arXiv AI

CACSurv: Concordance-Aligned Comparative Learning with Large Language Models for Cancer Survival Prediction

arXiv:2608. 16594v1 Announce Type: new Abstract: Cancer survival prediction supports treatment planning, risk stratification, and follow-up management.

arXiv Computation and Language

3d ago

Large Language Models are Approximate Survival Estimators

arXiv:2609.38181v1 Announce Type: new Abstract: Survival analysis estimates time-to-event outcomes from patient covariates and is widely used for medical risk assessment. Patients seeking prognostic...

By Juan M Zambrano Chaves, Peniel Argaw, Risa Ueno, Carlo Bifulco, Kristina Young, Rom Leidner, Tristan Naumann, Hoifung Poon

llms benchmarks

arXiv AI

Jun 3

Aligning Data-Driven Predictors with Allocation: A Decision-Focused Approach to Survival Analysis

arXiv:2606. 02671v1 Announce Type: cross Abstract: Machine learning predictors have become essential tools for guiding automated decision making.

By Itai Zilberstein, Ioannis Anagnostides, Tuomas Sandholm

arXiv Machine Learning

Jun 2

OncoReason: Structuring Clinical Reasoning in LLMs for Robust and Interpretable Survival Prediction

arXiv:2510. 17532v2 Announce Type: replace-cross Abstract: Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data.

By Raghu Vamshi Hemadri, Geetha Krishna Guruju, Kristi Topollai, Anna Ewa Choromanska

llms nlp reinforcement-learning fine-tuning benchmarks safety

arXiv Machine Learning

Jul 21

Value-Monotonicity Matters: A Concordance Loss for Deep Survival Prediction

arXiv:2607. 16802v1 Announce Type: new Abstract: Deep survival models are evaluated almost exclusively by the concordance index (C-index), yet they are commonly trained using likelihood objectives such as the Cox partial likelihood, discrete-time negative log-likelihood, and DeepHit likelihood.

By Meixu Chen, Kai Wang, Jing Wang

arXiv AI

Jun 11

Tabular Foundation Models for Clinical Survival Analysis via Survival-Aware Adaptation

arXiv:2606. 12006v1 Announce Type: cross Abstract: Predicting time-to-event outcomes such as mortality is a fundamental task in clinical decision-making, commonly addressed through survival analysis.

By Minh-Khoi Pham, Luca Cotugno, Alina Sirbu, Tai Tan Mai, Martin Crane, Marija Bezbradica

fine-tuning benchmarks

arXiv Machine Learning

Aug 19

MultiSigBERT: Beyond Survival Analysis through Multimodal and Sequential Modeling in Oncology

MultiSigBERT is a unified framework that performs multimodal sequential survival modeling in oncology by integrating narrative clinical reports, numerical measurements, and structured variables. The method converts free-text reports into sentence embeddings, compresses them with modality-specific PCA, and concatenates them with structured covariates to create joint temporal trajectories. These trajectories are encoded using the Signature transform from Rough Paths theory, and the resulting high-dimensional features are fed into a LASSO-regularized Cox model, achieving a concordance index of 0.743 on an independent test set of over 2,500 patients.

By Paul Minchella, St\'ephane Chr\'etien, Guillaume Metzler, Lo\"ic Verlingue, R\'emi Vaucher

rag multimodal

arXiv AI

Jul 10

Towards Precision Therapy in Hepatocellular Carcinoma: A Clinical-Reasoning LLM for Risk Stratification and Treatment Guidance

arXiv:2607. 08602v1 Announce Type: new Abstract: Hepatocellular carcinoma (HCC) is a common malignancy and a leading cause of cancer-related mortality.

By Peng Cui, Jitao Wang, Siyan Xue, Yao Huang, Haoming Xia, Dong Li, Dengxiang Liu, Weilin Wang, Liping Liu, Leida Zhang, Yunfu Cui, Tao Peng, Daolin Ji, Haitao Zhao, Wei Zhang, Xiaojuan Wang, Weijie Ma, Zongren Ding, Jinlong Li, Yuan Ding, Jiajing Zhao, Zhiyu Chen, Chengkun Yang, Ziyue Huang, Jiaqi Liu, Fusheng Liu, Yang Zhou, Xiaojuan Wang, Zhongquan Sun, Shiyun Bao, Xiaojun Wang, Ming Yang, Guangxin Li, Bin Shu, Yong Liao, Hongxuan Li, Yao Tang, Shizhong Yang, Yongyi Zeng, Yufeng Yuan, Yinpeng Dong, Jihui Hao, Jun Zhu, Jiahong Dong

llms benchmarks

arXiv AI

Aug 5

SAGE: Semantic Explainability of Attention-Based Survival Models in Computational Pathology

arXiv:2608. 02803v1 Announce Type: cross Abstract: Attention-based multiple instance learning (ABMIL) is the predominant approach for slide-level prediction in computational pathology, yet its attention maps provide only local explanations: they indicate where a model focuses but not which histological features drive its predictions or how the model behaves across a patient cohort.

By Abdallah Lamane, Abdul Rahman Diab, Ren-Chin Wu, William Lotter

llms multimodal benchmarks

arXiv Machine Learning

Aug 26

A Multimodal Foundation Model for Longitudinal Patient Representation and Scalable Insight Generation in Oncology

arXiv:2608.24688v1 Announce Type: new Abstract: Precision oncology necessitates a longitudinal model of patient state that captures cancer evolution and treatment over time, integrating multimodal ob...

By Eugene Vorontsov, Yi Kan Wang, Alican Bozkurt, Adam Casson, Ludmila Tydlitatova, Michal Zelechowski, Ezra E. W. Cohen, Jyoti D. Patel, Max Banaszak, Caitlin McWilliams, Shane Colley, Kate Sasser, Ryan Fukushima, Eric Lefkofsky, Razik Yousfi, Siqi Liu

rag multimodal benchmarks

arXiv Computer Vision

Sep 1

Multimodal Feature Prototype Learning for Interpretable and Discriminative Cancer Survival Prediction

arXiv:2510.06113v2 Announce Type: replace Abstract: Survival analysis plays a vital role in making clinical decisions. However, the models currently in use are often difficult to interpret, which red...

By Shuo Jiang, Zhuwen Chen, Liaoman Xu, Yanming Zhu, Changmiao Wang, Jiong Zhang, Feiwei Qin, Yifei Chen, Zhu Zhu

multimodal safety

arXiv AI

Jul 10

SHIFT: Survival Prediction from Incomplete and Heterogeneous Genomic Data

arXiv:2607. 07725v1 Announce Type: cross Abstract: Genomic prediction models often fail to transfer across institutions because sequencing panels differ across sites, creating structural feature missingness at deployment.

By Muhammet Sami Yavuz, Ayhan Can Erdur, Sabri Mustafa Kahya, Benedikt Wiestler, Jana Lipkova

llms

arXiv Machine Learning

Jun 4

SurvPFN: Towards Foundation Models for Survival Predictions

arXiv:2606. 04564v1 Announce Type: new Abstract: Tabular foundation models (TFMs) have made rapid progress in standard classification and regression, but time-to-event survival prediction tasks have remained largely untouched.

By Samuel B\"ohm (Institute of Epidemiology and Prevention, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany), Lennart Purucker (Department of Computer Science, University of Freiburg, Freiburg, Germany, PriorLabs, Freiburg, Germany), Frank Hutter (Department of Computer Science, University of Freiburg, Freiburg, Germany, PriorLabs, Freiburg, Germany), Pascal Schlosser (Institute of Epidemiology and Prevention, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, US, CIBSS - Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany)

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