arXiv Machine Learning

GraM-Diff: A Unified Graph-Mamba Diffusion Framework for EEG-Based Alzheimer's Disease Data Generation and Diagnosis

arXiv AI
Jun 8

LuMamba: Latent Unified Mamba for Electrode Topology-Invariant and Efficient EEG Modeling

arXiv:2603. 19100v2 Announce Type: replace Abstract: Electroencephalography (EEG) enables non-invasive monitoring of brain activity across clinical and neurotechnology applications, yet building foundation models for EEG remains challenging due to differing electrode topologies and computational scalability, as Transformer architectures incur quadratic sequence complexity.

By Dana\'e Broustail, Anna Tegon, Thorir Mar Ingolfsson, Yawei Li, Luca Benini
arXiv Machine Learning
Sep 14

DCRA: Diffusion-Conditioned Representation Alignment for Robust Time-Series Learning

The paper introduces Diffusion-Conditioned Representation Alignment (DCRA), a training framework that uses the forward diffusion process as a structured corruption scheduler for time‑series representation learning. DCRA aligns representations across noise levels with a feature‑level consistency objective, preserving class‑discriminative structure and enabling smooth, semantically coherent trajectories in latent space. Experiments on the CHB‑MIT EEG dataset demonstrate that DCRA improves seizure detection performance under various noise conditions, achieving higher sensitivity at low false‑positive rates and producing more balanced, structured representations than baseline methods.

By Wenrui Xu, Anas Enanaa, Keshab K. Parhi
arXiv AI
Sep 28

LEAD: An EEG Foundation Model for Alzheimer's Disease Detection

LEAD is a gated temporal‑spatial Transformer foundation model designed for EEG‑based Alzheimer's disease detection. It was trained on the world’s largest EEG‑AD corpus of 2,238 subjects and uses a subject‑regularized strategy and medical contrastive learning across 13 datasets. LEAD outperforms existing methods on five downstream AD datasets, achieving the best average ranking across 20 evaluations.

By Yihe Wang, Nan Huang, Nadia Mammone, Marco Cecchi, Xiang Zhang
arXiv Machine Learning
Jun 25

SDE-Driven Spatio-Temporal Hypergraph Neural Networks for Irregular Longitudinal fMRI Connectome Modeling in Alzheimer's Disease

arXiv:2603. 20452v2 Announce Type: replace Abstract: Longitudinal neuroimaging is essential for modeling disease progression in Alzheimer's disease (AD), yet irregular sampling and missing visits pose substantial challenges for learning reliable temporal representations.

By Ruiying Chen, Yutong Wang, Houliang Zhou, Wei Liang, Yong Chen, Lifang He
arXiv Computer Vision
Aug 21

4DLoG: Generative Modeling of Neurodegenerative Brain Anatomy with 4D Longitudinal Diffusion Model

arXiv:2604. 22700v2 Announce Type: replace Abstract: Modeling and predicting neurodegenerative disease progression from medical images remains a major challenge in medical AI, with significant implications for early diagnosis, disease monitoring, and treatment planning.

By Nivetha Jayakumar, Swakshar Deb, Bahram Jafrasteh, Qingyu Zhao, Miaomiao Zhang