Health Innovation, China Medical University, Taichung, Taiwan), Hsing-Fang Lu (Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan), Ray Y. Lee (AI-Driven Genomic Medicine and Drug Discovery Lab, China Medical University Hospital, Taichung, Taiwan), Chi-Chou Liao (Department of Medical Research, China Medical University Hospital, Taichung, Taiwan), Simon See (NVIDIA AI Technology Center, NVIDIA Corporation), Fuu-Jen Tsai (Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan)