arXiv AI By Duncan Stothers, Ren-Chin Wu, William Lotter

ADMIL: Attention-Distilled Multiple Instance Learning for Selective Foundation Model Inference in Pathology

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arXiv Computer Vision
Aug 25

LanGuSTE: Language-Guided Coarse-to-Fine Patch Selection for Efficient Whole Slide Image Analysis

LanGuSTE is a patch‑selection framework for whole slide image analysis that uses vision‑language models and large language model knowledge. It introduces Cross‑Scale Visual Prompt Tuning to align low‑resolution and high‑resolution patches, and a coarse‑to‑fine selection module that encodes only informative high‑resolution patches. Experiments show LanGuSTE cuts overall processing time to about one‑third of the baseline while matching or surpassing diagnostic performance of exhaustive and state‑of‑the‑art methods.

By Yonghan Shin, Gangsu Kim, Won-Ki Jeong
arXiv Computer Vision
Oct 12

Scaling Multi-Teacher Distillation for Digital Pathology

The paper introduces a scalable multi-teacher distillation (MTD) framework for digital pathology, addressing the poor performance of standard MTD when many teachers are used. By learning teacher‑specific representations through techniques such as learnable teacher tokens, a tailored attention scheme, mixture‑of‑experts layers, and a contrastive loss, the method scales effectively, enabling compact student encoders that are up to 10× more efficient than larger teacher models while matching or surpassing their performance on 39 tile‑ and slide‑level tasks. The authors release a new collection of efficient foundation models, OMNI, trained from ten state‑of‑the‑art teachers and provide an analysis of the complementary teacher‑specific representations.

By Sofi\`ene Boutaj, Pierre Marza, Varun Belagali, Dimitris Samaras, Maria Vakalopoulou, Stergios Christodoulidis
arXiv Computer Vision
Oct 16

Beyond Sparse Captions: Aligning Slide-Level Text and Patch-Level Vision in Pathology

The paper introduces Locked Image Multiple Instance PreTraining (LIMIT), a method that aligns slide‑level pathology reports with patch‑level visual features by freezing a vision encoder and fine‑tuning a text encoder. LIMIT uses report embeddings as cross‑attention queries over bags of patch features, optimizing slide representations via InfoNCE. Applying LIMIT, the authors create CONCH‑Z, which achieves state‑of‑the‑art zero‑shot performance on 22 pathology tasks, outperforming vision‑language encoders trained on curated caption datasets and narrowing the gap with larger slide‑level foundation models.

By Daniel Shao, Dongmin Bang, Luca L. Weishaupt, Sophia J. Wagner, Nic G. Reitsam, Ming Y. Lu, Long P. Le, Richard J. Chen, Faisal Mahmood