arXiv:2606. 03322v1 Announce Type: cross Abstract: The graphical representation of the brain offers critical insights into diagnosing and prognosing neurodegenerative disease via relationships between regions of interest (ROIs).
By Jaeyoon Sim, Minjae Lee, Guorong Wu, Won Hwa Kim
arXiv:2603. 19100v2 Announce Type: replace Abstract: Electroencephalography (EEG) enables non-invasive monitoring of brain activity across clinical and neurotechnology applications, yet building foundation models for EEG remains challenging due to differing electrode topologies and computational scalability, as Transformer architectures incur quadratic sequence complexity.
By Dana\'e Broustail, Anna Tegon, Thorir Mar Ingolfsson, Yawei Li, Luca Benini
The paper introduces Diffusion-Conditioned Representation Alignment (DCRA), a training framework that uses the forward diffusion process as a structured corruption scheduler for time‑series representation learning. DCRA aligns representations across noise levels with a feature‑level consistency objective, preserving class‑discriminative structure and enabling smooth, semantically coherent trajectories in latent space. Experiments on the CHB‑MIT EEG dataset demonstrate that DCRA improves seizure detection performance under various noise conditions, achieving higher sensitivity at low false‑positive rates and producing more balanced, structured representations than baseline methods.
By Wenrui Xu, Anas Enanaa, Keshab K. Parhi
arXiv:2602. 18195v2 Announce Type: replace-cross Abstract: Alzheimer's disease (AD) alters brain electrophysiology and disrupts multichannel EEG dynamics, making accurate and clinically useful EEG-based diagnosis increasingly important for screening and disease monitoring.
By Yicheng Feng, Hairong Chen, Ziyu Jia, Samir Bhatt, Hengguan Huang
arXiv:2510. 11917v2 Announce Type: replace Abstract: Dementia disorders such as Alzheimer's disease (AD) and frontotemporal dementia (FTD) exhibit overlapping electrophysiological signatures in EEG that challenge accurate diagnosis.
By Jun-En Ding, Anna Zilverstand, Shihao Yang, Albert Chih-Chieh Yang, Feng Liu
arXiv:2606. 00180v1 Announce Type: cross Abstract: Deep learning-based Major Depressive Disorder (MDD) detection using Electroencephalography (EEG) is fundamentally constrained by the "small-sample dilemma.
By Xiaojing Chen, Jingqi Cheng, Xu Zhao, Wan Jiang, Jingjing Wu
arXiv:2603. 20452v2 Announce Type: replace Abstract: Longitudinal neuroimaging is essential for modeling disease progression in Alzheimer's disease (AD), yet irregular sampling and missing visits pose substantial challenges for learning reliable temporal representations.
By Ruiying Chen, Yutong Wang, Houliang Zhou, Wei Liang, Yong Chen, Lifang He
arXiv:2604. 22700v2 Announce Type: replace Abstract: Modeling and predicting neurodegenerative disease progression from medical images remains a major challenge in medical AI, with significant implications for early diagnosis, disease monitoring, and treatment planning.
By Nivetha Jayakumar, Swakshar Deb, Bahram Jafrasteh, Qingyu Zhao, Miaomiao Zhang
arXiv:2603. 05693v2 Announce Type: replace-cross Abstract: Accurate longitudinal analysis of brain MRI is often hindered by evolving lesions, which bias automated neuroimaging pipelines.
By Zahra Karimaghaloo, Dumitru Fetco, Haz-Edine Assemlal, Hassan Rivaz, Douglas L. Arnold
arXiv:2609.24324v1 Announce Type: new
Abstract: Electroencephalography (EEG) provides a non-invasive window into dynamic brain activity, yet modeling long-horizon EEG sequences remains challenging du...
By Weishan Ye, Yue Pan, Li Zhang, Gan Huang, Zhen Liang
EEGDM introduces a self‑supervised framework that uses latent diffusion models to generate EEG signals, moving beyond traditional masked reconstruction. The method employs an EEG encoder to produce a compact representation that conditions the diffusion denoising process, allowing joint optimization of encoder and generator. Experiments demonstrate that EEGDM can reconstruct high‑quality EEG, learn robust representations, and perform competitively on various downstream tasks.
By Shaocong Wang, Tong Liu, Yihan Li, Ming Li, Kairui Wen, Pei Yang, Wenqi Ji, Minjing Yu, Yong-Jin Liu
The paper presents a diagnostic framework for Alzheimer’s disease that uses the Large Brain Model (LaBraM), a foundation model pretrained on over 2,500 hours of EEG data, to generate high‑dimensional latent embeddings. These embeddings are fed into a non‑linear Random Forest classifier, achieving an ROC‑AUC of 89.36% ± 3.49%, PR AUC of 81.45% ± 4.43%, and Balanced Accuracy of 82.44% ± 4.34% in a subject‑independent 5‑fold cross‑validation setting, using only 8‑second EEG segments. Post‑hoc occlusion and neurophysiological alignment analyses confirm that the model captures clinically validated biomarkers such as occipital‑frontal Alpha and Theta rhythm degradation and correlates with cognitive performance and clinical severity.
By Maggie Lin, Chung-Lin Hou, Tzyy-Ping Jung