arXiv AI

BioSecBench-Refusal: A paired metric for performance and alignment in agentic biosecurity risk assessment

arXiv:2607. 05462v2 Announce Type: replace-cross Abstract: As AI agents are incorporated into life science workflows, the capabilities that speed discovery might also enable misuse.

arXiv AI
Jul 8

Evaluating calibrated refusal and safe usefulness in dual-use biology settings

arXiv:2607. 05462v1 Announce Type: cross Abstract: As AI agents are incorporated into life science workflows, the capabilities that speed discovery might also enable misuse.

By Edwin H. Wintermute, Harmon Bhasin, Christina M. Agapakis, Dianzhuo Wang, Evan Seeyave, Arjun Banerjee, Daniel Fulop, Matthew C. Watson, Adam J. Meyer, Sandrine Boissel, Jens H. Kuhn, Rishi Jain, Noah D. Taylor, Helena Shomar, Patrick M. Boyle, Kenny Workman
arXiv AI
Jun 19

Measuring Biological Capabilities and Risks of AI Agents

arXiv:2606. 19899v1 Announce Type: cross Abstract: This paper addresses a rapidly emerging policy challenge: how to generate and interpret credible evidence about the biological capabilities and risks of AI scientists, or agentic AI systems capable of autonomously or collaboratively performing multi-step scientific tasks.

By Patricia Paskov, Jeffrey Lee, Kyle Brady, Alyssa Worland
Hugging Face Trending Papers
Jul 20

An Early Warning of Emerging Biosecurity Risks in Frontier LLMs

Frontier large language models (LLMs) are increasingly integrated into scientific workflows, yet their growing biological capabilities may outpace current safeguards. To assess the biological risks of frontier models, we develop Intern-BioBreaker, a specialized bio-red-teaming model, together with an integrated computational-to-physical framework that couples model-level stress testing with wet-lab validation.

arXiv AI
Aug 5

A Blind Spot in Alignment: Quantifying Biosecurity Risks in Large Language Models

arXiv:2608. 02684v1 Announce Type: cross Abstract: Large Language Models (LLMs) are accelerating biological research, yet this same capability poses a critical biosecurity threat: models that assist in protein engineering can equally be prompted to generate predicted toxin-like sequences, potentially lowering the barrier to biological misuse.

By Shu Quan, Tianfang Hao, Sitong Fang, He Geng, Jiayi Zhou, Boyuan Chen, Kaile Wang, Donghai Hong, Juntao Dai, Yaodong Yang, Jiaming Ji
arXiv AI
23h ago

Traceable Trust for action-ready artificial intelligence in bioscience

arXiv:2608. 17997v1 Announce Type: cross Abstract: Artificial intelligence (AI) is becoming part of the working infrastructure of the biosciences.

By Huayu Xin, Yizhi Cai, Mukilan Deivarajan Suresh, Gavin Michael Farrell, Iwona Gajda, Charlie Harrison, Conor Houghton, Mato Lagator, Yang Lu, Virginia Portillo, Reyer Zwiggelaar, Sebastian Lobentanzer
arXiv AI
Jun 12

Muse Spark Safety & Preparedness Report

arXiv:2606. 12429v1 Announce Type: cross Abstract: Muse Spark is the latest large language model developed by Meta.

By Cristina Menghini (Sail), Peter Ney (Sail), Hamza Kwisaba (Sail), Zifan (Sail), Wang, Miles Turpin, Felix Binder, Jean-Christophe Testud, Aidan Boyd, Nathaniel Li, Ivan Evtimov, Klaudia Krawiecka, Arman Zharmagambetov, Jeremy Kritz, Alexander R. Fabbri, Daniel Song, Jinpeng Miao, Joonas Hjelt, Meghna Ramani, Leona Lan, Reza Aghajani, Joanna Bitton, Mahesh Pasupuleti, Devin Norder, Khalid El-Arini, Paridhi Singh, V\'itor Albiero, Sahana CB, Rashnil Chaturvedi, Elahe Dabir, Edoardo Debenedetti, Jim Gust, Ziwen Han, Kat He, Sean Hendryx, Lifeng Jin, Polina Kirichenko, Sandra Lefdal, Kenneth Li, Asad Liaqat, Inna Lin, Despoina Magka, Neal Mangaokar, Ishita Mediratta, Zach Miller, Smitha Milli, Niloofar Mireshghallah, Saba Nazir, Hung Nguyen, Maximilian Nickel, Kelvin Niu, Kerem Oktar, Bhargavi Paranjape, Parth Pathak, Maya Pavlova, Emmanuel Ramirez, David Renardy, Candace Ross, Yasha Sheynin, Claudia Shi, Shivam Singhal, Evangelia Spiliopoulou, Rakshith Sharma Srinivasa, Jamelle Watson-Daniels, Spencer Whitman, Adina Williams, Chen Xing, Andy Zou, Tommy Ma, Siqi Deng, James Beldock, Prashant Ratanchandani, Kate Plawiak, Taesung Lee, Ryan Victory, Lindsay Hundley, Rachad Alao, Himaghna Bhattacharjee, Jianfeng Chi, Gary Frost, Pegah Ghahremani, Niki Howe, Yuheng Huang, Saeed Jahed, Hannah Korevaar, Trang Le, Zhe Liu, Jinghong Luo, Qin Lyu, Nina Mehrabi, Abraham Montilla, Chirag Nagpal, Cyrus Nikolaidis, Rajvardhan Oak, Manoj Ravi, Vidya Sarma, Aman Shankar, Alana Shine, Eric Michael Smith, Mariana Tandon, Michael Tontchev, Caoyu Wang, Zihan Wang, Corinne Wong, Zheng Wu, Hongyuan Zhan, Justin Zhao, Zexuan Zhong, Chengxu Zhuang, Tristan Goodman, Ayaz Minhas, Harrison Rudolph, Victoria Jeffries, Ingrid Dickinson, Alex Vaughan, Lauren Deason, Kamalika Chaudhuri, Julian Michael, Shengjia Zhao, Summer Yue