UniReg is a conditional unified model for medical image registration that adapts deformation field estimation based on anatomical priors, registration type constraints, and instance-specific features. It combines the precision of task‑specific learning with the generalization of traditional optimization, enabling effective alignment across diverse CT and MR scenarios within a single framework. Experiments show UniReg outperforms state‑of‑the‑art learning‑based methods in accuracy while providing strong cross‑scenario generalization and reducing training cost and model redundancy.
By Zi Li, Jianpeng Zhang, Tai Ma, Tony C. W. Mok, Yan-Jie Zhou, Zeli Chen, Xianghua Ye, Le Lu, Cheng Chen, Dakai Jin
BINDER is a new probabilistic model for medical image registration that builds on mutual information and uses latent voxel‑wise correspondences to enable closed‑form iterative updates. The approach yields a demons‑like optimization algorithm that performs robustly on both monomodal and multimodal tasks, and a sampler that quantifies uncertainty in high‑dimensional 3D deformations. The authors provide the code on GitHub for public use.
By Stefano Cerri, Amirhossein Hassankhani, Ya\"el Balbastre, Koen Van Leemput
The paper introduces Recursive Uncertainty-Gated Image Registration (RUGI), an iterative refinement method that updates deformation fields predicted by learning-based registration models using a gating map. Two gating strategies are explored: an uncertainty-based approach and an image residual error approach, both concentrating updates on difficult regions. Experiments on cardiac MRI and echocardiography datasets show that RUGI consistently improves registration accuracy, with the error-gated variant reducing MSE by 27‑37% on pretrained models and lowering ejection fraction estimation errors.
By Clara Rodrigo Gonz\'alez, Oscar Bates, Fu Siong Ng, Meng-Xing Tang
arXiv:2606. 10713v1 Announce Type: cross Abstract: The nnU-Net has demonstrated continuous success in medical segmentation tasks, which heavily rely on the availability and diversity of annotated biomedical data.
By Ana Sofia Santos, Andr\'e Ferreira, Gijs Luijten, Naida Solak, Lisle Faray de Paiva, Behrus Hinrichs-Puladi, Jens Kleesiek, Jan Egger, Victor Alves
arXiv:2410.14083v2 Announce Type: replace
Abstract: This paper describes a new spatial correspondence representation based on paired regions-of-interest (ROIs), for medical image registration. The di...
By Shiqi Huang, Tingfa Xu, Ziyi Shen, Shaheer Ullah Saeed, Wen Yan, Dean Barratt, Yipeng Hu
arXiv:2607. 23343v1 Announce Type: cross Abstract: Intraoperative 2D/3D registration aligns preoperative CT volumes with intraoperative X-ray or fluoroscopic images and is essential for image-guided interventions.
By Minheng Chen, Youyong Kong
arXiv:2609.15669v1 Announce Type: cross
Abstract: Multimodal image registration is a key component of many clinical workflows, yet it remains challenging because corresponding anatomical structures o...
By Matteo Barbieri, Giammarco La Barbera, Juan Pablo De La Plata, Sabine Sarnacki, Isabelle Bloch, Pietro Gori
arXiv:2512. 17605v2 Announce Type: replace-cross Abstract: Robust mammography registration is essential for clinically relevant applications like tracking disease progression in breast tissue.
By Svetlana Krasnova, Emiliya Starikova, Ilia Naletov, Andrey Krylov, Dmitry Sorokin
Multimodal image registration is a key component of many clinical workflows, yet it remains challenging because corresponding anatomical structures often exhibit substantially different image intensit...
arXiv:2606. 27818v1 Announce Type: cross Abstract: We present MMD-Reg, a novel correspondence-free approach to point-cloud registration that is differentiable and has linear computational complexity in the number of points.
By Rixon Crane, Fahira Afzal Maken, Nicholas Lawrance, Stanislav Funiak, Kasra Khosoussi, Ming Xu, Russell Tsuchida
The paper investigates test‑time adaptation (TTA) techniques for 3D point‑cloud registration in laparoscopic surgery, where synthetic training data must be adapted to noisy, sparse, and occluded real intraoperative reconstructions. It adapts three families of TTA methods—model, normalization, and input adaptation—to handle asymmetric shifts between preoperative meshes and intraoperative clouds, replacing classification‑based entropy objectives with correspondence‑based ones. Experiments on synthetic and real targets show that input adaptation consistently reduces registration error with low inference latency, making it the most promising approach for surgical applications.
By Nina Bodelot, Soufiane Belharbi, Eric Granger
Pix2Rep-v2 is a self‑supervised learning framework that learns pixel‑ and voxel‑level representations for dense medical imaging tasks, using a redundancy‑reduction objective and equivariance principles to scale to 3D and wide field‑of‑view data. The method is evaluated on four datasets across multiple modalities, tasks, and backbones, demonstrating higher data‑efficiency in few‑shot scenarios and competitive performance, such as a +9.3 Dice point improvement in one‑shot segmentation on the M&Ms‑2 dataset. An in‑context dense prototype approach is also proposed, eliminating the need for downstream training.
By S. Sifaoui, E. Angelini, S. Toupin, T. Pezel, L. Le Folgoc