arXiv AI

GRC-ProbNet: Uncertainty-aware Feature Extraction for Cardiovascular Disease Classification

arXiv:2607. 10357v1 Announce Type: cross Abstract: The automatic detection and classification of cardiovascular disease (CVD) from computed tomography (CT) images plays an important role in clinical practice.

arXiv Machine Learning
Jul 27

CARDIAG: A Dense Segment Classification Benchmark of Deep Learning Architectures for Coronary Angiography

arXiv:2607. 22139v1 Announce Type: cross Abstract: Accurate pixel-level classification of coronary angiograms is critical for cardiovascular disease assessment, yet the field lacks standardized evaluation protocols.

By Dominik Bernard Lau, Hubert Malinowski, Jerzy Szyjut, Adam Brzeski, Tomasz Dziubich, Rados{\l}aw Targo\'nski, Tomasz Figatowski, Natalia Zieli\'nska
arXiv AI
Sep 16

Beyond In-Distribution Metrics: A Systematic Out-of-Distribution Evaluation of Congenital Heart Disease Segmentation

The paper presents the first systematic evaluation of out‑of‑distribution generalization for congenital heart disease (CHD) segmentation, using the ImageCHD cohort as a held‑out target. It compares several segmentation architectures under different training regimes, showing that in‑distribution performance is a poor predictor of cross‑cohort robustness: nnU‑Net drops from 0.77 to 0.51 Dice, while SwinUNETR maintains higher performance at 0.67 Dice. Limited target‑domain adaptation with only 11 labeled ImageCHD cases boosts all SwinUNETR variants above 0.76 Dice, highlighting the importance of explicit cross‑dataset testing.

By Aniketh Vijesh, Shrisharanyan Vasu, Abhijit Ramesh, Clare Pomeroy-Ward, Harikrishnan Anil Maya, Sarin Xavier, Mahesh Kappanayil, Gilad Gressel
arXiv AI
Jul 14

A Unified Framework for Comprehensive Cardiac CT Segmentation and Phenotyping: Human-in-the-Loop Data Annotation, Vision Foundation Model Development, Multicenter Evaluation and Clinical Validation

arXiv:2607. 11287v1 Announce Type: cross Abstract: Comprehensive quantification of cardiac structures from computed tomography (CT) remains limited not by data availability but by the scalability of measurements, which makes routine use impractical.

By Pooya Mohammadi Kazaj, Leo Fridolin Weber, Wen Xie, Seyed Amir Ahmad Safavi-Naini, Anselm Stark, Giovanni Baj, Ali Mokhtari, Toshiya Yoshida, Christoph Ryffel, Taishi Okuno, Yoshihiro Akashi, Ronny R. Buechel, Thomas Pilgrim, Waldo Valenzuela, George C. M. Siontis, Xiaowei Xu, Moritz Hundertmark, Stephan Windecker, Christoph Grani, Isaac Shiri
arXiv Machine Learning
Aug 18

Beyond Boundary Noise: Aggregated Aleatoric Uncertainty Fails to Capture Presence Ambiguity in 3D Lung Nodule Segmentation

arXiv:2608. 14766v1 Announce Type: cross Abstract: Uncertainty estimation is critical for the safe clinical deployment of deep learning in medical image segmentation, with aleatoric uncertainty theoretically designed to capture irreducible data ambiguity.

By Simon Baur, Arne Schernich, Ekin B\"oke, Wojciech Samek, Jackie Ma
arXiv Computer Vision
Sep 21

Uncertainty-driven training for three-dimensional calibrated lung nodule classification

The paper introduces an uncertainty‑driven training framework for 3D CT lung nodule classification that uses validation‑based uncertainty estimates to reweight the loss, aiming to improve predictive performance and probability calibration. Two uncertainty quantification methods—Monte Carlo Dropout and Evidential Deep Learning—are evaluated across multiple backbone architectures (ResNet, DenseNet, EfficientNet, ViT, Swin) on the LIDC‑IDRI and NoduleMNIST3D datasets. The approach yields comparable classification accuracy to conventional training while substantially reducing expected calibration error, especially on convolutional backbones, and shows that simple temperature scaling can also achieve strong calibration.

By Giuseppe Tripodi, Alessandro De Rosis, Saleh Rezaeiravesh
arXiv Computer Vision
Aug 27

Improving Cross-Site Whole-Heart Segmentation

The paper presents a modality‑routed 3D cardiac segmentation pipeline that combines TotalSegmentator‑initialized nnU‑Netv2 models with site‑characterized, label‑preserving appearance augmentation. By analyzing measurable image properties across sites, the authors design a bias‑field plus Bezier augmentation strategy that smooths spatial intensity perturbations and remaps intensities nonlinearly, followed by class‑wise largest‑connected‑component cleanup. On held‑out validation splits, this approach raises CT mean Dice from 0.8350 to 0.9135 and MRI mean Dice from 0.7695 to 0.7830 while reducing HD95, demonstrating improved cross‑site robustness in limited‑data whole‑heart segmentation.

By Tanish Mudaliar, Justin Li, Daniel Lin, Julianna Vo, Kaitao Liao, Xin Wang, Shu Hu