The paper introduces MedUAG, a unified medical multimodal model that supports both understanding and generation tasks. It presents MedUAGCorpus, the largest dataset of over 6 million instances across 14 imaging modalities, and MedUAGBench, a benchmark covering 12 diverse generation tasks with standardized protocols. Experiments show that MedUAG performs strongly across many medical understanding and generation tasks, setting a competitive baseline for future medical multimodal systems.
By Zijie Meng, Yuncheng Zhang, Hualiang Wang, Yitian Tang, Xiaotang Gai, Chen Shen, Songtao Jiang, Shaosheng Cao, Jian Wu, Xian Wu, Zuozhu Liu
MedGEN-Bench is a new benchmark for open‑ended multimodal medical generation that addresses limitations in current medical visual benchmarks, such as query‑image misalignment, closed‑ended answer spaces, and text‑centric outputs. The dataset contains 6,422 image‑text pairs across six imaging modalities, 15 clinical tasks, and 27 subtasks, including VQA, image editing, and contextual multimodal generation pairs. Evaluation combines reference‑based fidelity metrics with a structured, checklist‑guided assessment by a medical VLM judge, and preliminary results show that image‑output tasks remain unsaturated while contextual augmentation improves image‑instruction similarity.
By Junjie Yang, Yuhao Yan, Gang Wu, Rui Qian, Zhisheng Chen, Haijiang Li, Yuhe Wu, Qichao Zhao, Dawen Tian, Xiang Wan, Fenglei Fan, Wenjian Qin, Yongquan Zhang, Feiwei Qin, Changmiao Wang
UReason is a benchmark that evaluates how well unified multimodal models (UMMs) align textual reasoning with image generation. It contains 2,000 human‑curated instances across five reasoning‑intensive tasks—Code, Arithmetic, Spatial, Attribute, and Text—and compares direct generation, reasoning‑guided generation, and decontextualized generation. The study finds that while reasoning‑guided generation improves over direct generation, decontextualized generation consistently outperforms it, indicating that the visual semantics in textual reasoning are not reliably reflected in the generated images.
By Cheng Yang, Chufan Shi, Bo Shui, Yaokang Wu, Muzi Tao, Huijuan Wang, Ivan Yee Lee, Yong Liu, Xuezhe Ma, Taylor Berg-Kirkpatrick
arXiv:2610.06896v1 Announce Type: new
Abstract: Frontier multimodal large language models (MLLMs) are increasingly positioned as general purpose visual reasoners as part of the quest for artificial g...
By Ross Callaghan, Niannu Gao, Hojjat Azadbakht, Hui Zhang
The paper investigates how visual understanding and generation objectives interact within unified multimodal models (UMMs). At the representation level, each objective enriches the other, but forcing them through the same computation path can cause one to dominate; a task‑decoupled architecture mitigates this. At the task and system levels, the authors demonstrate bidirectional transfer between shared knowledge and superior performance of an end‑to‑end UMM over a planner–executor pipeline on complex tasks.
By Penghao Wu, Haiwen Diao, Weichen Fan, Lewei Lu, Dahua Lin, Ziwei Liu
arXiv:2607. 24743v1 Announce Type: cross Abstract: Multimodal large language models (MLLMs) hold immense potential to revolutionize clinical practice, yet deploying them in the medical domain is fundamentally a vision-centric challenge: models must absorb knowledge from heterogeneous 2D and 3D medical images, and evaluation protocols must align with radiologists' clinical practice and provide an accurate, fine-grained and factualness-driven assessment.
By Hangjie Yuan, Yichen Qian, Zhiwei Tang, Xianzhe Xu, Lirong Wu, Sicheng Yang, Jinwang Wang, Pengju Wang, Zhitao Zeng, Yizeng Han, Yan Xing, Shengxuan Luo, Tao Feng, Qing Xie, Weigen Yao, Yi Yang, Zuozhu Liu, Jiasheng Tang, Shaocheng Wang, Jitao Wang, Jiahong Dong, Weihua Chen, Feng Xu, Fan Wang
arXiv:2606. 12169v1 Announce Type: cross Abstract: High-stakes clinical use of large vision-language models (LVLMs) requires reasoning that is grounded in visual evidence and clinical knowledge, not just correct final answers.
By Negin Baghbanzadeh, Pritam Sarkar, Michael Colacci, Abeer Badawi, Adibvafa Fallahpour, Arash Afkanpour, Leonid Sigal, Ali Etemad, Elham Dolatabadi
arXiv:2607.12896v3 Announce Type: replace
Abstract: Medical image segmentation foundation models are expected to generalize across diverse clinical scenarios, yet existing universal methods remain fr...
By Yunzhou Li, Jiesi Hu, Yanwu Yang, Hanyang Peng, Chenfei Ye, Jianfeng Cao, Yixuan Yuan, Ting Ma
Lingshu is a medical‑specialized multimodal large language model that addresses key limitations of existing medical MLLMs, such as narrow knowledge coverage, hallucinations, and weak reasoning. The authors curate a comprehensive dataset combining medical imaging, texts, and general‑domain data, then train Lingshu in multiple stages to embed medical expertise and improve task performance. They also introduce MedEvalKit, a unified evaluation framework, and demonstrate that Lingshu outperforms current open‑source multimodal models on multimodal QA, text‑based QA, and medical report generation.
By Weiwen Xu, Hou Pong Chan, Long Li, Mahani Aljunied, Ruifeng Yuan, Jianyu Wang, Chenghao Xiao, Guizhen Chen, Chaoqun Liu, Zhaodonghui Li, Yu Sun, Junao Shen, Chaojun Wang, Jie Tan, Deli Zhao, Tingyang Xu, Hao Zhang, Yu Rong
The paper introduces a post‑training approach that enables a single inference process to transition from text reasoning to image synthesis, eliminating the need for explicit modality switching. Using the 14B BAGEL model, the authors demonstrate that targeted post‑training data and reward‑weighted training improve multimodal image generation across four independent T2I benchmarks. The study highlights the benefits of joint text‑image generation and strategic data selection for enhancing T2I performance.
By Jiahui Chen, Philippe Hansen-Estruch, Xiaochuang Han, Yushi Hu, Emily Dinan, Amita Kamath, Michal Drozdzal, Reyhane Askari-Hemmat, Luke Zettlemoyer, Marjan Ghazvininejad
arXiv:2609.34798v2 Announce Type: replace
Abstract: Recent medical multimodal models have benefited from larger corpora, broader modality coverage, and stronger reasoning-oriented training, yet effec...
By Guanghao Zhu, Zeyu Liu, Zhitian Hou, Pengkai Wang, Zhijie Sang, Shuo Cai, Yang Yu, Yuanyi Wang, Yanggan Gu, Congkai Xie, Jianmin Wu, Hongxia Yang
Multimodal large language models (MLLMs) hold immense potential to revolutionize clinical practice, yet deploying them in the medical domain is fundamentally a vision-centric challenge: models must absorb knowledge from heterogeneous 2D and 3D medical images, and evaluation protocols must align with radiologists' clinical practice and provide an accurate, fine-grained and factualness-driven assessment. In this paper, we introduce ClinFusion, a vision-centric MLLM designed for holistic medical understanding that systematically addresses these limitations.