arXiv Computer Vision
Masked Feature Encoding for Large-Scale Whole Slide Image Representation
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arXiv Computer Vision
Sep 2
SlideMix: Enhancing Whole Slide Image Analysis via Multimodal Shuffling
arXiv:2609.00396v1 Announce Type: new Abstract: Histopathological whole slide images (WSIs) are central to cancer diagnosis, but their gigapixel scale, tissue heterogeneity, weak slide-level supervis...
arXiv AI
Sep 24
Do Center Biases Propagate? Robustness of Pathology Foundation Models in Whole-Slide Image Classification
The study investigates whether pathology foundation models (PFMs) carry center-related biases into whole-slide image (WSI) classification. By training models with increasing class-center correlations and evaluating six PFMs across four datasets and two MIL aggregators, the authors introduce the Area Under the Cramér's V Curve (AUCC) to measure both accuracy and degradation due to spurious correlations. Results reveal that center information propagates to WSI predictions, with robustness varying by PFM and MIL strategy, and that ComBat harmonization does not consistently improve robustness.
arXiv Computer Vision
Aug 25
LanGuSTE: Language-Guided Coarse-to-Fine Patch Selection for Efficient Whole Slide Image Analysis
LanGuSTE is a patch‑selection framework for whole slide image analysis that uses vision‑language models and large language model knowledge. It introduces Cross‑Scale Visual Prompt Tuning to align low‑resolution and high‑resolution patches, and a coarse‑to‑fine selection module that encodes only informative high‑resolution patches. Experiments show LanGuSTE cuts overall processing time to about one‑third of the baseline while matching or surpassing diagnostic performance of exhaustive and state‑of‑the‑art methods.
arXiv Machine Learning
Jun 8
LRMIL: Efficient Low-Resolution Multiple Instance Learning via High-Resolution Knowledge Distillation for Whole Slide Image Classification
arXiv:2606. 06864v1 Announce Type: cross Abstract: Multiple instance learning (MIL) has become a standard paradigm for whole slide image (WSI) analysis in digital pathology, as it enables slide-level prediction without dense annotations.
arXiv Computer Vision
Sep 30
HERO: Histology Encoder for Robust Representation in Oncology
HERO (Histology Encoder for Robust Representation in Oncology) is a ViT‑G/14 pathology foundation model trained with DINO and iBOT objectives and refined using high‑resolution Gram anchoring on a 500‑million‑tile corpus from about 575,000 clinical whole‑slide images. It demonstrates superior robustness to center, scanner, and stain variation compared to other state‑of‑the‑art foundation models, while maintaining competitive performance on tile‑level classification, segmentation, and gene‑expression prediction. Across 39 slide‑level clinical tasks, HERO ranks first on average and achieves the best average rank across six benchmark frameworks under an equal‑weighted analysis.
arXiv Computation and Language
Sep 22
SLICEChat: Progressive In-Encoder Token Pruning for Whole-Slide Pathology Language Models
arXiv:2609.24894v1 Announce Type: cross Abstract: Whole-slide pathology images (WSIs) contain gigapixel-scale visual content, creating a major scalability challenge for slide-level multimodal large l...