arXiv:2606. 30398v1 Announce Type: new Abstract: Accurately predicting the temporal evolution of clinical biomarkers is crucial for the early diagnosis and management of neurodegenerative diseases such as Alzheimer's disease.
By Yujee Song, Seunghun Baek, Guorong Wu, Won Hwa Kim
arXiv:2608.29755v1 Announce Type: new
Abstract: Electroencephalography (EEG) is a promising, non-invasive, and cost-effective modality for Alzheimer's disease (AD) detection, but deep learning method...
By M. Tanveer, Ayush Singh Rana, Sanskriti Jain, Arnav Kumar, Aryaman Tiwari, A. Rahaman, A. Quadir, M. Sajid
The paper presents a diagnostic framework for Alzheimer’s disease that uses the Large Brain Model (LaBraM), a foundation model pretrained on over 2,500 hours of EEG data, to generate high‑dimensional latent embeddings. These embeddings are fed into a non‑linear Random Forest classifier, achieving an ROC‑AUC of 89.36% ± 3.49%, PR AUC of 81.45% ± 4.43%, and Balanced Accuracy of 82.44% ± 4.34% in a subject‑independent 5‑fold cross‑validation setting, using only 8‑second EEG segments. Post‑hoc occlusion and neurophysiological alignment analyses confirm that the model captures clinically validated biomarkers such as occipital‑frontal Alpha and Theta rhythm degradation and correlates with cognitive performance and clinical severity.
By Maggie Lin, Chung-Lin Hou, Tzyy-Ping Jung
arXiv:2603. 19100v2 Announce Type: replace Abstract: Electroencephalography (EEG) enables non-invasive monitoring of brain activity across clinical and neurotechnology applications, yet building foundation models for EEG remains challenging due to differing electrode topologies and computational scalability, as Transformer architectures incur quadratic sequence complexity.
By Dana\'e Broustail, Anna Tegon, Thorir Mar Ingolfsson, Yawei Li, Luca Benini
arXiv:2602. 00541v2 Announce Type: replace Abstract: Clinical events captured in Electronic Health Records (EHR) are irregularly sampled and may consist of a mixture of discrete events and numerical measurements, such as laboratory values or treatment dosages.
By Zilin Jing, Vincent Jeanselme, Yuta Kobayashi, Simon A. Lee, Chao Pang, Aparajita Kashyap, Yanwei Li, Xinzhuo Jiang, Shalmali Joshi
arXiv:2603. 20452v2 Announce Type: replace Abstract: Longitudinal neuroimaging is essential for modeling disease progression in Alzheimer's disease (AD), yet irregular sampling and missing visits pose substantial challenges for learning reliable temporal representations.
By Ruiying Chen, Yutong Wang, Houliang Zhou, Wei Liang, Yong Chen, Lifang He
Electroencephalography (EEG) provides a non-invasive window into dynamic brain activity, yet modeling long-horizon EEG sequences remains challenging due to their high temporal complexity, substantial...
The paper introduces a sparse Bayesian time‑varying regression framework that models pairwise EEG channel interactions and performs temporal feature selection for P300 brain‑computer interfaces. Using a relaxed‑thresholded Gaussian process prior, the method achieves a median character‑level accuracy of 96.4% on a public P300 speller dataset and outperforms both statistical and deep learning baselines. It also yields subgroup‑specific gains, notably for participants who abstain from alcohol, and improves median BCI‑Utility by over 10%, reaching peak throughput after only six sequence repetitions.
By Guoxuan Ma, Yuan Zhong, Moyan Li, Yuxiao Nie, Jian Kang
arXiv:2502.04892v2 Announce Type: replace-cross
Abstract: Learning robust representations from functional magnetic resonance imaging (fMRI) is fundamentally challenged by the temporal irregularity an...
By Joonhyeong Park, Byoungwoo Park, Chang-Bae Bang, Jungwon Choi, Hyungjin Chung, Byung-Hoon Kim, Juho Lee
arXiv:2606. 19888v1 Announce Type: cross Abstract: Modeling long-sequence medical time series data, such as electrocardiograms (ECG), poses significant challenges due to high sampling rates, multichannel signal complexity, inherent noise, and limited labeled data.
By Feng Wu, Harsh Deep, Eric Lehman, Sanyam Kapoor, Guoshuai Zhao, Rahul Krishnan, Gari Clifford, Li-wei H Lehman
arXiv:2608.21673v1 Announce Type: cross
Abstract: Longitudinal electronic health records (EHRs) document patients' sequences of clinical visits over time, preserving the temporal evolution of disease...
By Ximiao Li, Lin Jiang, Rongchao Xu, Dahai Yu, Zhe He, Guang Wang
arXiv:2607. 14314v1 Announce Type: new Abstract: Seizure diagnosis from EEG signals is a critical yet persistently challenging task, due to the complicated neural dynamics and the spurious connections in inter-channel modeling.
By Lincan Li, Zheng Chen, Yushun Dong