Integrating heterogeneous biomedical data, including clinical metadata, histopathology images, and molecular profiles, is crucial for comprehensive disease understanding. However, gene expression data acquisition remains constrained by high costs and privacy concerns, limiting its use in multimodal research and AI-driven applications.
arXiv:2607. 21343v1 Announce Type: cross Abstract: Integrating heterogeneous biomedical data, including clinical metadata, histopathology images, and molecular profiles, is crucial for comprehensive disease understanding.
SynerMedGen is a unified framework that aligns medical multimodal understanding with generation tasks through task alignment. It introduces three generation‑aligned understanding tasks and a two‑stage training strategy that transfers representations learned during understanding to medical image synthesis. The model achieves strong zero‑shot performance on 22 synthesis tasks and outperforms state‑of‑the‑art specialized and unified models when combined with generation training, supported by a new 1M‑sample SynerMed dataset.
LatentVerse is a new framework that provides a web-based visual analytics platform and a command-line interface for analyzing multimodal latent representations. It unifies diagnostics for representation quality metrics and extends analysis to multimodal settings by decomposing embeddings into shared and modality-specific components. The authors evaluate the tool through simulations, real biomedical data analyses, and a user study, demonstrating its utility for interpretable evaluation of foundation model representations.
The paper introduces StyleGANCA, a lightweight neural cellular automata (NCA) based generative adversarial network designed for medical image synthesis. By combining a StyleGAN-inspired mapping network with adaptive style modulation in a multi-scale NCA framework, the model achieves high-quality image generation with far fewer parameters than existing adversarial, variational, diffusion, and NCA baselines. Experiments on BloodMNIST and PathMNIST show competitive FID and KID scores, and the synthetic images preserve class-specific information, effectively supporting downstream multi-class classifier training.
The paper introduces SMILE, a self‑explainable multimodal information bottleneck framework for medical diagnosis. It jointly optimizes predictive accuracy and modality‑specific explainability by selecting the most informative elements within each data modality. Experiments on diverse medical datasets show strong diagnostic performance, including a 9.1‑percentage‑point accuracy gain on the iCTCF dataset, and provide transparent, modality‑aware explanations that enhance both explainability and generalization.
arXiv:2608. 13256v1 Announce Type: cross Abstract: As biomedical research increasingly relies on data-intensive tools, the quality and utility of datasets are critical.
arXiv:2608.28787v1 Announce Type: new Abstract: Joint-embedding predictive architectures (JEPAs) have primarily been developed for self-supervised representation learning. Denoising JEPA (D-JEPA) rec...
arXiv:2510.06113v2 Announce Type: replace Abstract: Survival analysis plays a vital role in making clinical decisions. However, the models currently in use are often difficult to interpret, which red...
arXiv:2607. 01656v1 Announce Type: new Abstract: The interaction between brain structure and genetic influences is key to understanding neuropsychiatric disorders.
arXiv:2606. 17115v1 Announce Type: cross Abstract: Foundation models (FMs) have emerged as powerful representation extractors for medical data, yet their generalizability to datasets under distribution shift remains underexplored.
arXiv:2512. 09185v4 Announce Type: replace-cross Abstract: Understanding disease progression is a central clinical challenge with direct implications for early diagnosis and personalized treatment.
arXiv:2606. 07640v1 Announce Type: cross Abstract: This study investigates the trade-offs between fidelity, privacy, and utility in synthetic data generation under conditions of data scarcity and privacy sensitivity.