arXiv AI

Measuring Biological Capabilities and Risks of AI Agents

arXiv:2606. 19899v1 Announce Type: cross Abstract: This paper addresses a rapidly emerging policy challenge: how to generate and interpret credible evidence about the biological capabilities and risks of AI scientists, or agentic AI systems capable of autonomously or collaboratively performing multi-step scientific tasks.

arXiv AI
Aug 19

Traceable Trust for action-ready artificial intelligence in bioscience

The article introduces Traceable Trust, a framework designed to guide the transition from AI-generated outputs to laboratory actions in bioscience. It outlines a reviewable process that evaluates evidence, claimed capabilities, delegated agency, action thresholds, override mechanisms, and feedback loops. Three case studies demonstrate how the framework can document trust as AI outputs influence scientific work.

By Huayu Xin, Yizhi Cai, Mukilan Deivarajan Suresh, Gavin Michael Farrell, Iwona Gajda, Charlie Harrison, Conor Houghton, Mato Lagator, Yang Lu, Virginia Portillo, Reyer Zwiggelaar, Sebastian Lobentanzer
arXiv AI
Jul 22

BioSecBench-Refusal: A paired metric for performance and alignment in agentic biosecurity risk assessment

arXiv:2607. 05462v2 Announce Type: replace-cross Abstract: As AI agents are incorporated into life science workflows, the capabilities that speed discovery might also enable misuse.

By Edwin H. Wintermute, Harmon Bhasin, Christina M. Agapakis, Dianzhuo Wang, Evan Seeyave, Arjun Banerjee, Daniel Fulop, Matthew C. Watson, Adam J. Meyer, Sandrine Boissel, Jens H. Kuhn, Rishi Jain, Noah D. Taylor, Helena Shomar, Patrick M. Boyle, Kenny Workman
Hugging Face Trending Papers
Aug 18

Traceable Trust for action-ready artificial intelligence in bioscience

The paper introduces Traceable Trust, a framework designed to guide the transition from AI-generated outputs to laboratory actions in bioscience. It outlines a reviewable process that evaluates evidence, claimed capabilities, delegated agency, action thresholds, override authority, and feedback mechanisms. Three case studies demonstrate how the framework can document trust as AI outputs influence scientific work.

arXiv AI
Jul 8

Evaluating calibrated refusal and safe usefulness in dual-use biology settings

arXiv:2607. 05462v1 Announce Type: cross Abstract: As AI agents are incorporated into life science workflows, the capabilities that speed discovery might also enable misuse.

By Edwin H. Wintermute, Harmon Bhasin, Christina M. Agapakis, Dianzhuo Wang, Evan Seeyave, Arjun Banerjee, Daniel Fulop, Matthew C. Watson, Adam J. Meyer, Sandrine Boissel, Jens H. Kuhn, Rishi Jain, Noah D. Taylor, Helena Shomar, Patrick M. Boyle, Kenny Workman
arXiv AI
Sep 1

Science sandboxes measure the scientific capability of AI agents

arXiv:2608.30165v1 Announce Type: cross Abstract: Scientific progress depends not only on finding solutions, but on learning the rules that explain why they work and using that understanding to desig...

By Arya S. Rao, Rodrigo I. Castro, Sager J. Gosai, Kenneth B. Hsu, Yasha Ektefaie, Shantanu Singh, Sangeeta N. Bhatia, Steven K. Reilly, Ryan Tewhey, Eric S. Lander, Pardis C. Sabeti
Hugging Face Trending Papers
Jun 22

AI Scientists as Engines of Discovery: A Case for Development within Reformed Institutions

Agentic artificial intelligence (AI) systems are beginning to assist, accelerate, and partially automate scientific discovery, performing tasks that span literature synthesis, code generation, data analysis, hypothesis proposal, and model criticism. We argue that this transition is qualitative rather than incremental, and that suitably designed multi-agent systems may evolve from passive computational tools into ``AI scientists'' that can expand the hypothesis-generating and verification capacity of science.