arXiv Machine Learning

InfoDPP-PAC: Principled Patch Selection for Whole Slide Image Analysis

arXiv AI
Jun 2

CRISP -- Clustering-Based Redundancy-Reduced Instance Sampling for Pathology Case Representation and Retrieval

arXiv:2605. 24253v2 Announce Type: replace-cross Abstract: Digital pathology archives increasingly contain multiple whole-slide images (WSIs) per case, capturing spatially distinct tumour regions and reflecting intrinsic morphological heterogeneity.

By Zahra Rahimi Afzal, Wataru Uegami, Saghir Alfasly, Saba Yasir, Judy C. Boughey, Matthew P. Goetz, Krishna R. Kalari, H. R. Tizhoosh
arXiv Computer Vision
Aug 25

LanGuSTE: Language-Guided Coarse-to-Fine Patch Selection for Efficient Whole Slide Image Analysis

LanGuSTE is a patch‑selection framework for whole slide image analysis that uses vision‑language models and large language model knowledge. It introduces Cross‑Scale Visual Prompt Tuning to align low‑resolution and high‑resolution patches, and a coarse‑to‑fine selection module that encodes only informative high‑resolution patches. Experiments show LanGuSTE cuts overall processing time to about one‑third of the baseline while matching or surpassing diagnostic performance of exhaustive and state‑of‑the‑art methods.

By Yonghan Shin, Gangsu Kim, Won-Ki Jeong
arXiv Computer Vision
Sep 3

Synergistic Information Disentanglement for Omni-modal Slide Representation Learning in Computational Pathology

The paper introduces Φ-Omni, a self‑supervised learning framework for computational pathology that disentangles synergistic information across histology, genomics, and clinical reports using Partial Information Decomposition. By employing a Synergistic Information Bottleneck and a ΦID objective, the method suppresses redundant signals while maximizing irreducible cross‑modal synergy, leading to improved few‑shot performance on breast and lung whole‑slide image datasets. The authors demonstrate that Φ-Omni outperforms both supervised and other SSL baselines on eight external tasks.

By Mingxin Liu, Chengfei Cai, Anwen Lu, Pengbo Xu, Jun Li, Jinze Li, Depin Chen, Jun Xu
arXiv Computer Vision
Sep 7

MultiAttenGastro: Multi-Dimensional Attention Augmentation for Gastrointestinal Endoscopy Classification

MultiAttenGastro is a plug‑and‑play attention framework that adds parallel 1‑D channel, 2‑D spatial, and 3‑D contextual heads to existing CNN and transformer backbones for gastrointestinal endoscopy classification. Across eight backbones and five public GI datasets, the framework improves performance on large‑gap datasets such as Kvasir‑Capsule but shows no benefit on small‑gap benchmarks like Kvasir‑v2, with mixed results elsewhere. Analysis using Centered Kernel Alignment indicates that the gains are linked to representational redundancy: low inter‑head redundancy under large domain gaps yields consistent improvements, while high redundancy under small gaps leads to losses.

By Sadhana Devarajan, Praveen Kumar Chandaliya, Dhruvin Jashvant Kumar Shah, Kishor Upla, Kiran Raja
arXiv Machine Learning
Sep 3

Morphology signal in whole slide image foundation models can automatically triage slides

The paper introduces a pipeline that uses publicly available whole slide image foundation models (FMs) to automatically triage slides by ranking them based on zero‑shot classification predictions. This approach accurately identifies slides containing the most tumor, achieving top‑2 ranking for patients with up to 43 slides across multiple datasets. The study also proposes a ranked evaluation framework to benchmark FM performance in slide triage.

By Ayushi Sinha, Shashank Yadav, Benjamin Holmes, Pravat Das, Aaron W. Bogan, James S. Lewis Jr., Santiago Romero-Brufau, Andrew Y. K. Foong, Scott H. Kaufmann, Kathryn M. Van Abel, David M. Routman, Michael R. Lucas